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Protein

Chromosomal replication initiator protein DnaA

Gene

dnaA

Organism
Parcubacteria bacterium DG_74_2
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.UniRule annotationSAAS annotation

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi152 – 159ATPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingUniRule annotationSAAS annotation
Biological processDNA replicationUniRule annotationSAAS annotation
LigandATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Chromosomal replication initiator protein DnaAUniRule annotationSAAS annotation
Gene namesi
Name:dnaAUniRule annotation
ORF Names:AMJ49_00365Imported
OrganismiParcubacteria bacterium DG_74_2Imported
Taxonomic identifieri1703766 [NCBI]
Taxonomic lineageiBacteriaCandidatus Parcubacteria
Proteomesi
  • UP000051668 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini144 – 289AAAInterPro annotationAdd BLAST146
Domaini355 – 423Bac_DnaA_CInterPro annotationAdd BLAST69

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili423 – 443Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the DnaA family.UniRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysis

Family and domain databases

CDDicd06571 Bac_DnaA_C, 1 hit
Gene3Di1.10.1750.10, 1 hit
3.30.300.180, 1 hit
HAMAPiMF_00377 DnaA_bact, 1 hit
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR001957 Chromosome_initiator_DnaA
IPR020591 Chromosome_initiator_DnaA-like
IPR018312 Chromosome_initiator_DnaA_CS
IPR013317 DnaA
IPR013159 DnaA_C
IPR024633 DnaA_N_dom
IPR038454 DnaA_N_sf
IPR027417 P-loop_NTPase
IPR010921 Trp_repressor/repl_initiator
PANTHERiPTHR30050:SF2 PTHR30050:SF2, 1 hit
PfamiView protein in Pfam
PF00308 Bac_DnaA, 1 hit
PF08299 Bac_DnaA_C, 1 hit
PF11638 DnaA_N, 1 hit
PRINTSiPR00051 DNAA
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SM00760 Bac_DnaA_C, 1 hit
SUPFAMiSSF48295 SSF48295, 1 hit
SSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00362 DnaA, 1 hit
PROSITEiView protein in PROSITE
PS01008 DNAA, 1 hit

Sequencei

Sequence statusi: Complete.

A0A0S7X6L9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEKEELWQSV LAQIQLNISP ANFTTWFKNT NVISLKEGEV LISAPSSFVK
60 70 80 90 100
EWLEQKYNKL ILKILRSLDQ KIKEVKYIVG KNKPKSLKKL PSFLEIGQLE
110 120 130 140 150
FQEFKANRET NLNPRYTFEN FIVGSFNELA YAAAKAVCEN PGFVYNPLFV
160 170 180 190 200
YGGVGLGKTH LLEAVGNEIV KKFPQRKVKY IPSENLVSQI VDSIRKREID
210 220 230 240 250
NFKLKVQEVD VLVVDDVQFL SGKEKTQEEF FHIFNNLYAK NKQIVLSSDK
260 270 280 290 300
PPRALQYLTE RLKSRFEGGM IADISQPDLE TRIAILKEKS SERKFEFPES
310 320 330 340 350
ILNYIASNIT QNIRRLEGAL NRMATYQKLN GKVPDLEIVK ILLKDIIISP
360 370 380 390 400
NKVITPKKII QATAEFYDLK EKDLLSKSRR KEIVKPRQIA MYLLRKELKG
410 420 430 440
SFPFIGRKLK KDHTTVIYAF EKISKTIEKN EDLNQEINMI KERISSF
Length:447
Mass (Da):51,749
Last modified:February 17, 2016 - v1
Checksum:i3910EE8C37CF939B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LJNF01000001 Genomic DNA Translation: KPJ57564.1

Genome annotation databases

PATRICifig|1703766.3.peg.744

Similar proteinsi

Entry informationi

Entry nameiA0A0S7X6L9_9BACT
AccessioniPrimary (citable) accession number: A0A0S7X6L9
Entry historyiIntegrated into UniProtKB/TrEMBL: February 17, 2016
Last sequence update: February 17, 2016
Last modified: July 18, 2018
This is version 19 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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