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Protein
Submitted name:

ROCK1

Gene

ROCK1

Organism
Poeciliopsis prolifica (blackstripe livebearer)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandMetal-bindingSAAS annotation, ZincSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
ROCK1Imported
Gene namesi
Name:ROCK1Imported
OrganismiPoeciliopsis prolifica (blackstripe livebearer)Imported
Taxonomic identifieri188132 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataOvalentariaAtherinomorphaeCyprinodontiformesPoeciliidaePoeciliinaePoeciliopsis

Subcellular locationi

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini412 – 611PHInterPro annotationAdd BLAST200
Domaini522 – 577Phorbol-ester/DAG-typeInterPro annotationAdd BLAST56

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili36 – 70Sequence analysisAdd BLAST35
Coiled coili85 – 133Sequence analysisAdd BLAST49
Coiled coili141 – 182Sequence analysisAdd BLAST42
Coiled coili229 – 270Sequence analysisAdd BLAST42
Coiled coili312 – 399Sequence analysisAdd BLAST88

Keywords - Domaini

Coiled coilSequence analysis

Family and domain databases

CDDicd00029 C1, 1 hit
Gene3Di2.30.29.30, 1 hit
InterProiView protein in InterPro
IPR002219 PE/DAG-bd
IPR011993 PH-like_dom_sf
IPR001849 PH_domain
IPR015008 Rho-bd_dom
IPR029876 ROCK1
PANTHERiPTHR22988:SF33 PTHR22988:SF33, 1 hit
PfamiView protein in Pfam
PF08912 Rho_Binding, 1 hit
SMARTiView protein in SMART
SM00109 C1, 1 hit
SM00233 PH, 1 hit
PROSITEiView protein in PROSITE
PS50003 PH_DOMAIN, 1 hit
PS50081 ZF_DAG_PE_2, 1 hit

Sequencei

Sequence statusi: Complete.

A0A0S7FMZ4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MIAVQHKMSE ETGARIRAEG RVVEVEKQCS MLEFDLKQSV QKMEQLMKQK
60 70 80 90 100
ERLEDEVKGL HTHLDQESSK RVAAQNDLKS RTQDVDRLRC SEKQLKQEIN
110 120 130 140 150
TALESKRSLE FQLAQLTKQY RGNEGQMREL QDQLEAEQYF STLYKTQVRE
160 170 180 190 200
LKEEIEERNR QVQEAQKKVH DLISERDSLS AQLDLTVTKA ESEQLARALQ
210 220 230 240 250
EEQYFELSQE NKKATARHKQ EIGEREATIA QLEESNKTLT KDVEHLSKNN
260 270 280 290 300
TELSEKLRLQ EEEYLSQKEE ITASAKAHYE KVLQTERTLK TQAVNKLAEI
310 320 330 340 350
MNRKDMKLDQ KKKGSTAELR KKEKENRKLQ QELNQEKEKF NHMAIKYQKE
360 370 380 390 400
VNEMQAQLVE ESTHRNELQM QLASKESDIE QLREKLSDLQ QRVENSSVTS
410 420 430 440 450
LQTDETDSNP ADSRLEGWLS IPNRANIKRY GWKKQYVVVS SKKILFYNDE
460 470 480 490 500
QDKEQSNPSM VLDIDKLFHV RPVTQGDVYR AETEEIPRIF QILYANEGEC
510 520 530 540 550
RKEADMEPVP QGEKTNCLAH KGHEFIPTLY HFPSNCEACA KPLWHVFKPP
560 570 580 590 600
PALECRRCHV KCHRDHLDKK EDVIAPCKVN YDVTTARDML LLAVTQEEQK
610 620 630 640
KWIGHLGKKI PKTPPSTFSR VSPRSMSTRS GPNQSFRKNP KSNTAKLS
Length:648
Mass (Da):75,460
Last modified:February 17, 2016 - v1
Checksum:i5AC2EFA5BE4CE8C1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GBYX01463131 Transcribed RNA Translation: JAO18463.1

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GBYX01463131 Transcribed RNA Translation: JAO18463.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

CDDicd00029 C1, 1 hit
Gene3Di2.30.29.30, 1 hit
InterProiView protein in InterPro
IPR002219 PE/DAG-bd
IPR011993 PH-like_dom_sf
IPR001849 PH_domain
IPR015008 Rho-bd_dom
IPR029876 ROCK1
PANTHERiPTHR22988:SF33 PTHR22988:SF33, 1 hit
PfamiView protein in Pfam
PF08912 Rho_Binding, 1 hit
SMARTiView protein in SMART
SM00109 C1, 1 hit
SM00233 PH, 1 hit
PROSITEiView protein in PROSITE
PS50003 PH_DOMAIN, 1 hit
PS50081 ZF_DAG_PE_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A0S7FMZ4_9TELE
AccessioniPrimary (citable) accession number: A0A0S7FMZ4
Entry historyiIntegrated into UniProtKB/TrEMBL: February 17, 2016
Last sequence update: February 17, 2016
Last modified: March 28, 2018
This is version 12 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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