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Protein

V-type proton ATPase subunit a

Gene

Dmoj\GI22777

Organism
Drosophila mojavensis (Fruit fly)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processHydrogen ion transportUniRule annotation, Ion transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
V-type proton ATPase subunit aUniRule annotation
Gene namesi
Name:Dmoj\GI22777Imported
ORF Names:Dmoj_GI22777Imported, GI22777Imported
OrganismiDrosophila mojavensis (Fruit fly)Imported
Taxonomic identifieri7230 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophila
Proteomesi
  • UP000009192 Componenti: Unassembled WGS sequence

Organism-specific databases

FlyBaseiFBgn0145504 Dmoj\GI22777

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei421 – 449HelicalUniRule annotationAdd BLAST29
Transmembranei469 – 489HelicalUniRule annotationAdd BLAST21
Transmembranei559 – 577HelicalUniRule annotationAdd BLAST19
Transmembranei592 – 612HelicalUniRule annotationAdd BLAST21
Transmembranei624 – 643HelicalUniRule annotationAdd BLAST20
Transmembranei663 – 682HelicalUniRule annotationAdd BLAST20
Transmembranei757 – 779HelicalUniRule annotationAdd BLAST23
Transmembranei785 – 809HelicalUniRule annotationAdd BLAST25

Keywords - Cellular componenti

Membrane

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili51 – 71Sequence analysisAdd BLAST21
Coiled coili94 – 128Sequence analysisAdd BLAST35

Sequence similaritiesi

Belongs to the V-ATPase 116 kDa subunit family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixUniRule annotation

Family and domain databases

InterProiView protein in InterPro
IPR002490 V-ATPase_116kDa_su
IPR026028 V-type_ATPase_116kDa_su_euka
PANTHERiPTHR11629 PTHR11629, 1 hit
PfamiView protein in Pfam
PF01496 V_ATPase_I, 1 hit
PIRSFiPIRSF001293 ATP6V0A1, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 8 potential isoforms that are computationally mapped.Show allAlign All

A0A0Q9X8P4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGSLFRSEEM ALCQLFLQSE AAYACVSELG ELGLVQFRDL NPDVNAFQRK
60 70 80 90 100
FVNEVRRCDE MERKLRYLEK EIKKDGIPML DTGESPEAPQ PREMIDLEAT
110 120 130 140 150
FEKLENELRE VNQNAEALKR NFLELTELKH ILRKTQVFFD ESVPMVYKST
160 170 180 190 200
STYSSNKYRR YLQMADNQNE DEQAQLLGEE GVRANQPGQN LKLGFVAGVI
210 220 230 240 250
SREKLPAFER MLWRACRGNV FLRQAMIESP LEDPTNGDQV YKSVFIIFFQ
260 270 280 290 300
GDQLKTRVKK ICEGFRATLY PCPEAPADRR EMAMGVMTRI EDLNTVLGQT
310 320 330 340 350
QDHRHRVLVA AAKNLKNWFV KVRKIKAIYH TLNLFNLDVT QKCLIAECWV
360 370 380 390 400
PLLDIETIQL ALRRGTERSG SSVPPILNRM QTFENPPTYN RTNKFTKAFQ
410 420 430 440 450
ALIDAYGVAS YREMNPAPYT IITFPFLFAV MFGDLGHGAI MALFGLWMIR
460 470 480 490 500
KEKGLAAQKT DNEIWNIFFG GRYIIFLMGV FSMYTGLIYN DIFSKSLNIF
510 520 530 540 550
GSHWHLSYNK STVWNNNYLQ LSPATSDYEG TPYPFGMDPI WQVASSNKIV
560 570 580 590 600
FQNAYKMKIS IIFGVLHMIF GVIMSWHNHT YFRNRLSLLY EFIPQLLFLV
610 620 630 640 650
VLFFYLVLLM FIKWNRYAAT NAFPMTEACA PSILITFIDM VLFKNSKAPG
660 670 680 690 700
KDCNIYMFAG QSFFQTIFVL IALACIPVML LGKPIKIMQA RKLANVQPIT
710 720 730 740 750
GASDAEVGGM SNGGGSHGGG GEHHDEEEMS EIFIHQGIHT IEYVLGSVSH
760 770 780 790 800
TASYLRLWAL SLAHAQLAEV LWSMVLSLGL NKEGWLGGIF LTVVFAFWAV
810 820 830 840 850
LTVGILVLME GLSAFLHTLR LHWVEFQSKF YMGHGYAFQP FSFDTIIENG

GAVTETE
Length:857
Mass (Da):97,720
Last modified:January 20, 2016 - v1
Checksum:i8C970099382EF3D8
GO

Computationally mapped potential isoform sequencesi

There are 8 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0Q9X9R1A0A0Q9X9R1_DROMO
V-type proton ATPase subunit a
Dmoj\GI22777 Dmoj_GI22777, GI22777
859Annotation score:
B4K8N3B4K8N3_DROMO
V-type proton ATPase subunit a
Dmoj\GI22777 Dmoj_GI22777, GI22777
854Annotation score:
A0A0Q9X0Y9A0A0Q9X0Y9_DROMO
V-type proton ATPase subunit a
Dmoj\GI22777 Dmoj_GI22777, GI22777
837Annotation score:
A0A0Q9X0A1A0A0Q9X0A1_DROMO
V-type proton ATPase subunit a
Dmoj\GI22777 Dmoj_GI22777, GI22777
853Annotation score:
A0A0Q9XAZ7A0A0Q9XAZ7_DROMO
V-type proton ATPase subunit a
Dmoj\GI22777 Dmoj_GI22777, GI22777
852Annotation score:
A0A0Q9XCS9A0A0Q9XCS9_DROMO
V-type proton ATPase subunit a
Dmoj\GI22777 Dmoj_GI22777, GI22777
835Annotation score:
A0A0Q9X0A0A0A0Q9X0A0_DROMO
V-type proton ATPase subunit a
Dmoj\GI22777 Dmoj_GI22777, GI22777
838Annotation score:
A0A0Q9X256A0A0Q9X256_DROMO
V-type proton ATPase subunit a
Dmoj\GI22777 Dmoj_GI22777, GI22777
840Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH933806 Genomic DNA Translation: KRG01556.1
RefSeqiXP_015022662.1, XM_015167176.1

Genome annotation databases

EnsemblMetazoaiFBtr0429738; FBpp0387171; FBgn0145504
GeneIDi6573932

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH933806 Genomic DNA Translation: KRG01556.1
RefSeqiXP_015022662.1, XM_015167176.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0429738; FBpp0387171; FBgn0145504
GeneIDi6573932

Organism-specific databases

FlyBaseiFBgn0145504 Dmoj\GI22777

Family and domain databases

InterProiView protein in InterPro
IPR002490 V-ATPase_116kDa_su
IPR026028 V-type_ATPase_116kDa_su_euka
PANTHERiPTHR11629 PTHR11629, 1 hit
PfamiView protein in Pfam
PF01496 V_ATPase_I, 1 hit
PIRSFiPIRSF001293 ATP6V0A1, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A0Q9X8P4_DROMO
AccessioniPrimary (citable) accession number: A0A0Q9X8P4
Entry historyiIntegrated into UniProtKB/TrEMBL: January 20, 2016
Last sequence update: January 20, 2016
Last modified: November 7, 2018
This is version 14 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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