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Entry version 19 (08 May 2019)
Sequence version 1 (20 Jan 2016)
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Protein
Submitted name:

Mucin 5.3

Gene

muc5.3

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-DRE-913709 O-linked glycosylation of mucins
R-DRE-977068 Termination of O-glycan biosynthesis

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Mucin 5.3Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:muc5.3Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7955 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000437 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Zebrafish Information Network genome database

More...
ZFINi
ZDB-GENE-040426-1562 muc5.3

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 35Sequence analysisAdd BLAST35
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_500645094636 – 5692Sequence analysisAdd BLAST5657

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi5606 ↔ 5655PROSITE-ProRule annotation
Disulfide bondi5617 ↔ 5671PROSITE-ProRule annotation
Disulfide bondi5621 ↔ 5673PROSITE-ProRule annotation

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationSAAS annotation

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
A0A0R4I9R7

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
7955.ENSDARP00000124449

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini64 – 264VWFDInterPro annotationAdd BLAST201
Domaini416 – 631VWFDInterPro annotationAdd BLAST216
Domaini885 – 1088VWFDInterPro annotationAdd BLAST204
Domaini5339 – 5407VWFCInterPro annotationAdd BLAST69
Domaini5445 – 5514VWFCInterPro annotationAdd BLAST70
Domaini5586 – 5679CTCKInterPro annotationAdd BLAST94

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000162219

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR006207 Cys_knot_C
IPR036084 Ser_inhib-like_sf
IPR002919 TIL_dom
IPR014853 Unchr_dom_Cys-rich
IPR001007 VWF_dom
IPR001846 VWF_type-D

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF08742 C8, 3 hits
PF01826 TIL, 1 hit
PF00094 VWD, 3 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00832 C8, 3 hits
SM00041 CT, 1 hit
SM00214 VWC, 4 hits
SM00215 VWC_out, 2 hits
SM00216 VWD, 3 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF57567 SSF57567, 4 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS01185 CTCK_1, 1 hit
PS01225 CTCK_2, 1 hit
PS01208 VWFC_1, 1 hit
PS50184 VWFC_2, 2 hits
PS51233 VWFD, 3 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Fragment.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

A0A0R4I9R7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
XRWRASSSAS AMGSINIMSI AALIWITLTA GPAAAQTVFT TMNLIPTATI
60 70 80 90 100
EMVAGLTSQH NELICSTWGN YHYKTFDGDY FQLPSTCNYI LTSHCSSSYE
110 120 130 140 150
DFNVQLRHEL LNNEPTVSKI TMKLQGTIIE LSRDSLSVNG QTVTLPYSSA
160 170 180 190 200
EVFIERVTSY ISIKAALGLV AMWNEDDSFM IRLDEKYRNQ TCGLCGDFNG
210 220 230 240 250
IPVYNEFVSG GSSLSVSDYG NLWKLDGPTE TCTEDTMFLN ENCGDENFCR
260 270 280 290 300
DIFSSPVFSD CRGLVSIDSF VQVCIQDLCH CNSSSGAFCL CDTIAEYSRQ
310 320 330 340 350
CVHAGGKPEE WRTEYFCPHP CPETMVYSQC GNPCTDTCTN SERGQVCAQH
360 370 380 390 400
CIDGCFCPPG TVYDDIHQSG CIPYTECSCV LGGKIYASGE NYTSNCRDCT
410 420 430 440 450
CDQGQWDCYI KDCPHSCSVE GGSHITTFDG KAYTFHGDCT YVLSKHCSGT
460 470 480 490 500
EFTVLGDLVK CGLTETETCL KAITVALFDG ITVINVDSSG NVEVNRIVAQ
510 520 530 540 550
LPLFTSSVSV FKPSSFYIII EAPLIGLRLE IQLVPIMQLY ITANSVYQGE
560 570 580 590 600
TCGLCGNYNN MEADDFTTIG GLREGTALDF ANTWKTRASC PDVKRSFENP
610 620 630 640 650
CSLSTENEQY AQHWCSLLSD SSSVFAPCHT EVNPEVYKAN CIYDSCNCER
660 670 680 690 700
SEDCMCAALS SYAHACAARG ILLEGWRDAA CMKYTETCAA TTVYSYQMTS
710 720 730 740 750
CGRTCRSLSQ ADGSCTHDHV LVDGCGCAEG KYMNENGDCV EAAACSCYDS
760 770 780 790 800
GKVVALGETI SKDGGSCICQ QGKLSCSGVS NGEECTEPMR FFNCSSASPG
810 820 830 840 850
SEGAECQKSC NTLDMACIST GCVSGCVCPS GLVSDGNGGC IDKDQCPCIH
860 870 880 890 900
NGHTYQSGES IKIDCNTCSC QNRRWTCTTN QCSATCSIYG DGHYRTFDDK
910 920 930 940 950
RYVFSGNCEY SLVQDFCNST SGTFRVITEN IPCGSTGTTC SKAIKLFLGS
960 970 980 990 1000
NELRLTDGSF QVVRRDAGEE IPYQMRTMGL YLVIETKNGL MLIWDRKTTI
1010 1020 1030 1040 1050
HIKLGPEYNG RVCGLCGNYD GNANNDFTTR TQAVAVQALD FANSWKLSSC
1060 1070 1080 1090 1100
PDATLIQDPC AHNPYREAWA QRQCSIITSS VFSACHSQVD PSPFYDACVR
1110 1120 1130 1140 1150
DACACDSGGD YECFCTAVTA YAQACNEAGA CVAWRSPKIC PLFCDYYNPP
1160 1170 1180 1190 1200
GECEWHYKPC GAPCMKTCRN PDEQCSNQIP ALEGCYPQCP QEQPVFDEDN
1210 1220 1230 1240 1250
MKCVKQEECG CFVDMEHYEV GEQVPTTENC QSCNCSSTGV ICEFDINACR
1260 1270 1280 1290 1300
CQYNNDTYYY GDIIYHTTDG LGGCITGICS VNGTIERSID PCETTTVPTT
1310 1320 1330 1340 1350
TSSLITTPTP TTVFVFSTPE STTSEVSYTT KKPEQLTTGT TAEVIQTAST
1360 1370 1380 1390 1400
REIKHSTEQQ VYVTTKPSTS LPTTMKKTSE SETSTNILTT TMETSIAPIT
1410 1420 1430 1440 1450
KTLPTVTDKP WTTLSTQSQS VSTRQTTEEQ TTENELTTLE TTLSTTRPPK
1460 1470 1480 1490 1500
VVTTGQTIQP TTTATTTVEE LTATSPESST PSSTSVPLRQ TSPAITSTQP
1510 1520 1530 1540 1550
TTLTKTTAVP VTTLVSTTVT VESSTELEVS TQSPSSTTKP IKAETTLSTT
1560 1570 1580 1590 1600
TAETPSTTVL VEGSSTVQQP TETSAPSILS TTSKSSTSTE TTGVVTTTET
1610 1620 1630 1640 1650
VTENELSTSE TTMSTTRPPK VVTTGQTIQP TTTATTTVEE LTATSPESST
1660 1670 1680 1690 1700
PSSTSVPLRK TSPAITSSQP TTLTKTTAVP VTTLVSTTVS VESSTEFEVS
1710 1720 1730 1740 1750
TQGPSSTTKP IKAETTLSTT TAETPSTTVL VEGSSTVQHP TETSAPSILS
1760 1770 1780 1790 1800
TTSKSSTSTE TTGVVTTTET VTENELSTSE TTLSTTRPPK VVTTGQTIQP
1810 1820 1830 1840 1850
TTTATTTVEE LTATSPESST PSSTSVPLRQ TSPAITSTQP TTLTKTTAVP
1860 1870 1880 1890 1900
VTTLVSTTVS VESSTEFEVS TQSPSSTTKP IKAETTLSTT TAAIPSTTFS
1910 1920 1930 1940 1950
VVEGSTTVQP SAPSILSTTS KSSTATETTG VVTTTETVTE NELSTSEKTL
1960 1970 1980 1990 2000
STTRPPKVVT TGQTIQPTTT ATTTVEELTA TSPESSTPSS TSVPLRQTSP
2010 2020 2030 2040 2050
PITSTQPTTV TKTTAVPVTT LVSTTVSVES STKFEVSTQG PSSTTKPIKA
2060 2070 2080 2090 2100
ETTLSTTTAE TPSTTVLVEG SSTVQQPTET SAPSILSTTS KSSTVTETTG
2110 2120 2130 2140 2150
VVTTTETVTE NELSTSETTL STTRPPKVVT TGQTIQPTTT ATTTVEELTA
2160 2170 2180 2190 2200
TSPESSTPSS TSVPLRQTSP AITSTQPTTV TKTTAVPVTT LVSTTVTVES
2210 2220 2230 2240 2250
STELEVSTQG PSSTTKPIKA ETTLSTTTAE TPSTTVLVEG SSTVQQPTET
2260 2270 2280 2290 2300
SAPSILSTTS KSSTSTETTG VVTTTETVTE NELSTSETTL STTRPPKVVT
2310 2320 2330 2340 2350
TGQTIQPTTT ATTTVEELTA TSPESSTPSS TSVPLRQTSP AITSTQPTTV
2360 2370 2380 2390 2400
TKTTAVPVTT LVSTTVSVES STEFEVSTQG PSSTTKPIKA ETTLSTTTAE
2410 2420 2430 2440 2450
TPSTTVLVEG SSTVQQPTET SAPSILSTTS KSSTVTETTG VVTSTETVTE
2460 2470 2480 2490 2500
NELSTSETTL STTRPPKVVT TGQTIEPTTT ATTTVEELTP TSPESSTPSS
2510 2520 2530 2540 2550
TLVPVRQTSP AITSTQPTTL TKTTAVPVTT LVSTTVTVES STEFEVSTQS
2560 2570 2580 2590 2600
PSSTTKPIKA ETTLSTTTAE TPSTTVLVEG SSTVQQPTET SAPSILSTTS
2610 2620 2630 2640 2650
KSSTVTETTG VVTTTETVTE NELSTSETTL STTRPPKVVT TGQTIQPTTT
2660 2670 2680 2690 2700
ATTTVEELTA TSPESSTPSS TSVPLRQTSP AITSTQPTTL TKTTAVPVTT
2710 2720 2730 2740 2750
LVSTTVSVES STEFEVSTQG PSSTTKPIKA ETTLSTTTAA IPSTTFSVVE
2760 2770 2780 2790 2800
GSTTVQPSAP SILSTTSKSS TVTETTGVVT TTETVTENEL STSETTLSTT
2810 2820 2830 2840 2850
RPPKVVTTGQ TIQPTTTATT TVEELTATSP ESSTPSSTSL PVRQTSPAIT
2860 2870 2880 2890 2900
STQPTTVTKT TAVPVTTLVS TTVTVESSTE FEVSTQGPSS TTKPIKAETT
2910 2920 2930 2940 2950
LSTTTAETPS TTVLVEGSST VQHPTETSAP SILSTTSKSS TSTETTGVVT
2960 2970 2980 2990 3000
TTETVTENEL STSETTMSTT RPPKVVTTGQ TIQPTTTATT TVEELTATSP
3010 3020 3030 3040 3050
ESSTPSSTSV PLRQTSPAIT STQPTTVTKT TAVPVTTLVS TTVSVESSTE
3060 3070 3080 3090 3100
FEVSTQSPSS TTKPIKAETT LSTTTAETPS TTVLVEGSST VQQPTETSAP
3110 3120 3130 3140 3150
SILSTTSKSS TVTETTGVVT TTETVTENEL STSETTLSTT RPPQVVTTGQ
3160 3170 3180 3190 3200
TIQPTTTATT TVEELTATSP ESSTPSSTSV PLRQTSPAIT STQPTTVTKT
3210 3220 3230 3240 3250
TAVPVTTLVS TTVTVESSTE LEVSTQSPSS TTKPIKAETT LSTTTAETPS
3260 3270 3280 3290 3300
TTVLVEGSST VQHPTETSAP SILSTTSKSS TSTETTGVVT TTETVTENEL
3310 3320 3330 3340 3350
STSETTMSTT RPPKVVTTGQ TIQPTTTATT TVEELTATSP ESSTPSSTSV
3360 3370 3380 3390 3400
PLRQTSPAIT STQPTTLTKT TAVPVTTLVS TTVSVESSTE FEVSTQGPSS
3410 3420 3430 3440 3450
TTKPIKAETT LSTTTAAIPS TTFSVVEGST TVQPSAPSIL STTSKSSTVT
3460 3470 3480 3490 3500
ETTGVVTTTE TVTENELSTS ETTLSTSRPP KVVTTGQTIQ PTTTATTTVE
3510 3520 3530 3540 3550
ELMATSPESS TPSSTSLPVR QTSPAITSTQ PTTLTKTTAV PVTTLVSTTV
3560 3570 3580 3590 3600
TVESSTEFEV STQGPSSTTK PIKAETTLST TTAETPSTTV LVEGSSTVQH
3610 3620 3630 3640 3650
PTETSAPSIL STTSKSSTST ETTGVVTTTE TVTENELSTS ETTMSTTRPP
3660 3670 3680 3690 3700
KVVTTGQTIQ PTTTATTTVE ELTATSPESS TPSSTSVPLK QTSPTITSTQ
3710 3720 3730 3740 3750
PTTVTKTTAV PVTTLVSTTV SVESSTEFEV STQSPSSTTK PIKAETTLST
3760 3770 3780 3790 3800
TTAETPSTTV LLEGSSTVQQ PTDTSAPSIL STTSKSSTVT ETTGVVTTTE
3810 3820 3830 3840 3850
TVTENELSTS ETTLSTTRPP KVVTTSQTIQ PTTTATTTVE ELTATSPESS
3860 3870 3880 3890 3900
TPSSTSVPLR QTSPAITSTQ PTTLTKTTAV PVTTLVSTTV SVESSTEFEV
3910 3920 3930 3940 3950
STQSPSSTTK PIKAETTLST TTAETPSTTV LVEGSSTVQK PTETSAPSIL
3960 3970 3980 3990 4000
STTSKSSTVT ETTGVVTTTE TVTENELSTS ETTLSTSRPP KVVTTGQTIQ
4010 4020 4030 4040 4050
PTTTATTTVE ELTATSPESS TPSSTSLPVR QTSPAITSTQ PTTVTKTTAV
4060 4070 4080 4090 4100
PVTTLVSTTV TVESSTEFEV STQGPSSTTK PIKAETTLST TTAETPSTTV
4110 4120 4130 4140 4150
LVEGSSTVQH PTETSAPSIL STTSKSSTST ETTGVVTTTE TVTENELSTS
4160 4170 4180 4190 4200
ETTLSTTRPP KVVTTGQTIQ PTTTATTTVG ELTATSPESS TPSSTSVPLR
4210 4220 4230 4240 4250
QTSPAITSTQ PTTLTKTTAV PVTTLVSTTV SVESSTEFEV STQSPSSTTK
4260 4270 4280 4290 4300
PIKAETTLST TTAETPSTTV LVEGSSTVQQ PTETSAPSIL STTSKSSTVT
4310 4320 4330 4340 4350
ETIGVVTTTE TVTENELSTS ETTLSTTRPP KVVTTGQTIQ PTTTATTTVE
4360 4370 4380 4390 4400
ELTATSPESS TPSSTSVPLR QTSPAITSTQ PTTLTKTTAV PVTTLVSTTV
4410 4420 4430 4440 4450
SVESSTEFEV STQGPSSTTK PIKAETTLST TTAAIPSTTF SVVEGSTTVQ
4460 4470 4480 4490 4500
PSAPSILSTT SKSSTVTETT GVVTTTETVT ENELSTSETT LSTTRPPKVV
4510 4520 4530 4540 4550
TTGQTIQPTT TATTTVEELT ATSPESSTPS STSLPVRQTS PAITSTQPTT
4560 4570 4580 4590 4600
VTKTTAVPVT TLVSTTVTVE SSTEFEVSTQ GPSSTTKPIK AETTLSTTTA
4610 4620 4630 4640 4650
ETPSTTVLVE GSSTVQHPTE TSAPSILSTT SKSSTSTETT GVVTTTETVT
4660 4670 4680 4690 4700
ENELSTSETT LSTTRPPKVV TTGQTIQPTT TATTTVEELT ATSPESSTPS
4710 4720 4730 4740 4750
STSVPLRQTS PAITSTQPTT LTKTTAVPVT TLVSTTVTVE SSTEFEVSTQ
4760 4770 4780 4790 4800
GPSSTTKPIK AETTLSTTTA AIPSTTFSVV EGSTTVQPSA PSILSTTSKS
4810 4820 4830 4840 4850
STATETTGVV TTTETVTENE LSTSETTLST TRPPKVVTTG QTIQPTTTAT
4860 4870 4880 4890 4900
TTVEELTATS PDSSTPSSTS LPVRQTSPAI TSTQPTTVTK TTAVPVTTLV
4910 4920 4930 4940 4950
STTVTVESST EFEVSTQGPS STTKPIKAET TLSTTTAETP STTVLVEGSS
4960 4970 4980 4990 5000
TVQQPTETSA PSILSTTSKS STVTETTGVV TTTETVTENE LSTSETTLST
5010 5020 5030 5040 5050
TRPPKVVTTG QTIQPTTTAT TTVEELTATS PESSTPSSTS VPLRQTSPAI
5060 5070 5080 5090 5100
TSTQPTTLTK TTAVPVTTLV STTVSVESST EFEVSTQGPS STTKPIKAET
5110 5120 5130 5140 5150
TLSTTTAAIP STTFSVVEGS TTVQPSAPSI LSTTSKSSTV TETTGVVTTT
5160 5170 5180 5190 5200
ETVTENELST SETTLSTTRP PKVVTTGQTI QPTTTATTTS EEGTTLETTK
5210 5220 5230 5240 5250
STISPVVTTN VFYFSTSMET SIAPITKTLP FFTLTIPVTT DSSLFSTTSE
5260 5270 5280 5290 5300
FCCFVNETNF HSGDIIYNVT DGFGWCFTAY CDESCNIVKI STSCVTSPSP
5310 5320 5330 5340 5350
SIPPETTTYS SSSTAGTNEP ETIISTTNTI TEETTPSLPR CDAIDPPRQP
5360 5370 5380 5390 5400
NEAWWSECQK CECDSQTLTV ICRPVNCPVS PPITCDKPGQ MLITVATVDC
5410 5420 5430 5440 5450
CEIQDCTCNS SLCPTPPQQC QPGFTLTPVI TADACCPEYT CSPMEVCVQN
5460 5470 5480 5490 5500
NTVYQPGSNI PSDDPCTQCL CGQDTDPETN LLAPECHSLA CMMYCPEETH
5510 5520 5530 5540 5550
EYRKLPGQCC GECVSTECVV VHDNITVNIP VNQTWQPDDK CLTYRCERNN
5560 5570 5580 5590 5600
GVSMPVEIKT VCPAFNPEDC IPGTETLDAD GCCPTCTLEN KCTVQKNSTF
5610 5620 5630 5640 5650
LVSKGCKSST PVEITSCSGL CGTSSIYSAE ANALVHSCSC CQETTTSTKE
5660 5670 5680 5690
VTLNCPDGSN ISFSYIYIES CGCKASNCPD QSTNMRRRRR RK
Length:5,692
Mass (Da):595,088
Last modified:January 20, 2016 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA5620B7A99B7F724
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A2R8QBQ7A0A2R8QBQ7_DANRE
Mucin 5.3
muc5.3
96Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section is used for sequence fragments to indicate that the residue at the extremity of the sequence is not the actual terminal residue in the complete protein sequence.<p><a href='/help/non_ter' target='_top'>More...</a></p>Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
CU463038 Genomic DNA No translation available.
CU463947 Genomic DNA No translation available.

Genome annotation databases

Ensembl eukaryotic genome annotation project

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Ensembli
ENSDART00000162367; ENSDARP00000130459; ENSDARG00000099470

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU463038 Genomic DNA No translation available.
CU463947 Genomic DNA No translation available.

3D structure databases

Database of comparative protein structure models

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ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000124449

Proteomic databases

PaxDbiA0A0R4I9R7

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000162367; ENSDARP00000130459; ENSDARG00000099470

Organism-specific databases

ZFINiZDB-GENE-040426-1562 muc5.3

Phylogenomic databases

GeneTreeiENSGT00940000162219

Enzyme and pathway databases

ReactomeiR-DRE-913709 O-linked glycosylation of mucins
R-DRE-977068 Termination of O-glycan biosynthesis

Family and domain databases

InterProiView protein in InterPro
IPR006207 Cys_knot_C
IPR036084 Ser_inhib-like_sf
IPR002919 TIL_dom
IPR014853 Unchr_dom_Cys-rich
IPR001007 VWF_dom
IPR001846 VWF_type-D
PfamiView protein in Pfam
PF08742 C8, 3 hits
PF01826 TIL, 1 hit
PF00094 VWD, 3 hits
SMARTiView protein in SMART
SM00832 C8, 3 hits
SM00041 CT, 1 hit
SM00214 VWC, 4 hits
SM00215 VWC_out, 2 hits
SM00216 VWD, 3 hits
SUPFAMiSSF57567 SSF57567, 4 hits
PROSITEiView protein in PROSITE
PS01185 CTCK_1, 1 hit
PS01225 CTCK_2, 1 hit
PS01208 VWFC_1, 1 hit
PS50184 VWFC_2, 2 hits
PS51233 VWFD, 3 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A0R4I9R7_DANRE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A0R4I9R7
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: January 20, 2016
Last sequence update: January 20, 2016
Last modified: May 8, 2019
This is version 19 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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