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Protein

V-type proton ATPase subunit a

Gene

unc-32

Organism
Trichinella zimbabwensis
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.UniRule annotation

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processHydrogen ion transportUniRule annotation, Ion transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
V-type proton ATPase subunit aUniRule annotation
Gene namesi
Name:unc-32Imported
ORF Names:T11_8903Imported
OrganismiTrichinella zimbabwensisImported
Taxonomic identifieri268475 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaEnopleaDorylaimiaTrichinellidaTrichinellidaeTrichinella
Proteomesi
  • UP000055024 Componenti: Unassembled WGS sequence

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei438 – 462HelicalUniRule annotationAdd BLAST25
Transmembranei483 – 501HelicalUniRule annotationAdd BLAST19
Transmembranei571 – 591HelicalUniRule annotationAdd BLAST21
Transmembranei603 – 624HelicalUniRule annotationAdd BLAST22
Transmembranei687 – 706HelicalUniRule annotationAdd BLAST20
Transmembranei816 – 840HelicalUniRule annotationAdd BLAST25

Keywords - Cellular componenti

Membrane

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili51 – 71Sequence analysisAdd BLAST21
Coiled coili112 – 139Sequence analysisAdd BLAST28

Sequence similaritiesi

Belongs to the V-ATPase 116 kDa subunit family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixUniRule annotation

Family and domain databases

InterProiView protein in InterPro
IPR002490 V-ATPase_116kDa_su
IPR026028 V-type_ATPase_116kDa_su_euka
PANTHERiPTHR11629 PTHR11629, 1 hit
PfamiView protein in Pfam
PF01496 V_ATPase_I, 1 hit
PIRSFiPIRSF001293 ATP6V0A1, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All

A0A0V1I6J7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGSLFRSEEM CRCQLFLQTE ASYACVSELG ELGLVQFRDL NPDVTAFQRK
60 70 80 90 100
FVNEIRRCDE MERKLRFLEK EIKKDRIPIL DTSENPDAPL AREMIDLEVL
110 120 130 140 150
LTVRLFRMFS DLLVLKATFE KLDNELREVN MNEEMLKKNF LELTELKHIL
160 170 180 190 200
RKTQAFFDEQ ENIQAMQSLH ANDGNLGQVN PALEYDGELI VTGDHKESFG
210 220 230 240 250
GKLNLDFVVG VILRERIPAF ERLLWRACRG NVFLKQAEIT ESLEDPATGD
260 270 280 290 300
LVQKSVILIF FQGEQLKSRV KKICEGFRAT LYPCPETPQE RREMAIGVMT
310 320 330 340 350
RIEDLKTVLG QTQDHRHRVL VAAAKNIRIW FTKVRKIKSI YHTLNLFNLD
360 370 380 390 400
VTQKCLIAEC WCPVADLDKI QLALKRGTEE SGSSVPSILN RMYTTEAPPT
410 420 430 440 450
YNRTNKFTAG FQNIVDAYGV ASYREVNPAL YTIITFPFLF AIMFGDFGHG
460 470 480 490 500
LIMFLFALFL IVKEKQLIAR KIRDEVFNIF FGGRYIIFLM GLFSIYTGIV
510 520 530 540 550
YNEVYAKSVN IFGSSWMIPA EVDDNVLANV EKIQLNPNTS FLGHAYAYGL
560 570 580 590 600
DPAWNIAVNK LNFLNSFKMK MSVIIGVFQM LFGVVLSLFN YRFFNRKIDI
610 620 630 640 650
YTMFIPQMLF MCCIFLYLCI LIIYKWTVFS AAPADMAVGH YPGSHCAPSL
660 670 680 690 700
LIGLIFMFMF QQRNYGFGDS KCVTNAFYPG QVGFEQFLVV VAVLCAPTML
710 720 730 740 750
FVKPYLIYRE RKNRLKDGHI AIHADMNSDD TEAVQIKEKP SSSSSSSSAG
760 770 780 790 800
AHDEHDDMNI SEIFIIQAIH TIEFCLGCIS HTASYLRLWA LSLAHAQLSD
810 820 830 840 850
VLWAMVLRIA FGFQGYAGAI AVYLIVWAFG MLTICILVLM EGLSAFLHAL
860 870 880
RLHWVEFQSK FYTGSGYLFT PFSFDVILEQ ARIEDGD
Length:887
Mass (Da):101,362
Last modified:March 16, 2016 - v1
Checksum:iB0F8E245FDD96B99
GO

Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0V1I6B8A0A0V1I6B8_9BILA
V-type proton ATPase subunit a
unc-32 T11_8903
744Annotation score:
A0A0V1I7Z0A0A0V1I7Z0_9BILA
V-type proton ATPase subunit a
unc-32 T11_8903
695Annotation score:
A0A0V1I599A0A0V1I599_9BILA
V-type proton ATPase subunit a
unc-32 T11_8903
869Annotation score:
A0A0V1I6L6A0A0V1I6L6_9BILA
V-type proton ATPase subunit a
unc-32 T11_8903
654Annotation score:
A0A0V1I5A6A0A0V1I5A6_9BILA
V-type proton ATPase subunit a
unc-32 T11_8903
171Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JYDP01000004 Genomic DNA Translation: KRZ18036.1

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JYDP01000004 Genomic DNA Translation: KRZ18036.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

InterProiView protein in InterPro
IPR002490 V-ATPase_116kDa_su
IPR026028 V-type_ATPase_116kDa_su_euka
PANTHERiPTHR11629 PTHR11629, 1 hit
PfamiView protein in Pfam
PF01496 V_ATPase_I, 1 hit
PIRSFiPIRSF001293 ATP6V0A1, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A0V1I6J7_9BILA
AccessioniPrimary (citable) accession number: A0A0V1I6J7
Entry historyiIntegrated into UniProtKB/TrEMBL: March 16, 2016
Last sequence update: March 16, 2016
Last modified: April 25, 2018
This is version 7 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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