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Entry version 10 (11 Dec 2019)
Sequence version 1 (17 Feb 2016)
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Protein
Submitted name:

IF4G1

Gene

IF4G1

Organism
Poeciliopsis prolifica (blackstripe livebearer)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
IF4G1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:IF4G1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPoeciliopsis prolifica (blackstripe livebearer)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri188132 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataOvalentariaAtherinomorphaeCyprinodontiformesPoeciliidaePoeciliinaePoeciliopsis

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini770 – 971MIF4GInterPro annotationAdd BLAST202

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 84DisorderedSequence analysisAdd BLAST84
Regioni161 – 228DisorderedSequence analysisAdd BLAST68
Regioni247 – 324DisorderedSequence analysisAdd BLAST78
Regioni339 – 398DisorderedSequence analysisAdd BLAST60
Regioni411 – 631DisorderedSequence analysisAdd BLAST221
Regioni692 – 719DisorderedSequence analysisAdd BLAST28

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili872 – 899Sequence analysisAdd BLAST28

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1 – 18Pro-richSequence analysisAdd BLAST18
Compositional biasi49 – 69PolarSequence analysisAdd BLAST21
Compositional biasi169 – 184Pro-richSequence analysisAdd BLAST16
Compositional biasi191 – 205PolyampholyteSequence analysisAdd BLAST15
Compositional biasi212 – 228PolarSequence analysisAdd BLAST17
Compositional biasi286 – 323PolarSequence analysisAdd BLAST38
Compositional biasi339 – 359PolarSequence analysisAdd BLAST21
Compositional biasi367 – 391PolyampholyteSequence analysisAdd BLAST25
Compositional biasi414 – 439PolarSequence analysisAdd BLAST26
Compositional biasi469 – 490PolarSequence analysisAdd BLAST22
Compositional biasi520 – 544PolarSequence analysisAdd BLAST25
Compositional biasi545 – 568PolyampholyteSequence analysisAdd BLAST24
Compositional biasi588 – 631PolyampholyteSequence analysisAdd BLAST44

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.40.180, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR016024, ARM-type_fold
IPR037584, EIF4G1
IPR016021, MIF4-like_sf
IPR003890, MIF4G-like_typ-3

The PANTHER Classification System

More...
PANTHERi
PTHR23253:SF10, PTHR23253:SF10, 1 hit

Pfam protein domain database

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Pfami
View protein in Pfam
PF02854, MIF4G, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00543, MIF4G, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48371, SSF48371, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A0S7K5L4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNKPPQPITG PTSVPNPSPS PGLTQAAFGP GQPPSLVFAT PPPPQMNSAQ
60 70 80 90 100
QPRQSYYQSR ATLAASAPRV QASSGPRPVA PTHVYPTGSQ MMMIPQQQIP
110 120 130 140 150
FGGSPQGYFI PPGQYRTSYM PPTQQYPVTS GTGFYPGTSP AEYSAYAGAY
160 170 180 190 200
YPAQPQYSPS VQPAPVMINP QQQAPPPQQA PTQPQAPPKR ERKQITIRDP
210 220 230 240 250
NQGGRDITKE IMSGGRSTTA ATPPQASVAE VSVAQTNGEV VQTVAVVTRR
260 270 280 290 300
DEPVEPSVSP ESPPPAAPAS TDLVVEAKQE VNRQFTPPVE LATQSVATTA
310 320 330 340 350
TSERLSPSLK ERQSPTSLPS AAEGISSVAE AVTLVSLKAS DTVDSPVRPS
360 370 380 390 400
ASPGAQETPV KTEEPQAAPS AEEEVKPEGI QLEKEEVTAS AKSEPPVEVA
410 420 430 440 450
VIPVEIVKED AAVKPSSNVS QPLTVPEPAV SQAEDADQSS EPEQVAVRPA
460 470 480 490 500
ESPLSNGLPQ ETEELSEDVP VSDTTPQDKP DPSQSQESAT PAQKDEEEEK
510 520 530 540 550
EQDEEEESRE EERPQKKTED ASLASATCPE ETTMQAATSV PKKRKSMNEL
560 570 580 590 600
NKKAILDAFK EEPDAKPVPE PSEVQVSPPA PAKPPAETVD ETWKEKEDKQ
610 620 630 640 650
DAEPDKLKST LEPTEQKYQY KEDLGEPINP EAKKRYDREF LLGFQFSSAS
660 670 680 690 700
MHKPEGLPVI SDVVLDEVNK TPLRPIDPSR LMSAGSDFTP TFLGGLGGKS
710 720 730 740 750
AGRPQPSGSH RSQQSLRKEP KKIIIFNSRS LTDSVQLNKA ANAWKPSTIK
760 770 780 790 800
PEESNSKEAD TEQAKTQEVF KRLRSILNKL TPQKFQELMK QVMELKIDTE
810 820 830 840 850
ERLKGTIDLV FEKAISEPNF SVAYANMCRC LIGLKVPIPD KPGNFVNFRK
860 870 880 890 900
LLLNRCQKEF EKDQDDDEIF EKKQKEMEAS KNDEERERLR VELEEARDKA
910 920 930 940 950
RRRSLGNIKF IGELFKLKML TEAIMHDCVV KLLKNHDEES LECLCRLLST
960 970
IGKDLDFEKA KVSWLSTCAE GSG
Length:973
Mass (Da):106,330
Last modified:February 17, 2016 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iEFF74196CC05B1D2
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
GBYX01220031 Transcribed RNA Translation: JAO72622.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GBYX01220031 Transcribed RNA Translation: JAO72622.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Family and domain databases

Gene3Di1.25.40.180, 1 hit
InterProiView protein in InterPro
IPR016024, ARM-type_fold
IPR037584, EIF4G1
IPR016021, MIF4-like_sf
IPR003890, MIF4G-like_typ-3
PANTHERiPTHR23253:SF10, PTHR23253:SF10, 1 hit
PfamiView protein in Pfam
PF02854, MIF4G, 1 hit
SMARTiView protein in SMART
SM00543, MIF4G, 1 hit
SUPFAMiSSF48371, SSF48371, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A0S7K5L4_9TELE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A0S7K5L4
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: February 17, 2016
Last sequence update: February 17, 2016
Last modified: December 11, 2019
This is version 10 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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