UniProtKB - A0A0Q1D0R6 (A0A0Q1D0R6_9ACTN)
Protein
UvrABC system protein A
Gene
uvrA
Organism
Frankia sp. ACN1ag
Status
Functioni
The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.UniRule annotationSAAS annotation
Caution
Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 32 – 39 | ATPUniRule annotation | 8 | |
Nucleotide bindingi | 646 – 653 | ATPUniRule annotation | 8 | |
Zinc fingeri | 745 – 771 | C4-typeUniRule annotationAdd BLAST | 27 |
GO - Molecular functioni
- ATPase activity Source: InterPro
- ATP binding Source: UniProtKB-UniRule
- DNA binding Source: UniProtKB-UniRule
- excinuclease ABC activity Source: UniProtKB-UniRule
- zinc ion binding Source: UniProtKB-UniRule
GO - Biological processi
- nucleotide-excision repair Source: UniProtKB-UniRule
- SOS response Source: UniProtKB-UniRule
Keywordsi
Molecular function | DNA-bindingUniRule annotationSAAS annotation, Excision nucleaseUniRule annotationSAAS annotation |
Biological process | DNA damage, DNA excisionUniRule annotationSAAS annotation, DNA repair, SOS responseUniRule annotation |
Ligand | ATP-bindingUniRule annotationSAAS annotation, Metal-binding, Nucleotide-binding, Zinc |
Names & Taxonomyi
Protein namesi | Recommended name: UvrABC system protein AUniRule annotationSAAS annotationShort name: UvrA proteinUniRule annotation Alternative name(s): Excinuclease ABC subunit AUniRule annotation |
Gene namesi | Name:uvrAUniRule annotation ORF Names:UK82_16215Imported |
Organismi | Frankia sp. ACN1agImported |
Taxonomic identifieri | 102891 [NCBI] |
Taxonomic lineagei | Bacteria › Actinobacteria › Frankiales › Frankiaceae › Frankia › unclassified Frankia |
Proteomesi |
|
Subcellular locationi
- Cytoplasm UniRule annotationSAAS annotation
GO - Cellular componenti
- cytoplasm Source: UniProtKB-SubCell
- excinuclease repair complex Source: InterPro
Keywords - Cellular componenti
CytoplasmUniRule annotationSAAS annotationInteractioni
Subunit structurei
Forms a heterotetramer with UvrB during the search for lesions.
UniRule annotationSAAS annotationFamily & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 604 – 942 | ABC transporterInterPro annotationAdd BLAST | 339 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 954 – 976 | DisorderedSequence analysisAdd BLAST | 23 |
Sequence similaritiesi
Zinc finger
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Zinc fingeri | 745 – 771 | C4-typeUniRule annotationAdd BLAST | 27 |
Keywords - Domaini
RepeatUniRule annotationSAAS annotation, Zinc-fingerUniRule annotationSAAS annotationFamily and domain databases
HAMAPi | MF_00205 UvrA, 1 hit |
InterProi | View protein in InterPro IPR003439 ABC_transporter-like IPR017871 ABC_transporter_CS IPR027417 P-loop_NTPase IPR004602 UvrA IPR041552 UvrA_DNA-bd IPR041102 UvrA_inter |
Pfami | View protein in Pfam PF00005 ABC_tran, 1 hit PF17755 UvrA_DNA-bind, 1 hit PF17760 UvrA_inter, 1 hit |
SUPFAMi | SSF52540 SSF52540, 2 hits |
TIGRFAMsi | TIGR00630 uvra, 1 hit |
PROSITEi | View protein in PROSITE PS00211 ABC_TRANSPORTER_1, 2 hits PS50893 ABC_TRANSPORTER_2, 1 hit |
i Sequence
Sequence statusi: Complete.
A0A0Q1D0R6-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MADRLVVRGA REHNLRDVDL DLPRDGLIVF TGMSGSGKSS LAFDTIFAEG
60 70 80 90 100
QRRYVESLSA YARQFLGQMD KPDVDFIEGL SPAVSIDQKS TSRNPRSTVG
110 120 130 140 150
TITEVYDYLR LLFARAXRPH CPKCGRPISR QTPQQIVDRL LELPEGTRFQ
160 170 180 190 200
VLAPVVRGRK GEYLDLFAEL QSSGFARARV DGTVVALTDV PKLEKQRKHT
210 220 230 240 250
IEVVVDRLAA KESAKRRLTD SVETALRLGG GLVLVDFVDR AADDPERERM
260 270 280 290 300
YSEHLACLYD DLSFEELEPR SFSFNSPYGA CPDCTGIGTR KEVDPELVVP
310 320 330 340 350
DPTLSLAQGA VAPWAGGHNK EYFERLLTAL AEDLSFRMDT PWEGLPERAR
360 370 380 390 400
TAVLHGSGET EIHVGYTNRY GRKRXYYTSF EGVIGFIGRR HREAESDSSR
410 420 430 440 450
ERYEGYMRDV PCPACRGARL KPESLAVTVG GRSIAEVAGM AIGECAEFLR
460 470 480 490 500
GLELSERERT IAGRVLKEVD ARLTFLLDVG LDYLSLDRAA GTLAGGEAQR
510 520 530 540 550
IRLATQIGSG LVGVLYVLDE PSIGLHQRDN RRLIQTLLRL RDLGNTLIVV
560 570 580 590 600
EHDEDTIRAS DWVVDIGPGA GEHGGRVVVS GPVAELLASE ESMTGAYLSG
610 620 630 640 650
RRQIPVPDIR RVPTKGRALT VHAAREHNLR DVTVSFPLGC FVAVTGVSGS
660 670 680 690 700
GKSTLVNDIL AAVLANKLNG AREVPGRHRT VSGLDHLDKA VRVDQSPIGR
710 720 730 740 750
TPRSNPATYT GVFDHIRRLF AETTEAKVRG YLPGRFSFNV KGGRCEACSG
760 770 780 790 800
DGTIKIEMNF LPDVYVPCEV CHGARYNRET LEVHYKGRNI AEVLDMPIEE
810 820 830 840 850
AAEFFAAVPA IARHLRTLND VGLGYVRLGQ SAPTLSGGEA QRVKLASELQ
860 870 880 890 900
RRSTGRTVYV LDEPTTGLHF EDIRKLLGVX GRLVDAGNTV IVIEHNLDVI
910 920 930 940 950
KTADWIIDMG PEGGTGGGRV VAQGSPETVA AVEESHTAVF LREILGDRVP
960 970
AAGGAAAEAG GGGGARRRRL AEAAAR
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | LJPA01000016 Genomic DNA Translation: KQC37268.1 |
RefSeqi | WP_055407975.1, NZ_LJPA01000016.1 |
Genome annotation databases
EnsemblBacteriai | KQC37268; KQC37268; UK82_16215 |
PATRICi | fig|102891.4.peg.3689 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | LJPA01000016 Genomic DNA Translation: KQC37268.1 |
RefSeqi | WP_055407975.1, NZ_LJPA01000016.1 |
3D structure databases
ModBasei | Search... |
Genome annotation databases
EnsemblBacteriai | KQC37268; KQC37268; UK82_16215 |
PATRICi | fig|102891.4.peg.3689 |
Family and domain databases
HAMAPi | MF_00205 UvrA, 1 hit |
InterProi | View protein in InterPro IPR003439 ABC_transporter-like IPR017871 ABC_transporter_CS IPR027417 P-loop_NTPase IPR004602 UvrA IPR041552 UvrA_DNA-bd IPR041102 UvrA_inter |
Pfami | View protein in Pfam PF00005 ABC_tran, 1 hit PF17755 UvrA_DNA-bind, 1 hit PF17760 UvrA_inter, 1 hit |
SUPFAMi | SSF52540 SSF52540, 2 hits |
TIGRFAMsi | TIGR00630 uvra, 1 hit |
PROSITEi | View protein in PROSITE PS00211 ABC_TRANSPORTER_1, 2 hits PS50893 ABC_TRANSPORTER_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | A0A0Q1D0R6_9ACTN | |
Accessioni | A0A0Q1D0R6Primary (citable) accession number: A0A0Q1D0R6 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | January 20, 2016 |
Last sequence update: | January 20, 2016 | |
Last modified: | November 13, 2019 | |
This is version 20 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |