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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Vibrio cholerae (strain MO10)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotationSAAS annotation

Pathwayi: gluconeogenesis

This protein is involved in the pathway gluconeogenesis, which is part of Carbohydrate biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway gluconeogenesis and in Carbohydrate biosynthesis.

Pathwayi: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose.UniRule annotationSAAS annotation
Proteins known to be involved in the 4 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Glucose-6-phosphate isomerase (pgi)
  3. ATP-dependent 6-phosphofructokinase (pfkA)
  4. no protein annotated in this organism
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei387UniRule annotation1
Active sitei515UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomeraseUniRule annotationSAAS annotationImported
Biological processGluconeogenesisUniRule annotationSAAS annotation, GlycolysisUniRule annotationSAAS annotation

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181
UPA00138

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
ORF Names:VchoM_03831Imported
OrganismiVibrio cholerae (strain MO10)Imported
Taxonomic identifieri345072 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
Proteomesi
  • UP000004687 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliA0A0X1L5M9
SMRiA0A0X1L5M9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotationSAAS annotation

Family and domain databases

CDDicd05015 SIS_PGI_1, 1 hit
cd05016 SIS_PGI_2, 1 hit
Gene3Di1.10.1390.10, 1 hit
HAMAPiMF_00473 G6P_isomerase, 1 hit
InterProiView protein in InterPro
IPR001672 G6P_Isomerase
IPR023096 G6P_Isomerase_C
IPR018189 Phosphoglucose_isomerase_CS
IPR035476 SIS_PGI_1
IPR035482 SIS_PGI_2
PANTHERiPTHR11469 PTHR11469, 1 hit
PfamiView protein in Pfam
PF00342 PGI, 1 hit
PRINTSiPR00662 G6PISOMERASE
PROSITEiView protein in PROSITE
PS00765 P_GLUCOSE_ISOMERASE_1, 1 hit
PS00174 P_GLUCOSE_ISOMERASE_2, 1 hit
PS51463 P_GLUCOSE_ISOMERASE_3, 1 hit

Sequencei

Sequence statusi: Complete.

A0A0X1L5M9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLKNINPTQT QAWKALTAHF ESAQDMDLKA LFAQDSERFA KYSARFGQDI
60 70 80 90 100
LVDYSKNLVN AETMQHLFAL AKETDLQSAI TAMFKGEAIN QTEDRAVLHT
110 120 130 140 150
ALRNRSNSPV LVNGEDVMPA VNAVLAKMKA FSERVIGGEW KGFTGKAITD
160 170 180 190 200
VVNIGIGGSD LGPYMVTEAL VPYKNHLTMH FVSNVDGTHM AETLKNVDPE
210 220 230 240 250
TTLFLVASKT FTTQETMTNA HTARDWFLKA AGDEAHVAKH FAALSTNGKA
260 270 280 290 300
VAEFGIDTDN MFEFWDWVGG RYSLWSAIGL SIILSIGYDN FVELLAGAHE
310 320 330 340 350
MDQHFVNTPF ESNIPVILAL IGIWYNNFHG AESEAILPYD QYLHRFAAYF
360 370 380 390 400
QQGNMESNGK YVDRNGNPVT YQTGPIIWGE PGTNGQHAFY QLIHQGTKLI
410 420 430 440 450
PCDFIAPAVS HNLVGDHHQK LMSNFFAQTE ALAFGKSAQA VQAELEKAGK
460 470 480 490 500
SAAEIAALVP FKVFEGNRPT NSILVKQITP RTLGNLIAMY EHKIFVQGVI
510 520 530 540 550
WNIFSFDQWG VELGKQLANQ ILPELADSAA VTSHDSSTNG LINAFKAFRA
Length:550
Mass (Da):60,691
Last modified:March 16, 2016 - v1
Checksum:i5E38B0421C3A1B16
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS990143 Genomic DNA Translation: EET25804.1
RefSeqiWP_000916643.1, NZ_DS990143.1

Genome annotation databases

EnsemblBacteriaiEET25804; EET25804; VchoM_03831

Similar proteinsi

Entry informationi

Entry nameiA0A0X1L5M9_VIBCO
AccessioniPrimary (citable) accession number: A0A0X1L5M9
Entry historyiIntegrated into UniProtKB/TrEMBL: March 16, 2016
Last sequence update: March 16, 2016
Last modified: March 28, 2018
This is version 14 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

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