UniProtKB - A0A0X3P7L8 (A0A0X3P7L8_SCHSO)
Protein
Protein pelota homolog
Gene
TR87229
Organism
Schistocephalus solidus (Tapeworm)
Status
Functioni
May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and degrade damaged mRNAs.UniRule annotation
Cofactori
a divalent metal cationUniRule annotationARBA annotation
GO - Molecular functioni
- endonuclease activity Source: UniProtKB-KW
- metal ion binding Source: UniProtKB-KW
GO - Biological processi
- nuclear-transcribed mRNA catabolic process, no-go decay Source: InterPro
- nuclear-transcribed mRNA catabolic process, non-stop decay Source: InterPro
- RNA surveillance Source: InterPro
Keywordsi
Molecular function | EndonucleaseUniRule annotationARBA annotation, Hydrolase, Nuclease |
Ligand | Metal-bindingUniRule annotationARBA annotation |
Names & Taxonomyi
Protein namesi | |
Gene namesi | ORF Names:TR87229Imported |
Organismi | Schistocephalus solidus (Tapeworm)Imported |
Taxonomic identifieri | 70667 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Spiralia › Lophotrochozoa › Platyhelminthes › Cestoda › Eucestoda › Diphyllobothriidea › Diphyllobothriidae › Schistocephalus |
Subcellular locationi
Keywords - Cellular componenti
CytoplasmUniRule annotationARBA annotation, NucleusUniRule annotationFamily & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 1 – 130 | eRF1_1InterPro annotationAdd BLAST | 130 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 371 – 410 | DisorderedSequence analysisAdd BLAST | 40 |
Sequence similaritiesi
Belongs to the eukaryotic release factor 1 family. Pelota subfamily.UniRule annotationARBA annotation
Family and domain databases
Gene3Di | 2.30.30.870, 1 hit 3.30.1330.30, 1 hit 3.30.420.60, 1 hit |
InterProi | View protein in InterPro IPR042226, eFR1_2_sf IPR005140, eRF1_1_Pelota IPR005141, eRF1_2 IPR005142, eRF1_3 IPR029064, L30e-like IPR038069, Pelota/DOM34_N IPR004405, Transl-rel_pelota |
PANTHERi | PTHR10853, PTHR10853, 1 hit |
Pfami | View protein in Pfam PF03463, eRF1_1, 1 hit PF03464, eRF1_2, 1 hit PF03465, eRF1_3, 1 hit |
SMARTi | View protein in SMART SM01194, eRF1_1, 1 hit |
SUPFAMi | SSF159065, SSF159065, 1 hit SSF55315, SSF55315, 1 hit |
TIGRFAMsi | TIGR00111, pelota, 1 hit |
i Sequence
Sequence statusi: Complete.
A0A0X3P7L8-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKLLSKNIDR YASGSITLVA ENEEDMWLTY NLVQVGDSFR CSTVRKVQTE
60 70 80 90 100
SATGSVASKQ IRMNLTVAVE TIDFDTQGSA LHLKGRNMEE NQYVKMGAYH
110 120 130 140 150
TLTIGVKDKF TIAKQEWDSV SLMLVEQAAD PTQQADVATV VMHEGLAYVC
160 170 180 190 200
LLTSSTMHVR AKIECTIPRK RPNLPTTQHD KGIARFFDQI IQAIERHVRF
210 220 230 240 250
DVVKCVIVAS PGFLREQFFE YLFQMATKEE KRVFLDNKSK FMLIHSSSGH
260 270 280 290 300
KHALKEVLSD PLVLSKISNT KAAAEITALN DFYQMLKVDS SRAFYGVKHV
310 320 330 340 350
EAAVEAFAVE TLLISDALFR SKDLTARKRF VGLVDSVKEN QGTVRIFSSL
360 370 380 390 400
HVSGEQLNQL SGIAAILRFP IPEPDSDEED SDDEEDQQEG QGTQLKPDVA
410
GPSLSAAATT
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | GEEE01015281 Transcribed RNA Translation: JAP47944.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | GEEE01015281 Transcribed RNA Translation: JAP47944.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Family and domain databases
Gene3Di | 2.30.30.870, 1 hit 3.30.1330.30, 1 hit 3.30.420.60, 1 hit |
InterProi | View protein in InterPro IPR042226, eFR1_2_sf IPR005140, eRF1_1_Pelota IPR005141, eRF1_2 IPR005142, eRF1_3 IPR029064, L30e-like IPR038069, Pelota/DOM34_N IPR004405, Transl-rel_pelota |
PANTHERi | PTHR10853, PTHR10853, 1 hit |
Pfami | View protein in Pfam PF03463, eRF1_1, 1 hit PF03464, eRF1_2, 1 hit PF03465, eRF1_3, 1 hit |
SMARTi | View protein in SMART SM01194, eRF1_1, 1 hit |
SUPFAMi | SSF159065, SSF159065, 1 hit SSF55315, SSF55315, 1 hit |
TIGRFAMsi | TIGR00111, pelota, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | A0A0X3P7L8_SCHSO | |
Accessioni | A0A0X3P7L8Primary (citable) accession number: A0A0X3P7L8 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 13, 2016 |
Last sequence update: | April 13, 2016 | |
Last modified: | August 12, 2020 | |
This is version 10 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |