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Protein

Chromosomal replication initiator protein DnaA

Gene

dnaA

Organism
Cellulomonas sp. Root930
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.UniRule annotation

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi211 – 218ATPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingUniRule annotationSAAS annotation
Biological processDNA replicationUniRule annotationSAAS annotation
LigandATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Chromosomal replication initiator protein DnaAUniRule annotationSAAS annotation
Gene namesi
Name:dnaAUniRule annotation
ORF Names:ASE38_04540Imported
OrganismiCellulomonas sp. Root930Imported
Taxonomic identifieri1736609 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaMicrococcalesCellulomonadaceaeCellulomonas
Proteomesi
  • UP000051941 Componenti: Unassembled WGS sequence

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini203 – 331AAAInterPro annotationAdd BLAST129
Domaini415 – 484Bac_DnaA_CInterPro annotationAdd BLAST70

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili484 – 504Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the DnaA family.UniRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysis

Family and domain databases

CDDicd06571 Bac_DnaA_C, 1 hit
Gene3Di1.10.1750.10, 1 hit
HAMAPiMF_00377 DnaA_bact, 1 hit
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR001957 Chromosome_initiator_DnaA
IPR020591 Chromosome_initiator_DnaA-like
IPR018312 Chromosome_initiator_DnaA_CS
IPR013317 DnaA
IPR013159 DnaA_C
IPR027417 P-loop_NTPase
IPR010921 Trp_repressor/repl_initiator
PANTHERiPTHR30050:SF2 PTHR30050:SF2, 1 hit
PfamiView protein in Pfam
PF00308 Bac_DnaA, 1 hit
PF08299 Bac_DnaA_C, 1 hit
PRINTSiPR00051 DNAA
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SM00760 Bac_DnaA_C, 1 hit
SUPFAMiSSF48295 SSF48295, 1 hit
SSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00362 DnaA, 1 hit
PROSITEiView protein in PROSITE
PS01008 DNAA, 1 hit

Sequencei

Sequence statusi: Complete.

A0A0Q9CXK2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSQDEELSRV WGHVVSTLES SPDITPRQIA FVRLARPLGL LDGTLLLAVG
60 70 80 90 100
NDLTKDYLES RVRGEVTGAL STALGREARF AITVDPELAE DAPPALRVVA
110 120 130 140 150
PAQDHEPYSP SHDAREADEA DARREARPDL SLVPDDDDEE PNHGGSARDR
160 170 180 190 200
RYPGRNDDRP NRRQPAEPAR LNPKYLFETF VIGSSNRFAH AAAVAVAEAP
210 220 230 240 250
AKAYNPLFIY GDSGLGKTHL LHAIGHYAQN LYPSVRVRYV NSEEFTNDFI
260 270 280 290 300
NSISEGKAGA FQRRYREVDV LLIDDIQFLQ GKEQTMEEFF HTFNTLHNAN
310 320 330 340 350
KQVVITSDLP PKQLNGFEDR MRSRFEWGLI TDVQPPDLET RIAILRKKAG
360 370 380 390 400
SERLEAPPDV LEYIASKIST NIRELEGALI RVTAFANLNR QQVDLSLAEI
410 420 430 440 450
VLKDLITDDQ TTEITATQVI GQTAAYFGLS IDDLCGSSRS RVLVTARQIA
460 470 480 490 500
MYLCRELTDL SLPKIGQAFG GRDHTTVMHA NRKIRELMAE RRSIYNQVTE
510
LTNRIKQQNR G
Length:511
Mass (Da):57,209
Last modified:January 20, 2016 - v1
Checksum:i1A93A8C2999D150A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LMJI01000001 Genomic DNA Translation: KRD43506.1

Genome annotation databases

EnsemblBacteriaiKRD43506; KRD43506; ASE38_04540

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LMJI01000001 Genomic DNA Translation: KRD43506.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiKRD43506; KRD43506; ASE38_04540

Family and domain databases

CDDicd06571 Bac_DnaA_C, 1 hit
Gene3Di1.10.1750.10, 1 hit
HAMAPiMF_00377 DnaA_bact, 1 hit
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR001957 Chromosome_initiator_DnaA
IPR020591 Chromosome_initiator_DnaA-like
IPR018312 Chromosome_initiator_DnaA_CS
IPR013317 DnaA
IPR013159 DnaA_C
IPR027417 P-loop_NTPase
IPR010921 Trp_repressor/repl_initiator
PANTHERiPTHR30050:SF2 PTHR30050:SF2, 1 hit
PfamiView protein in Pfam
PF00308 Bac_DnaA, 1 hit
PF08299 Bac_DnaA_C, 1 hit
PRINTSiPR00051 DNAA
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SM00760 Bac_DnaA_C, 1 hit
SUPFAMiSSF48295 SSF48295, 1 hit
SSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00362 DnaA, 1 hit
PROSITEiView protein in PROSITE
PS01008 DNAA, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A0Q9CXK2_9CELL
AccessioniPrimary (citable) accession number: A0A0Q9CXK2
Entry historyiIntegrated into UniProtKB/TrEMBL: January 20, 2016
Last sequence update: January 20, 2016
Last modified: September 12, 2018
This is version 30 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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