Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Negative regulator of P-body association

Gene

NBDY

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Promotes dispersal of P-body components and is likely to play a role in the mRNA decapping process.1 Publication

Caution

Was previously thought to be non-coding but has been shown to be translated and functional.1 Publication

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei30Required for interaction with EDC41 Publication1
Sitei34Required for interaction with EDC41 Publication1

GO - Biological processi

Keywordsi

Biological processmRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
Negative regulator of P-body associationImported
Alternative name(s):
P-body dissociating protein1 Publication
Protein NoBody1 Publication
Gene namesi
Name:NBDYImported
Synonyms:LINC01420Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome X

Organism-specific databases

HGNCiHGNC:50713 NBDY
MIMi300992 gene
neXtProtiNX_A0A0U1RRE5

Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Mutagenesisi22K → A: No effect on interaction with EDC4. 1 Publication1
Mutagenesisi23P → A: No effect on interaction with EDC4. 1 Publication1
Mutagenesisi24P → A: No effect on interaction with EDC4. 1 Publication1
Mutagenesisi25K → A: No effect on interaction with EDC4. 1 Publication1
Mutagenesisi26K → A: No effect on interaction with EDC4. 1 Publication1
Mutagenesisi27R → A: No effect on interaction with EDC4. 1 Publication1
Mutagenesisi28C → A: No effect on interaction with EDC4. 1 Publication1
Mutagenesisi29L → A: No effect on interaction with EDC4. 1 Publication1
Mutagenesisi30L → A: Impaired interaction with EDC4. 1 Publication1
Mutagenesisi32P → A: No effect on interaction with EDC4. 1 Publication1
Mutagenesisi33R → A: No effect on interaction with EDC4. 1 Publication1
Mutagenesisi34W → A: Impaired interaction with EDC4. 1 Publication1
Mutagenesisi35D → A: No effect on interaction with EDC4. 1 Publication1
Mutagenesisi36Y → A: No effect on interaction with EDC4. 1 Publication1
Mutagenesisi37P → A: No effect on interaction with EDC4. 1 Publication1
Mutagenesisi38E → A: No effect on interaction with EDC4. 1 Publication1
Mutagenesisi39G → A: No effect on interaction with EDC4. 1 Publication1
Mutagenesisi40T → A: No effect on interaction with EDC4. 1 Publication1
Mutagenesisi41P → A: No effect on interaction with EDC4. 1 Publication1

Organism-specific databases

OpenTargetsiENSG00000204272

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004392051 – 68Negative regulator of P-body associationAdd BLAST68

Proteomic databases

EPDiA0A0U1RRE5
MaxQBiA0A0U1RRE5

Expressioni

Gene expression databases

ExpressionAtlasiA0A0U1RRE5 baseline and differential

Interactioni

Subunit structurei

Interacts with mRNA decapping proteins DCP1A, DCP2 and EDC4.1 Publication

Structurei

3D structure databases

ProteinModelPortaliA0A0U1RRE5
SMRiA0A0U1RRE5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00390000004891
OMAiGDQPCTS

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

A0A0U1RRE5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGDQPCASGR STLPPGNARE AKPPKKRCLL APRWDYPEGT PNGGSTTLPS
60
APPPASAGLK SHPPPPEK
Length:68
Mass (Da):7,025
Last modified:February 17, 2016 - v1
Checksum:iFA372C7380B65853
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0U1RR68A0A0U1RR68_HUMAN
Negative regulator of P-body associ...
NBDY
40Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL158200 Genomic DNA No translation available.
AL354865 Genomic DNA No translation available.
KF459114 Genomic DNA No translation available.
CH471154 Genomic DNA Translation: EAW93234.1
CCDSiCCDS87751.1
RefSeqiNP_001335058.1, NM_001348129.1
UniGeneiHs.355559

Genome annotation databases

EnsembliENST00000374922; ENSP00000489583; ENSG00000204272
ENST00000423617; ENSP00000489486; ENSG00000204272
ENST00000637096; ENSP00000490217; ENSG00000204272
GeneIDi550643
KEGGihsa:550643

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL158200 Genomic DNA No translation available.
AL354865 Genomic DNA No translation available.
KF459114 Genomic DNA No translation available.
CH471154 Genomic DNA Translation: EAW93234.1
CCDSiCCDS87751.1
RefSeqiNP_001335058.1, NM_001348129.1
UniGeneiHs.355559

3D structure databases

ProteinModelPortaliA0A0U1RRE5
SMRiA0A0U1RRE5
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

EPDiA0A0U1RRE5
MaxQBiA0A0U1RRE5

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000374922; ENSP00000489583; ENSG00000204272
ENST00000423617; ENSP00000489486; ENSG00000204272
ENST00000637096; ENSP00000490217; ENSG00000204272
GeneIDi550643
KEGGihsa:550643

Organism-specific databases

CTDi550643
GeneCardsiNBDY
HGNCiHGNC:50713 NBDY
MIMi300992 gene
neXtProtiNX_A0A0U1RRE5
OpenTargetsiENSG00000204272
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00390000004891
OMAiGDQPCTS

Miscellaneous databases

ChiTaRSiLINC01420 human
PROiPR:A0A0U1RRE5
SOURCEiSearch...

Gene expression databases

ExpressionAtlasiA0A0U1RRE5 baseline and differential

Family and domain databases

ProtoNetiSearch...

Entry informationi

Entry nameiNBDY_HUMAN
AccessioniPrimary (citable) accession number: A0A0U1RRE5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 15, 2017
Last sequence update: February 17, 2016
Last modified: September 12, 2018
This is version 16 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  2. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again