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Protein
Submitted name:

Retinoic acid receptor alpha isoform 1

Gene

RARA

Organism
Heterocephalus glaber (Naked mole rat)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi82 – 157Nuclear receptorPROSITE-ProRule annotationAdd BLAST76

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation, ReceptorUniRule annotationSAAS annotationImported
Biological processTranscription, Transcription regulationPROSITE-ProRule annotationSAAS annotation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Retinoic acid receptor alpha isoform 1Imported
Gene namesi
Name:RARAImported
OrganismiHeterocephalus glaber (Naked mole rat)Imported
Taxonomic identifieri10181 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaHystricomorphaBathyergidaeHeterocephalus

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini82 – 157Nuclear receptorInterPro annotationAdd BLAST76
Domaini180 – 414NR LBDInterPro annotationAdd BLAST235

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.UniRule annotationSAAS annotation

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Family and domain databases

Gene3Di3.30.50.10, 1 hit
InterProiView protein in InterPro
IPR035500 NHR_like_dom_sf
IPR000536 Nucl_hrmn_rcpt_lig-bd
IPR001723 Nuclear_hrmn_rcpt
IPR003078 Retinoic_acid_rcpt
IPR001628 Znf_hrmn_rcpt
IPR013088 Znf_NHR/GATA
PfamiView protein in Pfam
PF00104 Hormone_recep, 1 hit
PF00105 zf-C4, 1 hit
PRINTSiPR01292 RETNOICACIDR
PR00398 STRDHORMONER
PR00047 STROIDFINGER
SMARTiView protein in SMART
SM00430 HOLI, 1 hit
SM00399 ZnF_C4, 1 hit
SUPFAMiSSF48508 SSF48508, 1 hit
PROSITEiView protein in PROSITE
PS51843 NR_LBD, 1 hit
PS00031 NUCLEAR_REC_DBD_1, 1 hit
PS51030 NUCLEAR_REC_DBD_2, 1 hit

Sequencei

Sequence statusi: Complete.

A0A0P6K1Y1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYESVEVGGL APAPNPFLVV DFYNQNRACL VPEKGLPAPG SYSTPLRTAL
60 70 80 90 100
WNGSNHSIET QSSSSEEIVP SPPSPPPLPR IYKPCFVCQD KSSGYHYGVS
110 120 130 140 150
ACEGCKGFFR RSIQKNMVYT CHRDKNCIIN KVTRNRCQYC RLQKCFEVGM
160 170 180 190 200
SKESVRNDRN KKKKEAPKPE SSESCTLTPE VGELIEKVRK AHQETFPALC
210 220 230 240 250
QLGKYTTNNS SEQRVSLDID LWDKFSELST KCIIKTVEFA KQLPGFTTLS
260 270 280 290 300
IADQITLLKA ACLDILILRI CTRYTPEQDT MTFSDGLTLN RTQMHNAGFG
310 320 330 340 350
PLTDLVFAFA NQLLPLEMDD AETGLLSAIC LICGDRQDLE QPERVDLLQE
360 370 380 390 400
PLLEALKVYV RKRRPSRPHM FPKMLMKITD LRSISAKGAE RVITLKMEIP
410 420 430 440 450
GSMPPLIQEM LENSEGLDTL SGQPGGGGRE GGGLATATGS CSPSLSPASN

RSSPATHSP
Length:459
Mass (Da):50,704
Last modified:January 20, 2016 - v1
Checksum:i0A8CF1290BE07EFA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GEBF01006045 Transcribed RNA Translation: JAN97587.1
RefSeqiXP_004859505.1, XM_004859448.2

Genome annotation databases

GeneIDi101722948

Similar proteinsi

Entry informationi

Entry nameiA0A0P6K1Y1_HETGA
AccessioniPrimary (citable) accession number: A0A0P6K1Y1
Entry historyiIntegrated into UniProtKB/TrEMBL: January 20, 2016
Last sequence update: January 20, 2016
Last modified: June 20, 2018
This is version 21 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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