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Protein
Submitted name:

CREB-binding protein

Gene

Crebbp

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-MMU-1234158 Regulation of gene expression by Hypoxia-inducible Factor
R-MMU-201722 Formation of the beta-catenin:TCF transactivating complex
R-MMU-2122947 NOTCH1 Intracellular Domain Regulates Transcription
R-MMU-3134973 LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production
R-MMU-3371568 Attenuation phase
R-MMU-350054 Notch-HLH transcription pathway
R-MMU-400206 Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
R-MMU-5621575 CD209 (DC-SIGN) signaling
R-MMU-8866907 Activation of the TFAP2 (AP-2) family of transcription factors
R-MMU-8939246 RUNX1 regulates transcription of genes involved in differentiation of myeloid cells
R-MMU-8941856 RUNX3 regulates NOTCH signaling
R-MMU-9018519 Estrogen-dependent gene expression
R-MMU-918233 TRAF3-dependent IRF activation pathway
R-MMU-933541 TRAF6 mediated IRF7 activation

Names & Taxonomyi

Protein namesi
Submitted name:
CREB-binding proteinImported
Gene namesi
Name:CrebbpImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 16

Organism-specific databases

MGIiMGI:1098280 Crebbp

Expressioni

Gene expression databases

ExpressionAtlasiA0A0U1RPQ3 baseline and differential

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini25 – 104KIXInterPro annotationAdd BLAST80

Phylogenomic databases

GeneTreeiENSGT00920000148952

Family and domain databases

InterProiView protein in InterPro
IPR003101 KIX_dom
IPR036529 KIX_dom_sf
PfamiView protein in Pfam
PF02172 KIX, 1 hit
SUPFAMiSSF47040 SSF47040, 1 hit
PROSITEiView protein in PROSITE
PS50952 KIX, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All

A0A0U1RPQ3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
XDGSNSGNIG SLSTIPTAAP PSSTGVRKGW HEHVTQDLRS HLVHKLVQAI
60 70 80 90 100
FPTPDPAALK DRRMENLVAY AKKVEGDMYE SANSRDEYYH LLAEKIYKIQ
110 120 130 140 150
KELEEKRRSR LHKQGILGNQ PALPASGAQP PVIPPAQSVR PPRMNSFNPM
160 170 180 190 200
SLGNVQLPQA PMGPRAASPM NHSVQMNSMA SVPGMAISPS RMPQPPNMMG
210 220 230 240
THANNIMAQA PTQNQFLPQN QFPSSSGAMS VNSVGMGQPA AQAGVSQ
Length:247
Mass (Da):26,595
Last modified:February 17, 2016 - v1
Checksum:iF7CF60C217A19186
GO

Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P45481CBP_MOUSE
CREB-binding protein
Crebbp Cbp
2,441Annotation score:
F8VPR5F8VPR5_MOUSE
CREB-binding protein
Crebbp
2,441Annotation score:
A0A0U1RQB6A0A0U1RQB6_MOUSE
CREB-binding protein
Crebbp
2,403Annotation score:
A0A0U1RPL2A0A0U1RPL2_MOUSE
CREB-binding protein
Crebbp
1,107Annotation score:
A0A0U1RP23A0A0U1RP23_MOUSE
CREB-binding protein
Crebbp
172Annotation score:
A0A0U1RP46A0A0U1RP46_MOUSE
CREB-binding protein
Crebbp
127Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei247Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC132380 Genomic DNA No translation available.
AC132575 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSMUST00000205685; ENSMUSP00000146076; ENSMUSG00000022521

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC132380 Genomic DNA No translation available.
AC132575 Genomic DNA No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000205685; ENSMUSP00000146076; ENSMUSG00000022521

Organism-specific databases

MGIiMGI:1098280 Crebbp

Phylogenomic databases

GeneTreeiENSGT00920000148952

Enzyme and pathway databases

ReactomeiR-MMU-1234158 Regulation of gene expression by Hypoxia-inducible Factor
R-MMU-201722 Formation of the beta-catenin:TCF transactivating complex
R-MMU-2122947 NOTCH1 Intracellular Domain Regulates Transcription
R-MMU-3134973 LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production
R-MMU-3371568 Attenuation phase
R-MMU-350054 Notch-HLH transcription pathway
R-MMU-400206 Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
R-MMU-5621575 CD209 (DC-SIGN) signaling
R-MMU-8866907 Activation of the TFAP2 (AP-2) family of transcription factors
R-MMU-8939246 RUNX1 regulates transcription of genes involved in differentiation of myeloid cells
R-MMU-8941856 RUNX3 regulates NOTCH signaling
R-MMU-9018519 Estrogen-dependent gene expression
R-MMU-918233 TRAF3-dependent IRF activation pathway
R-MMU-933541 TRAF6 mediated IRF7 activation

Miscellaneous databases

ChiTaRSiCrebbp mouse
SOURCEiSearch...

Gene expression databases

ExpressionAtlasiA0A0U1RPQ3 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR003101 KIX_dom
IPR036529 KIX_dom_sf
PfamiView protein in Pfam
PF02172 KIX, 1 hit
SUPFAMiSSF47040 SSF47040, 1 hit
PROSITEiView protein in PROSITE
PS50952 KIX, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A0U1RPQ3_MOUSE
AccessioniPrimary (citable) accession number: A0A0U1RPQ3
Entry historyiIntegrated into UniProtKB/TrEMBL: February 17, 2016
Last sequence update: February 17, 2016
Last modified: September 12, 2018
This is version 18 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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