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UniProtKB - A0A0T9WNE3 (A0A0T9WNE3_MYCTX)

Entry version 35 (13 Nov 2019)
Sequence version 1 (17 Feb 2016)
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Protein
Submitted name:

Dehydrogenase

Gene

DSI35_28165

Organism
Mycobacterium tuberculosis
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionOxidoreductaseImported

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
DehydrogenaseImported (EC:1.-.-.-Imported)
Submitted name:
FAD-binding oxidoreductaseImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:DSI35_28165Imported, ERS007661_00081Imported, ERS007663_02708Imported, ERS007670_00375Imported, ERS007672_00332Imported, ERS007679_00171Imported, ERS023446_00319Imported, ERS024276_02460Imported, ERS027651_00076Imported, ERS027653_01259Imported, ERS027654_01165Imported, ERS027656_01020Imported, ERS027661_00339Imported, ERS027666_00098Imported, ERS124361_02650Imported, EZX46_16295Imported, FDK60_20170Imported, SAMEA2682835_04610Imported, SAMEA2682864_00395Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMycobacterium tuberculosisImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri1773 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteria › Actinobacteria › Corynebacteriales › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000256252 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence
  • UP000298273 Componenti: Unassembled WGS sequence
  • UP000047075 Componenti: Unassembled WGS sequence
  • UP000298647 Componenti: Unassembled WGS sequence
  • UP000049023 Componenti: Unassembled WGS sequence
  • UP000183655 Componenti: Unassembled WGS sequence
  • UP000039953 Componenti: Unassembled WGS sequence
  • UP000305204 Componenti: Unassembled WGS sequence
  • UP000049258 Componenti: Unassembled WGS sequence
  • UP000050143 Componenti: Unassembled WGS sequence
  • UP000049114 Componenti: Unassembled WGS sequence
  • UP000049058 Componenti: Unassembled WGS sequence

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini35 – 214FAD-binding PCMH-typeInterPro annotationAdd BLAST180

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni28 – 47DisorderedSequence analysisAdd BLAST20

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.10.45.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR016166 FAD-bd_PCMH
IPR036318 FAD-bd_PCMH-like_sf
IPR016164 FAD-linked_Oxase-like_C
IPR004113 FAD-linked_oxidase_C
IPR006094 Oxid_FAD_bind_N
IPR016171 Vanillyl_alc_oxidase_C-sub2

Pfam protein domain database

More...Pfami		View protein in Pfam
PF02913 FAD-oxidase_C, 1 hit
PF01565 FAD_binding_4, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF55103 SSF55103, 1 hit
SSF56176 SSF56176, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS51387 FAD_PCMH, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A0T9WNE3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSEMTARFSE IVGNANLLTG DAIPEDYAHD EELTGPPQKP AYAAKPATPE 
        60         70         80         90        100
EVAQLLKAAS ENGVPVTARG SGCGLSGAAR PVEGGLLISF DRMNKVLEVD 
       110        120        130        140        150
TANQVAVVQP GVALTDLDAA TADTGLRYTV YPGELSSSVG GNVGTNAGGM 
       160        170        180        190        200
RAVKYGVARH NVLGLQAVLP TGEIIRTGGR MAKVSTGYDL TQLIIGSEGT 
       210        220        230        240        250
LALVTEVIVK LHPRLDHNAS VLAPFADFDQ VMAAVPKILA SGLAPDILEY 
       260        270        280        290        300
IDNTSMAALI STQNLELGIP DQIRDSCEAY LLVALENRIA DRLFEDIQTV 
       310        320        330        340        350
GEMLMELGAV DAYVLEGGSA RKLIEAREKA FWAAKALGAD DIIDTVVPRA 
       360        370        380        390        400
SMPKFLSTAR GLAAAADGAA VGCGHAGDGN VHMAIACKDP EKKKKLMTDI 
       410        420        430        440        450
FALAMELGGA ISGEHGVGRA KTGYFLELED PVKISLMRRI KQSFDPAGIL 

NPGVVFGDT
Length:459
Mass (Da):48,052
Last modified:February 17, 2016 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i5301BAD1396B4B0F
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
CNCN01000656 Genomic DNA Translation: CKP13396.1
CNFU01000037 Genomic DNA Translation: CKQ94994.1
CNFV01000119 Genomic DNA Translation: CKR31158.1
CNFR01000180 Genomic DNA Translation: CKR35984.1
CIEA01000001 Genomic DNA Translation: CKR36249.1
CNFS01000228 Genomic DNA Translation: CKR41212.1
CNGG01000011 Genomic DNA Translation: CKR85560.1
CHDS01000050 Genomic DNA Translation: CNH03186.1
CQGE01000004 Genomic DNA Translation: CNM43340.1
CQPL01000047 Genomic DNA Translation: CNT86787.1
CQQC01000011 Genomic DNA Translation: CNU11010.1
CQPV01000449 Genomic DNA Translation: CNV24749.1
CSAD01000010 Genomic DNA Translation: COU69281.1
CHEE01000033 Genomic DNA Translation: COU76439.1
QSXG01002148 Genomic DNA Translation: REM95899.1
FPPU01000022 Genomic DNA Translation: SGD65163.1
FPXX01000002 Genomic DNA Translation: SGL44442.1
SMOE01000097 Genomic DNA Translation: TFB19031.1
SZTS01000101 Genomic DNA Translation: TKR36159.1

NCBI Reference Sequences

More...RefSeqi		WP_003411690.1, NZ_VOOP01000041.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...EnsemblBacteriai		AMC46708; AMC46708; RN05_2432
CKP13396; CKP13396; ERS024276_02460
CKQ94994; CKQ94994; ERS027661_00339
CKR31158; CKR31158; ERS027656_01020
CKR35984; CKR35984; ERS027654_01165
CKR41212; CKR41212; ERS027653_01259
CKR85560; CKR85560; ERS027666_00098
CNH03186; CNH03186; ERS124361_02650
CNM43340; CNM43340; ERS023446_00319
CNT86787; CNT86787; ERS007670_00375
CNU11010; CNU11010; ERS007661_00081
CNV24749; CNV24749; ERS007663_02708
CNY83142; CNY83142; ERS013471_02810
COU69281; COU69281; ERS007679_00171
COU76439; COU76439; ERS007672_00332

Pathosystems Resource Integration Center (PATRIC)

More...PATRICi		fig|1773.206.peg.1616

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CNCN01000656 Genomic DNA Translation: CKP13396.1
CNFU01000037 Genomic DNA Translation: CKQ94994.1
CNFV01000119 Genomic DNA Translation: CKR31158.1
CNFR01000180 Genomic DNA Translation: CKR35984.1
CIEA01000001 Genomic DNA Translation: CKR36249.1
CNFS01000228 Genomic DNA Translation: CKR41212.1
CNGG01000011 Genomic DNA Translation: CKR85560.1
CHDS01000050 Genomic DNA Translation: CNH03186.1
CQGE01000004 Genomic DNA Translation: CNM43340.1
CQPL01000047 Genomic DNA Translation: CNT86787.1
CQQC01000011 Genomic DNA Translation: CNU11010.1
CQPV01000449 Genomic DNA Translation: CNV24749.1
CSAD01000010 Genomic DNA Translation: COU69281.1
CHEE01000033 Genomic DNA Translation: COU76439.1
QSXG01002148 Genomic DNA Translation: REM95899.1
FPPU01000022 Genomic DNA Translation: SGD65163.1
FPXX01000002 Genomic DNA Translation: SGL44442.1
SMOE01000097 Genomic DNA Translation: TFB19031.1
SZTS01000101 Genomic DNA Translation: TKR36159.1
RefSeqiWP_003411690.1, NZ_VOOP01000041.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Genome annotation databases

EnsemblBacteriaiAMC46708; AMC46708; RN05_2432
CKP13396; CKP13396; ERS024276_02460
CKQ94994; CKQ94994; ERS027661_00339
CKR31158; CKR31158; ERS027656_01020
CKR35984; CKR35984; ERS027654_01165
CKR41212; CKR41212; ERS027653_01259
CKR85560; CKR85560; ERS027666_00098
CNH03186; CNH03186; ERS124361_02650
CNM43340; CNM43340; ERS023446_00319
CNT86787; CNT86787; ERS007670_00375
CNU11010; CNU11010; ERS007661_00081
CNV24749; CNV24749; ERS007663_02708
CNY83142; CNY83142; ERS013471_02810
COU69281; COU69281; ERS007679_00171
COU76439; COU76439; ERS007672_00332
PATRICifig|1773.206.peg.1616

Family and domain databases

Gene3Di1.10.45.10, 1 hit
InterProiView protein in InterPro
IPR016166 FAD-bd_PCMH
IPR036318 FAD-bd_PCMH-like_sf
IPR016164 FAD-linked_Oxase-like_C
IPR004113 FAD-linked_oxidase_C
IPR006094 Oxid_FAD_bind_N
IPR016171 Vanillyl_alc_oxidase_C-sub2
PfamiView protein in Pfam
PF02913 FAD-oxidase_C, 1 hit
PF01565 FAD_binding_4, 1 hit
SUPFAMiSSF55103 SSF55103, 1 hit
SSF56176 SSF56176, 1 hit
PROSITEiView protein in PROSITE
PS51387 FAD_PCMH, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A0T9WNE3_MYCTX
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A0T9WNE3
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: February 17, 2016
Last sequence update: February 17, 2016
Last modified: November 13, 2019
This is version 35 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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