Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 48 (25 May 2022)
Sequence version 2 (20 Jun 2018)
Previous versions | rss
Add a publicationFeedback
Protein

Histone acetyltransferase

Gene

crebbpb

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei1438Acetyl-CoA; via carbonyl oxygenPROSITE-ProRule annotation1
Binding sitei1443Acetyl-CoAPROSITE-ProRule annotation1
Binding sitei1447Acetyl-CoAPROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri322 – 408TAZ-typePROSITE-ProRule annotationAdd BLAST87
Zinc fingeri1710 – 1791TAZ-typePROSITE-ProRule annotationAdd BLAST82

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionAcyltransferasePROSITE-ProRule annotationARBA annotation, Transferase
Biological processBiological rhythmsARBA annotation, Transcription, Transcription regulationARBA annotation
LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Histone acetyltransferaseARBA annotation (EC:2.3.1.48ARBA annotation)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:crebbpbImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7955 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesDanionidaeDanioninaeDanio
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000437 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3

Organism-specific databases

Zebrafish Information Network genome database

More...
ZFINi
ZDB-GENE-050302-102, crebbpb

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

CytoplasmARBA annotation, NucleusARBA annotation

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Keywords - PTMi

AcetylationARBA annotation, Isopeptide bondARBA annotation, MethylationARBA annotation, PhosphoproteinARBA annotation

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
A0A0R4IVZ7

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
7955.ENSDARP00000086306

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini322 – 408TAZ-typeInterPro annotationAdd BLAST87
Domaini550 – 629KIXInterPro annotationAdd BLAST80
Domaini1037 – 1109BromoInterPro annotationAdd BLAST73
Domaini1268 – 1645CBP/p300-type HATInterPro annotationAdd BLAST378
Domaini1646 – 1689ZZ-typeInterPro annotationAdd BLAST44
Domaini1710 – 1791TAZ-typeInterPro annotationAdd BLAST82

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 28DisorderedSequence analysisAdd BLAST28
Regioni88 – 147DisorderedSequence analysisAdd BLAST60
Regioni414 – 452DisorderedSequence analysisAdd BLAST39
Regioni506 – 529DisorderedSequence analysisAdd BLAST24
Regioni631 – 674DisorderedSequence analysisAdd BLAST44
Regioni809 – 1022DisorderedSequence analysisAdd BLAST214
Regioni1379 – 1381Acetyl-CoA bindingPROSITE-ProRule annotation3
Regioni1391 – 1392Acetyl-CoA bindingPROSITE-ProRule annotation2
Regioni1501 – 1559DisorderedSequence analysisAdd BLAST59
Regioni1819 – 1918DisorderedSequence analysisAdd BLAST100
Regioni2204 – 2241DisorderedSequence analysisAdd BLAST38
Regioni2249 – 2268DisorderedSequence analysisAdd BLAST20
Regioni2274 – 2326DisorderedSequence analysisAdd BLAST53
Regioni2338 – 2389DisorderedSequence analysisAdd BLAST52

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili1923 – 1954Sequence analysisAdd BLAST32

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi88 – 104Polar residuesSequence analysisAdd BLAST17
Compositional biasi118 – 147Polar residuesSequence analysisAdd BLAST30
Compositional biasi649 – 663Pro residuesSequence analysisAdd BLAST15
Compositional biasi824 – 845Polar residuesSequence analysisAdd BLAST22
Compositional biasi880 – 924Polar residuesSequence analysisAdd BLAST45
Compositional biasi934 – 998Basic and acidic residuesSequence analysisAdd BLAST65
Compositional biasi999 – 1015Polar residuesSequence analysisAdd BLAST17
Compositional biasi1501 – 1516Basic and acidic residuesSequence analysisAdd BLAST16
Compositional biasi1533 – 1547Basic residuesSequence analysisAdd BLAST15
Compositional biasi1824 – 1869Polar residuesSequence analysisAdd BLAST46
Compositional biasi1879 – 1910Pro residuesSequence analysisAdd BLAST32
Compositional biasi2204 – 2222Polar residuesSequence analysisAdd BLAST19
Compositional biasi2274 – 2314Polar residuesSequence analysisAdd BLAST41
Compositional biasi2342 – 2371Pro residuesSequence analysisAdd BLAST30

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri322 – 408TAZ-typePROSITE-ProRule annotationAdd BLAST87
Zinc fingeri1710 – 1791TAZ-typePROSITE-ProRule annotationAdd BLAST82

Keywords - Domaini

BromodomainPROSITE-ProRule annotationARBA annotation, Coiled coilSequence analysis, RepeatARBA annotation, Zinc-fingerPROSITE-ProRule annotationARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1778, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000155364

Database of Orthologous Groups

More...
OrthoDBi
236283at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
A0A0R4IVZ7

Family and domain databases

Conserved Domains Database

More...
CDDi
cd15802, RING_CBP-p300, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.246.20, 1 hit
1.20.1020.10, 2 hits
1.20.920.10, 1 hit
2.10.110.40, 1 hit
3.30.40.10, 1 hit
3.30.60.90, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001487, Bromodomain
IPR036427, Bromodomain-like_sf
IPR018359, Bromodomain_CS
IPR031162, CBP_P300_HAT
IPR013178, Histone_AcTrfase_Rtt109/CBP
IPR003101, KIX_dom
IPR036529, KIX_dom_sf
IPR009110, Nuc_rcpt_coact
IPR014744, Nuc_rcpt_coact_CREBbp
IPR010303, RING_CBP-p300
IPR038547, RING_CBP-p300_sf
IPR035898, TAZ_dom_sf
IPR013083, Znf_RING/FYVE/PHD
IPR000197, Znf_TAZ
IPR000433, Znf_ZZ
IPR043145, Znf_ZZ_sf

The PANTHER Classification System

More...
PANTHERi
PTHR13808, PTHR13808, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00439, Bromodomain, 1 hit
PF09030, Creb_binding, 1 hit
PF06001, DUF902, 1 hit
PF08214, HAT_KAT11, 1 hit
PF02172, KIX, 1 hit
PF02135, zf-TAZ, 2 hits
PF00569, ZZ, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00503, BROMODOMAIN

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00297, BROMO, 1 hit
SM01250, KAT11, 1 hit
SM00551, ZnF_TAZ, 2 hits
SM00291, ZnF_ZZ, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47040, SSF47040, 1 hit
SSF47370, SSF47370, 1 hit
SSF57933, SSF57933, 2 hits
SSF69125, SSF69125, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00633, BROMODOMAIN_1, 1 hit
PS50014, BROMODOMAIN_2, 1 hit
PS51727, CBP_P300_HAT, 1 hit
PS50952, KIX, 1 hit
PS50134, ZF_TAZ, 2 hits
PS01357, ZF_ZZ_1, 1 hit
PS50135, ZF_ZZ_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

A0A0R4IVZ7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MADNLLDMGP SAAKRPKLNS PALSSSDTPD FVSLFDLEND LPDELIPNGD
60 70 80 90 100
LGLMSMPSNG DGGVGSRMGG NVPDAAAKHK QLSQLLQAGS GSGLGGNLSP
110 120 130 140 150
QSGMGGQLGA LGKSPMGQGS PGHQTQAPKP VGTPTGQGNN SPGMGMNTGF
160 170 180 190 200
NPAMLNNNNQ AHGLMGQNMT PQGQMMNGVM GPAGRGRTAP GMQYQGQGMQ
210 220 230 240 250
GAPVGAGGGQ GVGVSGSVLA ETLTQGAPQM GAHNAINQQA GNMNKMGLAT
260 270 280 290 300
ANGPFGQQYV QGSVQQMSNA GLNAQMQNKA ALPNSLQPTL KGASSVPNLL
310 320 330 340 350
QQQVPSVGMV PGQGVSAGPT ADPEKRKLIQ QQLVLLLHAH KCQRREQANG
360 370 380 390 400
EVRACALPHC RTMKNVLNHM THCQAGKSCQ VAHCASSRQI ISHWKNCTRH
410 420 430 440 450
DCPVCLPLKN ASDKRNQQPM LSSPNPGMQS PLGQVGTSQP AAPAISSGTH
460 470 480 490 500
IDPSSMQRAY AALGLPYGNQ PAAQTQVAGQ QPTQTQQMRS MAALGSNQMN
510 520 530 540 550
IGGNGMADQT NLHTDSSLPS SLSSNQMMPD GSNMGGAGNL PTAAPLSMPG
560 570 580 590 600
MKKPWHEHVT QDLRNHLVHK LVQAIFPTPD PAALKDRRME NLVAYARKVE
610 620 630 640 650
GDMYESANSR DEYYHFLAEK IYKIQKELEE KRKSRLSKPQ MGAQGPQQPG
660 670 680 690 700
LPQPNPMGPA QAIRPPNGPV SMSNVPNQLM ARMQVPQGMG QFNPVTMQNV
710 720 730 740 750
QMSQSQVGAP RAASPMTHNP QMGMGNVPPM VMSPSRMPQA QAMMGGHANN
760 770 780 790 800
MVGQTPNQNQ FMNQTPFPAS AGGMNVNVNL AQQSGQTVQQ QQQQNANLTL
810 820 830 840 850
NAVGSLGPPS ALCSTPPPPS ASTPSAAASL QSLQTQPSTP ASVGGHVTPT
860 870 880 890 900
HIPSGLPRPP SVLGSSPAPS QPHTPLQSQP EPPMQMQQPT SVQAQQPSTP
910 920 930 940 950
LSQMAPSVDN RVPTPASVAE THSQQALPDY PAAEPKIEHQ EDEQEVESGK
960 970 980 990 1000
KRPDIKMEDE DVKPPQVKEQ PETVEPKQEP METEDKKPET KTEPKEEEVS
1010 1020 1030 1040 1050
STNSSTPANQ SAQSRKKIFK PEELRQALMP TLEALYRQDP ESLPFRQPVD
1060 1070 1080 1090 1100
PNLLGIPDYF DIVKNPIDLS TIKRKLDTGQ YQEPWQYVDD IWLMFNNAWL
1110 1120 1130 1140 1150
YNRKTSRVYK YCSKLAEVFE QEIDPVMQGL GYCCGRKYEF SPQTLCCYGK
1160 1170 1180 1190 1200
QLCTISRDGT YYSYQNRYHF CEKCFNEIQG DSVTLGDDPT QSQTYVSSAA
1210 1220 1230 1240 1250
QKSLSMISKE QFEKKKNDTL DSEPFVECKD CGRKMHQICV LHYDVIWPSG
1260 1270 1280 1290 1300
FICDNCLKKS GKSRKENKFS AKKLQCTRLG SYIEDRVNKY LKRQNHPEAG
1310 1320 1330 1340 1350
EVFVRVVASS DKTVEVKPGM KSRFVDSGEM SESFPYRTKA LFAFEEIDGV
1360 1370 1380 1390 1400
DVCFFGMHVQ EYGSDCPFPN TRRVYISYLD SIHFFKPRLL RTAVYHEILI
1410 1420 1430 1440 1450
GYLEYVKKLG YVTGHIWACP PSEGDDYIFH CHPPDQKIPK PKRLQEWYRK
1460 1470 1480 1490 1500
MLDKAFAERI IHDYKDIFKQ ATEDRLTSAY ELPYFEGDFW PNVLEESIKE
1510 1520 1530 1540 1550
LEQEEEERKK EENTASSETT EGAQADSKNA KKKNNKKTNK NKSSVSRANK
1560 1570 1580 1590 1600
KKPGMPNVAN DLSQKLYATM EKHKEVFFVI HLHAGPVVNT LPPIMDPDPL
1610 1620 1630 1640 1650
LTCDLMDGRD AFLTLARDKH WEFSSLRRCK WSTMCMLVEL HNQGQDRFVY
1660 1670 1680 1690 1700
TCNECKHHVE TRWHCTVCED FDLCINCYNS KGHEHQMVKW GLGLDDDSNN
1710 1720 1730 1740 1750
QGGEANKSPQ ESRRLSIQRC IQSLVHACQC RNANCSLPSC QKMKRVVQHT
1760 1770 1780 1790 1800
KGCKRKTNGG CPVCKQLIAL CCYHAKHCQE NKCPVPFCLN IKHKLRQQQI
1810 1820 1830 1840 1850
QQRLQQAQMM RRRMALMQGR GMPPSLPSPT TSGGPGTPNS QQLQQPNTPQ
1860 1870 1880 1890 1900
TSQALANQPQ QTHPNVAAMV QAFPNQPPTP GSQGKPGPQS SPLPQQQSPL
1910 1920 1930 1940 1950
PMPPQQQPQP SPQQQALKVA KQIEMMTKVK QQQQQQQQQQ QQQQQQQQQQ
1960 1970 1980 1990 2000
QQQDYRMSMN GMPMNQPRMM TSMQMMGPRG PQMVQNMQQG QWAPGMAMQN
2010 2020 2030 2040 2050
PQGPPPQQVP QQQMAMAQQQ SQVAQTPQQA QMIQRALMQQ QQQQQQQPRQ
2060 2070 2080 2090 2100
IQAVMPPQQV QPQAPQQQGM QQRGVTSNIT PGALQDLLRT LKSPSSPQQQ
2110 2120 2130 2140 2150
QQVLNILKSN PHLMAAFIKQ RTAKYQANQP QQQQNPQAML ASQQGMQNMA
2160 2170 2180 2190 2200
AMQPGSVQRP VMPPQQQPQP QPAATQAMAA LGSQGQMMNA AHNGNQQLFR
2210 2220 2230 2240 2250
RQLLRQMQQQ QQHQQQQGAM PPGQGRFPQP QGAASYSQIR VQQQMAMQGG
2260 2270 2280 2290 2300
AGPMGQMPPM AQMGQPGMGL DAQQQQNLMQ QRMLQQQQQQ QQQMMKQQMG
2310 2320 2330 2340 2350
SPAQAASMSP QPHMLGGQPQ GAHMPGQAMA NALGNQVRSP APVQSPRPPS
2360 2370 2380 2390 2400
QQPPHSSPSP RMQPQPSPLH PGSSHPSLAG PMPGPMDQAH MCTAEQSAML
2410 2420 2430
PQLNTPNRGG LTNDLNMDTT GDTLEKFVEG L
Length:2,431
Mass (Da):267,339
Last modified:June 20, 2018 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i39A00996A2D82997
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0R4IY90A0A0R4IY90_DANRE
Histone acetyltransferase
crebbpb
2,443Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BX957349 Genomic DNA No translation available.
CR339059 Genomic DNA No translation available.

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSDART00000168234.3; ENSDARP00000140135.2; ENSDARG00000112452.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX957349 Genomic DNA No translation available.
CR339059 Genomic DNA No translation available.

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000086306

Proteomic databases

PaxDbiA0A0R4IVZ7

Genome annotation databases

EnsembliENSDART00000168234.3; ENSDARP00000140135.2; ENSDARG00000112452.1

Organism-specific databases

ZFINiZDB-GENE-050302-102, crebbpb

Phylogenomic databases

eggNOGiKOG1778, Eukaryota
GeneTreeiENSGT00940000155364
OrthoDBi236283at2759
PhylomeDBiA0A0R4IVZ7

Family and domain databases

CDDicd15802, RING_CBP-p300, 1 hit
Gene3Di1.10.246.20, 1 hit
1.20.1020.10, 2 hits
1.20.920.10, 1 hit
2.10.110.40, 1 hit
3.30.40.10, 1 hit
3.30.60.90, 1 hit
InterProiView protein in InterPro
IPR001487, Bromodomain
IPR036427, Bromodomain-like_sf
IPR018359, Bromodomain_CS
IPR031162, CBP_P300_HAT
IPR013178, Histone_AcTrfase_Rtt109/CBP
IPR003101, KIX_dom
IPR036529, KIX_dom_sf
IPR009110, Nuc_rcpt_coact
IPR014744, Nuc_rcpt_coact_CREBbp
IPR010303, RING_CBP-p300
IPR038547, RING_CBP-p300_sf
IPR035898, TAZ_dom_sf
IPR013083, Znf_RING/FYVE/PHD
IPR000197, Znf_TAZ
IPR000433, Znf_ZZ
IPR043145, Znf_ZZ_sf
PANTHERiPTHR13808, PTHR13808, 1 hit
PfamiView protein in Pfam
PF00439, Bromodomain, 1 hit
PF09030, Creb_binding, 1 hit
PF06001, DUF902, 1 hit
PF08214, HAT_KAT11, 1 hit
PF02172, KIX, 1 hit
PF02135, zf-TAZ, 2 hits
PF00569, ZZ, 1 hit
PRINTSiPR00503, BROMODOMAIN
SMARTiView protein in SMART
SM00297, BROMO, 1 hit
SM01250, KAT11, 1 hit
SM00551, ZnF_TAZ, 2 hits
SM00291, ZnF_ZZ, 1 hit
SUPFAMiSSF47040, SSF47040, 1 hit
SSF47370, SSF47370, 1 hit
SSF57933, SSF57933, 2 hits
SSF69125, SSF69125, 1 hit
PROSITEiView protein in PROSITE
PS00633, BROMODOMAIN_1, 1 hit
PS50014, BROMODOMAIN_2, 1 hit
PS51727, CBP_P300_HAT, 1 hit
PS50952, KIX, 1 hit
PS50134, ZF_TAZ, 2 hits
PS01357, ZF_ZZ_1, 1 hit
PS50135, ZF_ZZ_2, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A0R4IVZ7_DANRE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A0R4IVZ7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: January 20, 2016
Last sequence update: June 20, 2018
Last modified: May 25, 2022
This is version 48 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again