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Protein
Submitted name:

Probable global transcription activator SNF2L2

Gene

SMARCA2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Probable global transcription activator SNF2L2Imported
Gene namesi
Name:SMARCA2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 9

Organism-specific databases

HGNCiHGNC:11098 SMARCA2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000080503

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 24Sequence analysisAdd BLAST24
ChainiPRO_500671435625 – 229Sequence analysisAdd BLAST205

Proteomic databases

PeptideAtlasiA0A0U1RQW7

Expressioni

Gene expression databases

ExpressionAtlasiA0A0U1RQW7 baseline and differential

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini105 – 175BromoInterPro annotationAdd BLAST71

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili38 – 58Sequence analysisAdd BLAST21
Coiled coili185 – 215Sequence analysisAdd BLAST31

Keywords - Domaini

BromodomainPROSITE-ProRule annotation, Coiled coilSequence analysis, SignalSequence analysis

Phylogenomic databases

GeneTreeiENSGT00550000074659

Family and domain databases

Gene3Di1.20.920.10, 1 hit
InterProiView protein in InterPro
IPR001487 Bromodomain
IPR036427 Bromodomain-like_sf
IPR018359 Bromodomain_CS
IPR030088 SMARCA2
PANTHERiPTHR10799:SF541 PTHR10799:SF541, 1 hit
PfamiView protein in Pfam
PF00439 Bromodomain, 1 hit
PRINTSiPR00503 BROMODOMAIN
SMARTiView protein in SMART
SM00297 BROMO, 1 hit
SUPFAMiSSF47370 SSF47370, 1 hit
PROSITEiView protein in PROSITE
PS00633 BROMODOMAIN_1, 1 hit
PS50014 BROMODOMAIN_2, 1 hit

Sequencei

Sequence statusi: Fragment.

A0A0U1RQW7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKRLAARCFA GLLILSPLTV ISDSRPADSG KAIEDGNLEE MEEEVRLKKR
60 70 80 90 100
KRRRNVDKDP AKEDVEKAKK RRGRPPAEKL SPNPPKLTKQ MNAIIDTVIN
110 120 130 140 150
YKDSSGRQLS EVFIQLPSRK ELPEYYELIR KPVDFKKIKE RIRNHKYRSL
160 170 180 190 200
GDLEKDVMLL CHNAQTFNLE GSQIYEDSIV LQSVFKSARQ KIAKEEESED
210 220
ESNEEEEEED EEESESEAKS VKVKIKLNK
Length:229
Mass (Da):26,501
Last modified:February 17, 2016 - v1
Checksum:i19FCA86AF78E97D7
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei229Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL138755 Genomic DNA No translation available.
AL359076 Genomic DNA No translation available.
AL591644 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000635530; ENSP00000489204; ENSG00000080503

Similar proteinsi

Entry informationi

Entry nameiA0A0U1RQW7_HUMAN
AccessioniPrimary (citable) accession number: A0A0U1RQW7
Entry historyiIntegrated into UniProtKB/TrEMBL: February 17, 2016
Last sequence update: February 17, 2016
Last modified: June 20, 2018
This is version 22 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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