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Entry version 35 (25 May 2022)
Sequence version 2 (05 Jun 2019)
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Protein
Submitted name:

Dystonin

Gene

DST

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionActin-bindingARBA annotation
LigandMetal-bindingARBA annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Dystonin
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:DST
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:1090, DST

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSG00000151914

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cytoplasm, CytoskeletonPROSITE-ProRule annotation

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000151914

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
A0A0U1RQJ2, baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
A0A0U1RQJ2

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini2303 – 2338EF-handInterPro annotationAdd BLAST36
Domaini2339 – 2374EF-handInterPro annotationAdd BLAST36
Domaini2379 – 2457GARInterPro annotationAdd BLAST79

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 22DisorderedSequence analysisAdd BLAST22
Regioni177 – 201DisorderedSequence analysisAdd BLAST25
Regioni2464 – 2485DisorderedSequence analysisAdd BLAST22
Regioni2501 – 2558DisorderedSequence analysisAdd BLAST58
Regioni2587 – 2676DisorderedSequence analysisAdd BLAST90

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili1300 – 1327Sequence analysisAdd BLAST28
Coiled coili1358 – 1378Sequence analysisAdd BLAST21
Coiled coili1406 – 1450Sequence analysisAdd BLAST45
Coiled coili1552 – 1590Sequence analysisAdd BLAST39
Coiled coili1679 – 1699Sequence analysisAdd BLAST21
Coiled coili2061 – 2091Sequence analysisAdd BLAST31
Coiled coili2269 – 2289Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi2467 – 2484Polar residuesSequence analysisAdd BLAST18
Compositional biasi2517 – 2552Polar residuesSequence analysisAdd BLAST36
Compositional biasi2621 – 2667Polar residuesSequence analysisAdd BLAST47

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000155008

Identification of Orthologs from Complete Genome Data

More...
OMAi
LQSCEIE

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00051, EFh, 1 hit
cd00176, SPEC, 11 hits

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.920.20, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011992, EF-hand-dom_pair
IPR018247, EF_Hand_1_Ca_BS
IPR002048, EF_hand_dom
IPR003108, GAR_dom
IPR036534, GAR_dom_sf
IPR043197, Plakin
IPR018159, Spectrin/alpha-actinin
IPR002017, Spectrin_repeat

The PANTHER Classification System

More...
PANTHERi
PTHR23169, PTHR23169, 4 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13499, EF-hand_7, 1 hit
PF02187, GAS2, 1 hit
PF00435, Spectrin, 13 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00054, EFh, 2 hits
SM00243, GAS2, 1 hit
SM00150, SPEC, 17 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF143575, SSF143575, 1 hit
SSF47473, SSF47473, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00018, EF_HAND_1, 2 hits
PS50222, EF_HAND_2, 2 hits
PS51460, GAR, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 16 potential isoforms that are computationally mapped.Show allAlign All

A0A0U1RQJ2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGKPLSRPDC LRQNPPCVGK GEEEEDLNIE DCYVPQRSIY DTVRLNEQID
60 70 80 90 100
SGSKGSLSSR HFTDRTLPYS HRTLDVSSLC SNGALTSSSV FELRGREANK
110 120 130 140 150
LDEKMIFDAL KLNSDIIRTT GLPKAKSHAE KKEHRRSWRM FVPANFMDYA
160 170 180 190 200
NKSESSFVEP ADMSDAVTKA SKCRWGTNSL TSEEDDSGLC SPPAEREEKQ
210 220 230 240 250
GILTGDQSRI KSLSSTEDIL VTDQYRPFFS VNSISEQKIP LLSCQSAHPD
260 270 280 290 300
ENFKMILHDV SPLEEAKHVN GQREIHDENC CLQNNLKESP VKCDPLIMPR
310 320 330 340 350
NRENEHIFNL GEEDETYGPG ESQITAQSRE LLKDSPQDLD LSHTDLGESD
360 370 380 390 400
VDCGSTSLVE NVTLLTQYDS GECNIASKEE VEAPLSAQES EMLYKKFSLK
410 420 430 440 450
FVSARKKAAP RKTGAQAGIL DTVCNGFQLV QVFQKEEIEP LQGKQQDVNW
460 470 480 490 500
LGQGLIQSAA KSTSTQGLEH DLDDVNARWK TLNKKVAQRA AQLQEALLHC
510 520 530 540 550
GRFQDALESL LSWMVDTEEL VANQKPPSAE FKVVKAQIQE QKLLQRLLDD
560 570 580 590 600
RKSTVEVIKR EGEKIATTAE PADKVKILKQ LSLLDSRWEA LLNKAETRNR
610 620 630 640 650
QLEGISVVAQ QFHETLEPLN EWLTTIEKRL VNCEPIGTQA SKLEEQIAQH
660 670 680 690 700
KALEDDIINH NKHLHQAVSI GQSLKVLSSR EDKDMVQSKL DFSQVWYIEI
710 720 730 740 750
QEKSHSRSEL LQQALCNAKI FGEDEVELMN WLNEVHDKLS KLSVQDYSTE
760 770 780 790 800
GLWKQQSELR VLQEDILLRK QNVDQALLNG LELLKQTTGD EVLIIQDKLE
810 820 830 840 850
AIKARYKDIT KLSTDVAKTL EQALQLARRL HSTHEELCTW LDKVEVELLS
860 870 880 890 900
YETQVLKGEE ASQAQMRPKE LKKEAKNNKA LLDSLNEVSS ALLELVPWRA
910 920 930 940 950
REGLEKMVAE DNERYRLVSD TITQKVEEID AAILRSQQFD QAADAELSWI
960 970 980 990 1000
TETEKKLMSL GDIRLEQDQT SAQLQVQKTF TMEILRHKDI IDDLVKSGHK
1010 1020 1030 1040 1050
IMTACSEEEK QSMKKKLDKV LKNYDTICQI NSERYLQLER AQSLVNQFWE
1060 1070 1080 1090 1100
TYEELWPWLT ETQSIISQLP APALEYETLR QQQEEHRQLR ELIAEHKPHI
1110 1120 1130 1140 1150
DKMNKTGPQL LELSPGEGFS IQEKYVAADT LYSQIKEDVK KRAVALDEAI
1160 1170 1180 1190 1200
SQSTQFHDKI DQILESLERI VERLRQPPSI SAEVEKIKEQ ISENKNVSVD
1210 1220 1230 1240 1250
MEKLQPLYET LKQRGEEMIA RSGGTDKDIS AKAVQDKLDQ MVFIWENIHT
1260 1270 1280 1290 1300
LVEEREAKLL DVMELAEKFW CDHMSLIVTI KDTQDFIRDL EDPGIDPSVV
1310 1320 1330 1340 1350
KQQQEAAETI REEIDGLQEE LDIVINLGSE LIAACGEPDK PIVKKSIDEL
1360 1370 1380 1390 1400
NSAWDSLNKA WKDRIDKLEE AMQAAVQYQD GLQAVFDWVD IAGGKLASMS
1410 1420 1430 1440 1450
PIGTDLETVK QQIEELKQFK SEAYQQQIEM ERLNHQAELL LKKVTEESDK
1460 1470 1480 1490 1500
HTVQDPLMEL KLIWDSLEER IINRQHKLEG ALLALGQFQH ALDELLAWLT
1510 1520 1530 1540 1550
HTEGLLSEQK PVGGDPKAIE IELAKHHVLQ NDVLAHQSTV EAVNKAGNDL
1560 1570 1580 1590 1600
IESSAGEEAS NLQNKLEVLN QRWQNVLEKT EQRKQQLDGA LRQAKGFHGE
1610 1620 1630 1640 1650
IEDLQQWLTD TERHLLASKP LGGLPETAKE QLNVHMEVCA AFEAKEETYK
1660 1670 1680 1690 1700
SLMQKGQQML ARCPKSAETN IDQDINNLKE KWESVETKLN ERKTKLEEAL
1710 1720 1730 1740 1750
NLAMEFHNSL QDFINWLTQA EQTLNVASRP SLILDTVLFQ IDEHKVFANE
1760 1770 1780 1790 1800
VNSHREQIIE LDKTGTHLKY FSQKQDVVLI KNLLISVQSR WEKVVQRLVE
1810 1820 1830 1840 1850
RGRSLDDARK RAKQFHEAWS KLMEWLEESE KSLDSELEIA NDPDKIKTQL
1860 1870 1880 1890 1900
AQHKEFQKSL GAKHSVYDTT NRTGRSLKEK TSLADDNLKL DDMLSELRDK
1910 1920 1930 1940 1950
WDTICGKSVE RQNKLEEALL FSGQFTDALQ ALIDWLYRVE PQLAEDQPVH
1960 1970 1980 1990 2000
GDIDLVMNLI DNHKAFQKEL GKRTSSVQAL KRSARELIEG SRDDSSWVKV
2010 2020 2030 2040 2050
QMQELSTRWE TVCALSISKQ TRLEAALRQA EEFHSVVHAL LEWLAEAEQT
2060 2070 2080 2090 2100
LRFHGVLPDD EDALRTLIDQ HKEFMKKLEE KRAELNKATT MGDTVLAICH
2110 2120 2130 2140 2150
PDSITTIKHW ITIIRARFEE VLAWAKQHQQ RLASALAGLI AKQELLEALL
2160 2170 2180 2190 2200
AWLQWAETTL TDKDKEVIPQ EIEEVKALIA EHQTFMEEMT RKQPDVDKVT
2210 2220 2230 2240 2250
KTYKRRAADP SSLQSHIPVL DKGRAGRKRF PASSLYPSGS QTQIETKNPR
2260 2270 2280 2290 2300
VNLLVSKWQQ VWLLALERRR KLNDALDRLE ELREFANFDF DIWRKKYMRW
2310 2320 2330 2340 2350
MNHKKSRVMD FFRRIDKDQD GKITRQEFID GILSSKFPTS RLEMSAVADI
2360 2370 2380 2390 2400
FDRDGDGYID YYEFVAALHP NKDAYKPITD ADKIEDEVTR QVAKCKCAKR
2410 2420 2430 2440 2450
FQVEQIGDNK YRFFLGNQFG DSQQLRLVRI LRSTVMVRVG GGWMALDEFL
2460 2470 2480 2490 2500
VKNDPCRVHH HGSKMLRSES NSSITTTQPT IAKGRTNMEL REKFILADGA
2510 2520 2530 2540 2550
SQGMAAFRPR GRRSRPSSRG ASPNRSTSVS SQAAQAASPQ VPATTTPKGT
2560 2570 2580 2590 2600
PIQGSKLRLP GYLSGKGFHS GEDSGLITTA AARVRTQFAD SKKTPSRPGS
2610 2620 2630 2640 2650
RAGSKAGSRA SSRRGSDASD FDISEIQSVC SDVETVPQTH RPTPRAGSRP
2660 2670
STAKPSKIPT PQRKSPASKL DKSSKR
Length:2,676
Mass (Da):304,562
Last modified:June 5, 2019 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC2EF8336D5822174
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 16 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q03001DYST_HUMAN
Dystonin
DST BP230, BP240, BPAG1, DMH, DT
7,570Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8W9J4F8W9J4_HUMAN
Dystonin
DST
7,461Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9PHM6E9PHM6_HUMAN
Dystonin
DST
5,497Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F6QMI7F6QMI7_HUMAN
Dystonin
DST
5,537Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A7P0T890A0A7P0T890_HUMAN
Dystonin
DST
7,818Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A494C073A0A494C073_HUMAN
Dystonin
DST
1,347Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A494C1U5A0A494C1U5_HUMAN
Dystonin
DST
625Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q5T0V7Q5T0V7_HUMAN
Dystonin
DST
689Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A494C1D7A0A494C1D7_HUMAN
Dystonin
DST
2,383Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q6P0N6Q6P0N6_HUMAN
DST protein
DST
1,143Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
There are more potential isoformsShow all

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AL096710 Genomic DNA No translation available.
AL137008 Genomic DNA No translation available.
AL512422 Genomic DNA No translation available.
AL512448 Genomic DNA No translation available.
AL590005 Genomic DNA No translation available.
AL590037 Genomic DNA No translation available.
KF458172 Genomic DNA No translation available.

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000340834.10; ENSP00000489032.2; ENSG00000151914.22

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL096710 Genomic DNA No translation available.
AL137008 Genomic DNA No translation available.
AL512422 Genomic DNA No translation available.
AL512448 Genomic DNA No translation available.
AL590005 Genomic DNA No translation available.
AL590037 Genomic DNA No translation available.
KF458172 Genomic DNA No translation available.

3D structure databases

SMRiA0A0U1RQJ2
ModBaseiSearch...

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
31066, 184 antibodies from 22 providers

Genome annotation databases

EnsembliENST00000340834.10; ENSP00000489032.2; ENSG00000151914.22

Organism-specific databases

HGNCiHGNC:1090, DST
OpenTargetsiENSG00000151914
VEuPathDBiHostDB:ENSG00000151914

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

GeneTreeiENSGT00940000155008
OMAiLQSCEIE

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
DST, human

Gene expression databases

ExpressionAtlasiA0A0U1RQJ2, baseline and differential

Family and domain databases

CDDicd00051, EFh, 1 hit
cd00176, SPEC, 11 hits
Gene3Di3.30.920.20, 1 hit
InterProiView protein in InterPro
IPR011992, EF-hand-dom_pair
IPR018247, EF_Hand_1_Ca_BS
IPR002048, EF_hand_dom
IPR003108, GAR_dom
IPR036534, GAR_dom_sf
IPR043197, Plakin
IPR018159, Spectrin/alpha-actinin
IPR002017, Spectrin_repeat
PANTHERiPTHR23169, PTHR23169, 4 hits
PfamiView protein in Pfam
PF13499, EF-hand_7, 1 hit
PF02187, GAS2, 1 hit
PF00435, Spectrin, 13 hits
SMARTiView protein in SMART
SM00054, EFh, 2 hits
SM00243, GAS2, 1 hit
SM00150, SPEC, 17 hits
SUPFAMiSSF143575, SSF143575, 1 hit
SSF47473, SSF47473, 1 hit
PROSITEiView protein in PROSITE
PS00018, EF_HAND_1, 2 hits
PS50222, EF_HAND_2, 2 hits
PS51460, GAR, 1 hit

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A0U1RQJ2_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A0U1RQJ2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: February 17, 2016
Last sequence update: June 5, 2019
Last modified: May 25, 2022
This is version 35 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health

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