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Protein
Submitted name:

Interferon gamma receptor 1 isoform 1

Gene

IFNGR1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
Interferon gamma receptor 1 isoform 1Imported
Gene namesi
Name:IFNGR1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei247 – 270HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 17Sequence analysisAdd BLAST17
ChainiPRO_500660827918 – 489Sequence analysisAdd BLAST472

Proteomic databases

PRIDEiA0A0S2Z3Y2

Expressioni

Gene expression databases

ExpressionAtlasiA0A0S2Z3Y2 baseline and differential

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliA0A0S2Z3Y2
SMRiA0A0S2Z3Y2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini10 – 112Fibronectin type-IIIInterPro annotationAdd BLAST103
Domaini161 – 317IFNGR1InterPro annotationAdd BLAST157

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

KOiK05132
OMAiNSYHSRN
PhylomeDBiA0A0S2Z3Y2

Family and domain databases

Gene3Di2.60.40.10, 2 hits
InterProiView protein in InterPro
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR013783 Ig-like_fold
IPR021126 Interferon_gamma_pox/mammal
IPR008355 Interferon_gamma_rcpt_asu
PANTHERiPTHR20859:SF5 PTHR20859:SF5, 1 hit
PfamiView protein in Pfam
PF07140 IFNGR1, 1 hit
PF01108 Tissue_fac, 1 hit
PRINTSiPR01777 INTERFERONGR
SUPFAMiSSF49265 SSF49265, 2 hits

Sequencei

Sequence statusi: Fragment.

A0A0S2Z3Y2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MALLFLLPLV MQGVSRAEMG TADLGPSSVP TPTNVTIESY NMNPIVYWEY
60 70 80 90 100
QIMPQVPVFT VEVKNYGVKN SEWIDACINI SHHYCNISDH VGDPSNSLWV
110 120 130 140 150
RVKARVGQKE SAYAKSEEFA VCRDGKIGPP KLDIRKEEKQ IMIDIFHPSV
160 170 180 190 200
FVNGDEQEVD YDPETTCYIR VYNVYVRMNG SEIQYKILTQ KEDDCDEIQC
210 220 230 240 250
QLAIPVSSLN SQYCVSAEGV LHVWGVTTEK SKEVCITIFN SSIKGSLWIP
260 270 280 290 300
VVAALLLFLV LSLVFICFYI KKINPLKEKS IILPKSLISV VRSATLETKP
310 320 330 340 350
ESKYVSLITS YQPFSLEKEV VCEEPLSPAT VPGMHTEDNP GKVEHTEELS
360 370 380 390 400
SITEVVTTEE NIPDVVPGSH LTPIERESSS PLSSNQSEPG SIALNSYHSR
410 420 430 440 450
NCSESDHSRN GFDTDSSCLE SHSSLSDSEF PPNNKGEIKT EGQELITVIK
460 470 480
APTSFGYDKP HVLVDLLVDD SGKESLIGYR PTEDSKEFS
Length:489
Mass (Da):54,405
Last modified:February 17, 2016 - v1
Checksum:iDCF9E574D8F47400
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei489Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KU178144 mRNA Translation: ALQ33602.1
RefSeqiNP_000407.1, NM_000416.2
UniGeneiHs.520414

Genome annotation databases

GeneIDi3459
KEGGihsa:3459

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KU178144 mRNA Translation: ALQ33602.1
RefSeqiNP_000407.1, NM_000416.2
UniGeneiHs.520414

3D structure databases

ProteinModelPortaliA0A0S2Z3Y2
SMRiA0A0S2Z3Y2
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiA0A0S2Z3Y2

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi3459
KEGGihsa:3459

Organism-specific databases

CTDi3459

Phylogenomic databases

KOiK05132
OMAiNSYHSRN
PhylomeDBiA0A0S2Z3Y2

Miscellaneous databases

ChiTaRSiIFNGR1 human

Gene expression databases

ExpressionAtlasiA0A0S2Z3Y2 baseline and differential

Family and domain databases

Gene3Di2.60.40.10, 2 hits
InterProiView protein in InterPro
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR013783 Ig-like_fold
IPR021126 Interferon_gamma_pox/mammal
IPR008355 Interferon_gamma_rcpt_asu
PANTHERiPTHR20859:SF5 PTHR20859:SF5, 1 hit
PfamiView protein in Pfam
PF07140 IFNGR1, 1 hit
PF01108 Tissue_fac, 1 hit
PRINTSiPR01777 INTERFERONGR
SUPFAMiSSF49265 SSF49265, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiA0A0S2Z3Y2_HUMAN
AccessioniPrimary (citable) accession number: A0A0S2Z3Y2
Entry historyiIntegrated into UniProtKB/TrEMBL: February 17, 2016
Last sequence update: February 17, 2016
Last modified: July 18, 2018
This is version 18 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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