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Protein
Submitted name:

ATP-binding cassette sub-family B member 7 isoform 1

Gene

ABCB7

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi506 – 513ATPPROSITE-ProRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandATP-bindingPROSITE-ProRule annotationImported, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
ATP-binding cassette sub-family B member 7 isoform 1Imported
Submitted name:
ATP-binding cassette, sub-family B (MDR/TAP), member 7, isoform CRA_eImported
Gene namesi
Name:ABCB7Imported
ORF Names:hCG_19369Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei141 – 166HelicalSequence analysisAdd BLAST26
Transmembranei186 – 207HelicalSequence analysisAdd BLAST22
Transmembranei261 – 288HelicalSequence analysisAdd BLAST28
Transmembranei294 – 315HelicalSequence analysisAdd BLAST22
Transmembranei384 – 406HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PRIDEiA0A0S2Z2Z3

Expressioni

Gene expression databases

ExpressionAtlasiA0A0S2Z2Z3 baseline and differential

Structurei

3D structure databases

SMRiA0A0S2Z2Z3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini142 – 437ABC transmembrane type-1InterPro annotationAdd BLAST296
Domaini473 – 707ABC transporterInterPro annotationAdd BLAST235

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili720 – 740Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

OMAiYEAQRYD

Family and domain databases

Gene3Di1.20.1560.10, 1 hit
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR011527 ABC1_TM_dom
IPR036640 ABC1_TM_sf
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00664 ABC_membrane, 1 hit
PF00005 ABC_tran, 1 hit
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
SSF90123 SSF90123, 1 hit
PROSITEiView protein in PROSITE
PS50929 ABC_TM1F, 1 hit
PS00211 ABC_TRANSPORTER_1, 1 hit
PS50893 ABC_TRANSPORTER_2, 1 hit

Sequencei

Sequence statusi: Fragment.

A0A0S2Z2Z3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALLAMHSWR WAAAAAAFEK RRHSAILIRP LVSVSGSGPQ WRPHQLGALG
60 70 80 90 100
TARAYQQIPE SLKSITWQRL GKGNSGQFLD AAKALQVWPL IEKRTCWHGH
110 120 130 140 150
AGGGLHTDPK EGLKDVDTRK IIKAMLSYVW PKDRPDLRAR VAISLGFLGG
160 170 180 190 200
AKAMNIVVPF MFKYAVDSLN QMSGNMLNLS DAPNTVATMA TAVLIGYGVS
210 220 230 240 250
RAGAAFFNEV RNAVFGKVAQ NSIRRIAKNV FLHLHNLDLG FHLSRQTGAL
260 270 280 290 300
SKAIDRGTRG ISFVLSALVF NLLPIMFEVM LVSGVLYYKC GAQFALVTLG
310 320 330 340 350
TLGTYTAFTV AVTRWRTRFR IEMNKADNDA GNAAIDSLLN YETVKYFNNE
360 370 380 390 400
RYEAQRYDGF LKTYETASLK STSTLAMLNF GQSAIFSVGL TAIMVLASQG
410 420 430 440 450
IVAGTLTVGD LVMVNGLLFQ LSLPLNFLGT VYRETRQALI DMNTLFTLLK
460 470 480 490 500
VDTQIKDKVM ASPLQITPQT ATVAFDNVHF EYIEGQKVLS GISFEVPAGK
510 520 530 540 550
KVAIVGGSGS GKSTIVRLLF RFYEPQKGSI YLAGQNIQDV SLESLRRAVG
560 570 580 590 600
VVPQDAVLFH NTIYYNLLYG NISASPEEVY AVAKLAGLHD AILRMPHGYD
610 620 630 640 650
TQVGERGLKL SGGEKQRVAI ARAILKDPPV ILYDEATSSL DSITEETILG
660 670 680 690 700
AMKDVVKHRT SIFIAHRLST VVDADEIIVL DQGKVAERGT HHGLLANPHS
710 720 730 740 750
IYSEMWHTQS SRVQNHDNPK WEAKKENISK EEERKKLQEE IVNSVKGCGN

CSC
Length:753
Mass (Da):82,769
Last modified:February 17, 2016 - v1
Checksum:i9B96042C55C3C62F
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei753Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KU177872 mRNA Translation: ALQ33330.1
CH471104 Genomic DNA Translation: EAW98636.1
RefSeqiNP_004290.2, NM_004299.4
UniGeneiHs.370480

Genome annotation databases

GeneIDi22

Similar proteinsi

Entry informationi

Entry nameiA0A0S2Z2Z3_HUMAN
AccessioniPrimary (citable) accession number: A0A0S2Z2Z3
Entry historyiIntegrated into UniProtKB/TrEMBL: February 17, 2016
Last sequence update: February 17, 2016
Last modified: May 23, 2018
This is version 22 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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