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Protein

Inhibin alpha chain

Gene

inha

Organism
Scleropages formosus (Asian bonytongue)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionGrowth factorUniRule annotationSAAS annotation, HormoneUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Inhibin alpha chainUniRule annotation
Gene namesi
Name:inhaImported
ORF Names:Z043_114255Imported
OrganismiScleropages formosus (Asian bonytongue)Imported
Taxonomic identifieri113540 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOsteoglossocephalaOsteoglossomorphaOsteoglossiformesOsteoglossidaeScleropages
Proteomesi
  • UP000034805 Componenti: Unassembled WGS sequence
  • UP000192224 Componenti: Genome assembly

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

SecretedUniRule annotationSAAS annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 24Sequence analysisAdd BLAST24
ChainiPRO_501062752625 – 340Inhibin alpha chainSequence analysisAdd BLAST316

Keywords - PTMi

Disulfide bondSAAS annotation

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini224 – 340TGF_BETA_2InterPro annotationAdd BLAST117

Sequence similaritiesi

Belongs to the TGF-beta family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

KOiK05500

Family and domain databases

Gene3Di2.10.90.10, 1 hit
InterProiView protein in InterPro
IPR029034 Cystine-knot_cytokine
IPR017175 Inhibin_asu
IPR001839 TGF-b_C
IPR015615 TGF-beta-rel
PANTHERiPTHR11848 PTHR11848, 1 hit
PTHR11848:SF117 PTHR11848:SF117, 1 hit
PfamiView protein in Pfam
PF00019 TGF_beta, 1 hit
PIRSFiPIRSF037328 Inhibin_alpha_subunit, 1 hit
SMARTiView protein in SMART
SM00204 TGFB, 1 hit
SUPFAMiSSF57501 SSF57501, 1 hit
PROSITEiView protein in PROSITE
PS51362 TGF_BETA_2, 1 hit

Sequencei

Sequence statusi: Complete.

A0A0P7TZV0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSERHLRLLI FALVPLVLWV PTRALACEEA GLPRNVVVEW FKQRVLDVLG
60 70 80 90 100
LKEPPVSGVV GPPQPLMSRV GRAAWAEKRR SHEETSQVIL FPSSDSTCAH
110 120 130 140 150
TLGFPVREGS SHFTYYFQLS THGQETVVTS AHFWFYAGEG AVSSNASAPL
160 170 180 190 200
YILTTQQQLI HVAEEPESRI ADGWTTYHVG RRLYPSIAEG PFMVQVRCPT
210 220 230 240 250
CSCQADADKT PFLHLHTRSR GLERSRRAPI PWSPSAIDLL QRPSRDKHDF
260 270 280 290 300
GDCRRTELNI SFEDLGWDNW IVHPKVLTFS YCHGNCTSRD RVTTVLGLRQ
310 320 330 340
CCAPVPETMK SLHFHTTSDG GYSFKYETLP NIVAEDCSCV
Length:340
Mass (Da):38,237
Last modified:January 20, 2016 - v1
Checksum:iB47D3EFD7B8135DB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JARO02005192 Genomic DNA Translation: KPP67179.1
RefSeqiXP_018591037.1, XM_018735521.1

Genome annotation databases

GeneIDi108924272
KEGGisfm:108924272

Similar proteinsi

Entry informationi

Entry nameiA0A0P7TZV0_9TELE
AccessioniPrimary (citable) accession number: A0A0P7TZV0
Entry historyiIntegrated into UniProtKB/TrEMBL: January 20, 2016
Last sequence update: January 20, 2016
Last modified: March 28, 2018
This is version 17 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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