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Protein

Ribonuclease 3

Gene

rnc

Organism
Lactobacillus xiangfangensis
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.UniRule annotation

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

Endonucleolytic cleavage to 5'-phosphomonoester.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi48MagnesiumUniRule annotation1
Active sitei52UniRule annotation1
Metal bindingi121MagnesiumUniRule annotation1
Active sitei124UniRule annotation1
Metal bindingi124MagnesiumUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionEndonucleaseUniRule annotationSAAS annotation, Hydrolase, Nuclease, RNA-binding, rRNA-bindingUniRule annotationSAAS annotation
Biological processmRNA processingUniRule annotationSAAS annotation, rRNA processingUniRule annotationSAAS annotation, tRNA processingUniRule annotationSAAS annotation
LigandMagnesiumUniRule annotationSAAS annotation, Metal-bindingUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease 3UniRule annotation (EC:3.1.26.3UniRule annotation)
Alternative name(s):
Ribonuclease IIIUniRule annotation
Short name:
RNase IIIUniRule annotation
Gene namesi
Name:rncUniRule annotation
ORF Names:IV64_GL000538Imported
OrganismiLactobacillus xiangfangensisImported
Taxonomic identifieri942150 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus
Proteomesi
  • UP000051783 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Homodimer.UniRule annotationSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini6 – 135RNase IIIInterPro annotationAdd BLAST130
Domaini161 – 230DRBMInterPro annotationAdd BLAST70

Sequence similaritiesi

Belongs to the ribonuclease III family.SAAS annotation

Family and domain databases

CDDicd00593 RIBOc, 1 hit
Gene3Di1.10.1520.10, 1 hit
HAMAPiMF_00104 RNase_III, 1 hit
InterProiView protein in InterPro
IPR014720 dsRBD_dom
IPR011907 RNase_III
IPR000999 RNase_III_dom
IPR036389 RNase_III_sf
PfamiView protein in Pfam
PF00035 dsrm, 1 hit
PF14622 Ribonucleas_3_3, 1 hit
SMARTiView protein in SMART
SM00358 DSRM, 1 hit
SM00535 RIBOc, 1 hit
SUPFAMiSSF69065 SSF69065, 1 hit
TIGRFAMsiTIGR02191 RNaseIII, 1 hit
PROSITEiView protein in PROSITE
PS50137 DS_RBD, 1 hit
PS50142 RNASE_3_2, 1 hit

Sequencei

Sequence statusi: Complete.

A0A0R2M976-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MITELAAMLK DRFGIVFNNP DLLAEAFTQA SYVNEHQDQN LKFYERVEFL
60 70 80 90 100
GDAVLELAVS EYLYKRYKDM PQGKLTRLRA AMVCEDSFAS FARECGFPQY
110 120 130 140 150
IRLGKGEQKA RAWERDSLLC DIFESFVGAL YLDQGREPVL KFVRQVIFPK
160 170 180 190 200
LDEGRFDGVF DYKTTLQEYL QRDGDVAIDY QLIEQDGPAN ERSYEIAVLA
210 220 230
DGKKIGQGWG HSKKEAEQSA AHQAYTQAQQ QD
Length:232
Mass (Da):26,612
Last modified:January 20, 2016 - v1
Checksum:iCD98632F4545CECD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JQCL01000080 Genomic DNA Translation: KRO08450.1
RefSeqiWP_057707044.1, NZ_JQCL01000080.1

Genome annotation databases

EnsemblBacteriaiKRO08450; KRO08450; IV64_GL000538
PATRICifig|942150.3.peg.551

Similar proteinsi

Entry informationi

Entry nameiA0A0R2M976_9LACO
AccessioniPrimary (citable) accession number: A0A0R2M976
Entry historyiIntegrated into UniProtKB/TrEMBL: January 20, 2016
Last sequence update: January 20, 2016
Last modified: March 28, 2018
This is version 18 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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