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Protein
Submitted name:

C-myc promoter-binding protein

Gene

DENND4A

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
C-myc promoter-binding proteinImported
Gene namesi
Name:DENND4AImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 15

Organism-specific databases

HGNCiHGNC:24321 DENND4A

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000174485

PTM / Processingi

Proteomic databases

EPDiA0A0U1RR27
PeptideAtlasiA0A0U1RR27

Expressioni

Gene expression databases

ExpressionAtlasiA0A0U1RR27 baseline and differential

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini42 – 200MABPInterPro annotationAdd BLAST159
Domaini192 – 641UDENNInterPro annotationAdd BLAST450
Repeati809 – 843PPRPROSITE-ProRule annotationAdd BLAST35

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili513 – 533Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

GeneTreeiENSGT00760000118819
OMAiFLCFMAS

Family and domain databases

Gene3Di1.25.40.10, 1 hit
InterProiView protein in InterPro
IPR001194 cDENN_dom
IPR005112 dDENN_dom
IPR023341 MABP
IPR002885 Pentatricopeptide_repeat
IPR011990 TPR-like_helical_dom_sf
IPR037516 Tripartite_DENN
IPR005113 uDENN_dom
PfamiView protein in Pfam
PF03455 dDENN, 1 hit
PF02141 DENN, 1 hit
PF03456 uDENN, 1 hit
SMARTiView protein in SMART
SM00801 dDENN, 1 hit
SM00799 DENN, 1 hit
SM00800 uDENN, 1 hit
TIGRFAMsiTIGR00756 PPR, 1 hit
PROSITEiView protein in PROSITE
PS50211 DENN, 1 hit
PS51498 MABP, 1 hit
PS51375 PPR, 1 hit

Sequencei

Sequence statusi: Complete.

A0A0U1RR27-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIEDKGPRVA DYFVVAGLTD VSKPLEEEIH FNDACHKVAK PKEPITDVSV
60 70 80 90 100
IIKSLGEEVP QDYICIDVTP TGLSADLNNG SLVGPQIYLC YRRGRDKPPL
110 120 130 140 150
TDLGVLYDWK ERLKQGCEII QSTPYGRPAN ISGSTSSQRI YITYRRASEN
160 170 180 190 200
MTQNTLAVTD ICIIIPSKGE SPPHTFCKVD KNLNNSMWGS AVYLCYKKSV
210 220 230 240 250
AKTNTVSYKA GLICRYPQED YESFSLPESV PLFCLPMGAT IECWPSNSKY
260 270 280 290 300
PLPVFSTFVL TGASAEKVYG AAIQFYEPYS EENLTEKQRL LLGLTSADGK
310 320 330 340 350
SDSSKTIHTN KCICLLSHWP FFDAFRKFLT FLYRYSISGP HVLPIEKHIS
360 370 380 390 400
HFMHKVPFPS PQRPRILVQL SPHDNLILSQ PVSSPLPLSG GKFSTLLQNL
410 420 430 440 450
GPENAVTLLV FAVTEHKILI HSLRPSVLTS VTEALVSMIF PFHWPCPYVP
460 470 480 490 500
LCPLALADVL SAPCPFIVGI DSRYFDLYDP PPDVSCVDVD TNTISQIGDK
510 520 530 540 550
KNVAWKILPK KPCKNLMNTL NNLHQQLAKL QQRPRDDGLM DLAINDYDFN
560 570 580 590 600
SGKRLHMIDL EIQEAFLFFM ASILKGYRSY LRPITQAPSE TATDAASLFA
610 620 630 640 650
LQAFLRSRDR SHQKFYNMMT KTQMFIRFIE ECSFVSDKDA SLAFFDDCVD
660 670 680 690 700
KVDMDKSGEV RLIELDESFK SEHTVFVTPP EIPHLPNGEE PPLQYSYNGF
710 720 730 740 750
PVLRNNLFER PEGFLQAKKN KLPSKSSSPN SPLPMFRRTK QEIKSAHKIA
760 770 780 790 800
KRYSSIPQMW SRCLLRHCYG LWFICLPAYV KVCHSKVRAL KTAYDVLKKM
810 820 830 840 850
QSKKMDPPDE VCYRILMQLC GQYDQPVLAV RVLFEMQKAG IDPNAITYGY
860 870 880 890 900
YNKAVLESTW PSRSRSGYFL WTKVRNVVLG VTQFKRALKK HAHLSQTTLS
910 920 930 940 950
ADGSDLDAVS HGSMDSGHGT HTVEQAPFNT GLIKVYATDD RSSTGGQSDL
960 970 980 990 1000
GYNSLSKDEV RRGDTSTEDI QEEKDKKGSD CSSLSESEST KGSADCLPKL
1010 1020 1030 1040 1050
SYQNSSSIVR LTGTSNNSAG KISGESMEST PELLLISSLE DTNETRNIQS
1060 1070 1080 1090 1100
RCFRKRHKSD NETNLQQQVV WGNRNRNLSG GVLMGFMLNR INQEATPGDI
1110 1120 1130 1140 1150
VEKLGADAKI LSNVISKSTR PNTLDIGKPP LRSKRDSLEK ESSDDDTPFD
1160 1170 1180 1190 1200
GSNYLADKVD SPVIFDLEDL DSETDVSKAG CVATQNPKRI QRMNSSFSVK
1210 1220 1230 1240 1250
PFEKTDVATG FDPLSLLVAE TEQQQKEEEE EDEDDSKSIS TPSARRDLAE
1260 1270 1280 1290 1300
EIVMYMNNMS SPLTSRTPSI DLQRACDDKL NKKSPPLVKA CRRSSLPPNS
1310 1320 1330 1340 1350
PKPVRLTKSK SYTKSEEKPR DRLWSSPAFS PTCPFREESQ DTLTHSSPSF
1360 1370 1380 1390 1400
NLDTLLVPKL DVLRNSMFTA GKGVAEKASK WYSRFTMYTT SSKDQSSDRT
1410 1420 1430 1440 1450
SLSSVGAQDS ESTSLTDEDV CHELEGPISS QETSATSGTK RIDLSRISLE
1460 1470 1480 1490 1500
SSASLEGSLS KFALPGKSEV TSSFNASNTN IFQNYAMEVL ISSCSRCRTC
1510 1520 1530 1540 1550
DCLVHDEEIM AGWTADDSNL NTTCPFCGNI FLPFLNIEIR DLRRPGRYFL
1560 1570 1580 1590 1600
KSSPSTENMH FPSSISSQTR QSCISTSASG LDTSALSVQG NFDLNSKSKL
1610 1620 1630 1640 1650
QENFCTRSIQ IPANRSKTAM SKCPIFPMAR SISTSGPLDK EDTGRQKLIS
1660 1670 1680 1690 1700
TGSLPATLQG ATDSLGLEWH LPSPDPVTVP YLSPLVVWKE LESLLENEGD
1710 1720 1730 1740 1750
HAITVADFVD HHPIVFWNLV WYFRRLDLPS NLPGLILSSE HCNKYSKIPR
1760 1770 1780 1790 1800
HCMSEDSKYV LIQMLWDNMK LHQDPGQPLY ILWNAHSQSR TLLFETQKYP
1810 1820 1830 1840 1850
MVHLLQKSDN SFNQELLKSM VKSIKMNDVY GPMSQILETL NKCPHFKRQR
1860 1870 1880 1890 1900
SLYREILFLS LVALGRENID IDAFDKEYKM AYDRLTPSQV KSTHNCDRPP
1910
STGVMECRKT FGEPYL
Length:1,916
Mass (Da):214,837
Last modified:February 17, 2016 - v1
Checksum:i3ECFF0C34156ECAF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC011939 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000635620; ENSP00000489304; ENSG00000174485

Similar proteinsi

Entry informationi

Entry nameiA0A0U1RR27_HUMAN
AccessioniPrimary (citable) accession number: A0A0U1RR27
Entry historyiIntegrated into UniProtKB/TrEMBL: February 17, 2016
Last sequence update: February 17, 2016
Last modified: June 20, 2018
This is version 22 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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