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Protein

Succinylglutamate desuccinylase

Gene

astE

Organism
Pseudomonas syringae pv. delphinii
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Transforms N2-succinylglutamate into succinate and glutamate.UniRule annotationSAAS annotation

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

N-succinyl-L-glutamate + H2O = succinate + L-glutamate.UniRule annotationSAAS annotation

Cofactori

Zn2+UniRule annotationNote: Binds 1 zinc ion per subunit.UniRule annotation

Pathwayi: L-arginine degradation via AST pathway

This protein is involved in step 5 of the subpathway that synthesizes L-glutamate and succinate from L-arginine.UniRule annotationSAAS annotation
Proteins known to be involved in the 5 steps of the subpathway in this organism are:
  1. Arginine N-succinyltransferase (ALO72_03015), Arginine N-succinyltransferase (ALO72_03014)
  2. N-succinylarginine dihydrolase (astB)
  3. no protein annotated in this organism
  4. N-succinylglutamate 5-semialdehyde dehydrogenase (astD)
  5. Succinylglutamate desuccinylase (astE)
This subpathway is part of the pathway L-arginine degradation via AST pathway, which is itself part of Amino-acid degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes L-glutamate and succinate from L-arginine, the pathway L-arginine degradation via AST pathway and in Amino-acid degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi67ZincUniRule annotation1
Metal bindingi70ZincUniRule annotation1
Metal bindingi159ZincUniRule annotation1
Active sitei223UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseUniRule annotationSAAS annotation
Biological processArginine metabolismUniRule annotationSAAS annotation
LigandMetal-bindingUniRule annotationSAAS annotation, ZincUniRule annotationSAAS annotation

Enzyme and pathway databases

UniPathwayiUPA00185; UER00283

Names & Taxonomyi

Protein namesi
Recommended name:
Succinylglutamate desuccinylaseUniRule annotationSAAS annotation (EC:3.5.1.96UniRule annotationSAAS annotation)
Gene namesi
Name:astEUniRule annotation
ORF Names:ALO72_04774Imported
OrganismiPseudomonas syringae pv. delphiniiImported
Taxonomic identifieri192088 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000050318 Componenti: Unassembled WGS sequence

Family & Domainsi

Sequence similaritiesi

Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.UniRule annotationSAAS annotation

Family and domain databases

CDDicd03855 M14_ASTE, 1 hit
HAMAPiMF_00767 Arg_catab_AstE, 1 hit
InterProiView protein in InterPro
IPR007036 Aste_AspA
IPR016681 SuccinylGlu_desuccinylase
PfamiView protein in Pfam
PF04952 AstE_AspA, 1 hit
PIRSFiPIRSF017020 AstE, 1 hit
TIGRFAMsiTIGR03242 arg_catab_astE, 1 hit

Sequencei

Sequence statusi: Complete.

A0A0P9TQ69-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQPLRKRAML ALGKLLELTL AGREPAEKTQ LTVEGVRMRW LAEGALEVRP
60 70 80 90 100
PQARDNGTDL LLSAGIHGNE TAPIELLDEL IRSIARGDLK PRARILFLFG
110 120 130 140 150
NPAAMRLGAR YVEQDVNRLF NGRHEQSGGA EALRACELER LAASFFSLPD
160 170 180 190 200
RYRLHYDLHT AIRGSKIEQF ALYPWKEGRQ HSRFELARLR AAGMRAVLLQ
210 220 230 240 250
NKPSIVFSAY TYEQLGAEAF TLELGKARPF GQNQHVNLAP LRLRLEQIIE
260 270 280 290 300
GSEPEPDESL EGLQLFSVAR EVIKRSDAFT FNLADDVENF SELEKGYVLA
310 320 330 340
EDVSDSRWVV KEEGARIIFP NPKVKNGLRA GIVIVPADAD GLG
Length:343
Mass (Da):38,347
Last modified:January 20, 2016 - v1
Checksum:iC890E345152B3335
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LJQH01000331 Genomic DNA Translation: KPX15448.1

Genome annotation databases

EnsemblBacteriaiKPX15448; KPX15448; ALO72_04774
PATRICifig|192088.3.peg.4663

Similar proteinsi

Entry informationi

Entry nameiA0A0P9TQ69_9PSED
AccessioniPrimary (citable) accession number: A0A0P9TQ69
Entry historyiIntegrated into UniProtKB/TrEMBL: January 20, 2016
Last sequence update: January 20, 2016
Last modified: September 27, 2017
This is version 11 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

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