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Protein

Microsomal triglyceride transfer protein large subunit

Gene

mttp

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Catalyzes the transport of triglyceride, cholesteryl ester, and phospholipid between phospholipid surfaces. Required for the secretion of plasma lipoproteins that contain apolipoprotein B.By similarity

<p>This subsection of the ‘Function’ section describes regulatory mechanisms for enzymes, transporters or microbial transcription factors, and reports the components which regulate (by activation or inhibition) the reaction.<p><a href='/help/activity_regulation' target='_top'>More...</a></p>Activity regulationi

Inhibited by naringenin.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • lipid binding Source: UniProtKB-KW
  • lipid transporter activity Source: ZFIN
  • phospholipid transporter activity Source: GO_Central

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processLipid transport, Transport
LigandLipid-binding

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-DRE-8866423 VLDL assembly
R-DRE-8963888 Chylomicron assembly

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Microsomal triglyceride transfer protein large subunit1 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:mttpCurated
Synonyms:mtpImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7955 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000437 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Zebrafish Information Network genome database

More...
ZFINi
ZDB-GENE-040419-2 mttp

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Endoplasmic reticulum

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the ‘Pathology and Biotech’ section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Larvae do not absorb dietary neutral lipids, consume very little yolk, are small and die by 6 days post-fertilization (dpf) with pronounced edema. No defects in intestinal absorption of short chain fatty acids. Loss of visualization of neutral lipids in the vasculature, heart and head structures by oil red o staining. Levels of apolipoprotein B, vitellogenin and lipovitellin unchanged. No cardiovascular defects or global intestinal function impairment. Increased expression of Foza2 and Pgc1 proteins (PubMed:17176039). Leads to excess angiogenesis and yolk absorption defects. Decreased mRNA levels of flt1 at 24 hours post-fertilization (hpf) with no change in the mRNA levels of kdrl or flt4 or in other vascular genes (PubMed:22581286).2 Publications

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 21Sequence analysisAdd BLAST21
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_500645176322 – 884Microsomal triglyceride transfer protein large subunitSequence analysisAdd BLAST863

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi172 ↔ 192PROSITE-ProRule annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi348N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Disulfide bondi438 ↔ 443PROSITE-ProRule annotation
Glycosylationi787N-linked (GlcNAc...) asparagine1

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
A0A0R4IVV0

PRoteomics IDEntifications database

More...
PRIDEi
A0A0R4IVV0

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Highest expression in the proximal part of the anterior intestine. Lower expression in the distal part of the anterior intestine, in the posterior portion of the intestinal tube and liver. Very low expression levels in heart, brain, ovary, testis and kidney.1 Publication

<p>This subsection of the ‘Expression’ section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified ‘at the protein level’.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Detected in the blastoderm margin by 4 hours post-fertilization (hpf). Expressed in the yolk syncytial layer (YSL) from 9 hpf to 24 hpf. By 48 hpf expression decreases in the extraembryonic YSL and is detected in the embryonic liver primordium and intestinal tube in which strongly expressed by 4 days post-fertilization (dpf). At 6 and 15 dpf expression is restricted to the two main liver lobes and the anterior part of the intestine including the intestinal bulb, but not detected in the pharynx or posterior intestine. Expressed in the enterocytes of the anterior part of intestine as well as in the hepatic cells in 15 dpf larvae. The total level of expression is very small before 2 hpf, increasing significantly between 2 and 5 hpf, and remaining high at 6 and 9 hpf. A significant decrease in the expression level is detected at 12 hpf and low level remains until the end of embryogenesis, which occurs by 72 hpf.1 Publication

<p>This subsection of the ‘Expression’ section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

Expression is strongly up-regulated in the anterior intestine and to a lesser extent in liver in response to feeding in both larvae and adults (at protein level) (PubMed:15614773). Protein levels are not changed in 1 or 6 hours after feeding (PubMed:17176039).2 Publications

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
A0A0R4IVV0 baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Heterodimer; heterodimerizes with the protein disulfide isomerase. Interacts with apolipoprotein B.By similarity

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
7955.ENSDARP00000024667

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
A0A0R4IVV0

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini26 – 660VitellogeninPROSITE-ProRule annotationAdd BLAST635

Keywords - Domaini

Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4337 Eukaryota
ENOG410YKCW LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000113688

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG006416

KEGG Orthology (KO)

More...
KOi
K14463

Identification of Orthologs from Complete Genome Data

More...
OMAi
EHWQSIR

Database of Orthologous Groups

More...
OrthoDBi
673565at2759

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.10.20, 1 hit
2.30.230.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR015819 Lipid_transp_b-sht_shell
IPR001747 Lipid_transpt_N
IPR011030 Lipovitellin_superhlx_dom
IPR039988 MTTP
IPR015816 Vitellinogen_b-sht_N

The PANTHER Classification System

More...
PANTHERi
PTHR13024 PTHR13024, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01347 Vitellogenin_N, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00638 LPD_N, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48431 SSF48431, 1 hit
SSF56968 SSF56968, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51211 VITELLOGENIN, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

A0A0R4IVV0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MMPVAGLLLC VTAVLCTSAL GAGPRLDNGK LYRYSYSTEV GLNRPTGSPG
60 70 80 90 100
GNVGFRISSD VDINLAWRNP EIQDEQLLQV KISNIQVESA GKHSRKNNIF
110 120 130 140 150
HGSSAESILG KVRLEALQRP FLVLWKMGKI RSLYAQKAEP ATVKNLKRGV
160 170 180 190 200
ASMLMMQLKS GKMSEADASG KCLVEYKVNK HQVIRTKHLE TCKSQETGFT
210 220 230 240 250
THSPVLGISG KCAAETVITL ENGIIKSADA KETHVLSINA RHKAATKVLS
260 270 280 290 300
RQSLTLKAIE AGPAEVAGKD VAGVVKALDD KFLSVGVIVE KTKPKCKGCP
310 320 330 340 350
NLMETWKAVR SQLEPNSLSK AEAPRSFLTL VHSLRKSSKS EILTVLQNCS
360 370 380 390 400
KTALPQLVDA VTSAQTPSSL SAILEFLDFS KKDGLILQER FLYACGFASH
410 420 430 440 450
PTESMLQSLL EVSQGKIGST EIKESVVIIM GALLRKLCLK GACDLPAVLK
460 470 480 490 500
VKELLLAGPD STQEESEVQM YLLALKNALL PEGIPVLAKY AESEVGAYST
510 520 530 540 550
IAITALQRYD PALITAEVKK ALNRIYHQNQ RIYEKNVRAA AADVIMSSNP
560 570 580 590 600
SYMEVKNLLL SIGHLPHEMN KYMLSKIQDV LRFQMPAYKL VRQVMKDMIS
610 620 630 640 650
HNYDRFSKTG SSSAYSGFMA ETVDVTCTYN LDILYSGSGV LRRSNMNIYG
660 670 680 690 700
QSNNALLHGL QVTIEAQGLE SLIAATPDEG EEELESFAGM SALLFDVQLR
710 720 730 740 750
PVTFFKGYSD LMSKMFSMSG DPINVVKGLI LLTDHSQVIP LQSGLRASAE
760 770 780 790 800
FQAGLSIDIS GGMEFSLWYR ESKTSVNNRG ALVIIGNMTV DTDFVSAGVE
810 820 830 840 850
VGFETEATLD FITTVQFSEY PFLVCMQMDK TTFPFRETVS KQEKLPTGQM
860 870 880
FSRKRSRDQV VPGSEFPLHQ ENSNMCKKVF EPAW
Length:884
Mass (Da):96,988
Last modified:January 20, 2016 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF152B03F919EA752
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q502S3Q502S3_DANRE
Microsomal triglyceride transfer pr...
mttp mtp
195Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F1QBU6F1QBU6_DANRE
Microsomal triglyceride transfer pr...
mttp mtp
155Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F1QGT1F1QGT1_DANRE
Microsomal triglyceride transfer pr...
mttp mtp
106Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti37S → G in CAD21747 (PubMed:15614773).Curated1
Sequence conflicti50G → E in CAD21747 (PubMed:15614773).Curated1
Sequence conflicti50G → E in AAI35021 (Ref. 3) Curated1
Sequence conflicti81K → Q in CAD21747 (PubMed:15614773).Curated1
Sequence conflicti81K → Q in AAI35021 (Ref. 3) Curated1
Sequence conflicti447A → V in CAD21747 (PubMed:15614773).Curated1
Sequence conflicti488A → T in CAD21747 (PubMed:15614773).Curated1
Sequence conflicti672L → P in CAD21747 (PubMed:15614773).Curated1
Sequence conflicti718M → T in CAD21747 (PubMed:15614773).Curated1
Sequence conflicti850M → T in AAI35021 (Ref. 3) Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AJ428850 mRNA Translation: CAD21747.1
BX908747 Genomic DNA No translation available.
CABZ01049941 Genomic DNA No translation available.
CABZ01050432 Genomic DNA No translation available.
CU914777 Genomic DNA No translation available.
FO704847 Genomic DNA No translation available.
BC135020 mRNA Translation: AAI35021.1

NCBI Reference Sequences

More...
RefSeqi
NP_998135.1, NM_212970.1

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Dr.105092
Dr.75507

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSDART00000015251; ENSDARP00000024667; ENSDARG00000008637

Database of genes from NCBI RefSeq genomes

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GeneIDi
406207

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dre:406207

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ428850 mRNA Translation: CAD21747.1
BX908747 Genomic DNA No translation available.
CABZ01049941 Genomic DNA No translation available.
CABZ01050432 Genomic DNA No translation available.
CU914777 Genomic DNA No translation available.
FO704847 Genomic DNA No translation available.
BC135020 mRNA Translation: AAI35021.1
RefSeqiNP_998135.1, NM_212970.1
UniGeneiDr.105092
Dr.75507

3D structure databases

SMRiA0A0R4IVV0
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000024667

Proteomic databases

PaxDbiA0A0R4IVV0
PRIDEiA0A0R4IVV0

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000015251; ENSDARP00000024667; ENSDARG00000008637
GeneIDi406207
KEGGidre:406207

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
4547
ZFINiZDB-GENE-040419-2 mttp

Phylogenomic databases

eggNOGiKOG4337 Eukaryota
ENOG410YKCW LUCA
HOGENOMiHOG000113688
HOVERGENiHBG006416
KOiK14463
OMAiEHWQSIR
OrthoDBi673565at2759

Enzyme and pathway databases

ReactomeiR-DRE-8866423 VLDL assembly
R-DRE-8963888 Chylomicron assembly

Miscellaneous databases

Protein Ontology

More...
PROi
PR:A0A0R4IVV0

Gene expression databases

ExpressionAtlasiA0A0R4IVV0 baseline and differential

Family and domain databases

Gene3Di1.25.10.20, 1 hit
2.30.230.10, 1 hit
InterProiView protein in InterPro
IPR015819 Lipid_transp_b-sht_shell
IPR001747 Lipid_transpt_N
IPR011030 Lipovitellin_superhlx_dom
IPR039988 MTTP
IPR015816 Vitellinogen_b-sht_N
PANTHERiPTHR13024 PTHR13024, 1 hit
PfamiView protein in Pfam
PF01347 Vitellogenin_N, 1 hit
SMARTiView protein in SMART
SM00638 LPD_N, 1 hit
SUPFAMiSSF48431 SSF48431, 1 hit
SSF56968 SSF56968, 1 hit
PROSITEiView protein in PROSITE
PS51211 VITELLOGENIN, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMTP_DANRE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A0R4IVV0
Secondary accession number(s): A4IGB9, Q8AXV7
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 15, 2017
Last sequence update: January 20, 2016
Last modified: January 16, 2019
This is version 23 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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