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Protein
Submitted name:

Actin filament-associated protein 1 isoform B

Gene

AFAP1

Organism
Heterocephalus glaber (Naked mole rat)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Actin filament-associated protein 1 isoform BImported
Gene namesi
Name:AFAP1Imported
OrganismiHeterocephalus glaber (Naked mole rat)Imported
Taxonomic identifieri10181 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaHystricomorphaBathyergidaeHeterocephalus

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini152 – 248PHInterPro annotationAdd BLAST97
Domaini345 – 439PHInterPro annotationAdd BLAST95

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili555 – 596Sequence analysisAdd BLAST42
Coiled coili599 – 633Sequence analysisAdd BLAST35

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

KOiK18616

Family and domain databases

Gene3Di2.30.29.30, 2 hits
InterProiView protein in InterPro
IPR030113 AFAP
IPR029907 AFAP-110
IPR011993 PH-like_dom_sf
IPR001849 PH_domain
PANTHERiPTHR14338 PTHR14338, 2 hits
PTHR14338:SF8 PTHR14338:SF8, 2 hits
PfamiView protein in Pfam
PF00169 PH, 2 hits
SMARTiView protein in SMART
SM00233 PH, 2 hits
PROSITEiView protein in PROSITE
PS50003 PH_DOMAIN, 2 hits

Sequencei

Sequence statusi: Complete.

A0A0P6JE75-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEELIVELRL FLELLDHEYL TSTVREKKAV LTNILLRIQS SRGFDVKDHA
60 70 80 90 100
QKPETNSLPA PPQMPLPEIP QPWLPPDSGP PPLPTSSLPE GYYEEAVPLS
110 120 130 140 150
PGKAPEYITA NYDSDAMSSS YESYDEEEED GKGKKARHQW PSEEASMDLV
160 170 180 190 200
KDAKICAFLL RKKRFGQWTK LLCVIKDTKL LCYKSSKDQQ PQMELPLQGC
210 220 230 240 250
SIMYIPKDSK KKKHELKITQ QGTDPLVLAV QSKEQAEQWL KVIKEAYSGC
260 270 280 290 300
SGPSELECPP PASAPLQKAE LEKKLSSERP SSDGEGAMEN GVSCNGKEQV
310 320 330 340 350
KRKKSSKAEA KGTVPKVAGK RITKIIGLGK KKPSTEEQTS SAEEDVPTCG
360 370 380 390 400
YLNVLSNNRW RERWCRVKDN KLIFHKDRAD LKTHIVSIPL RGCEVIPGLD
410 420 430 440 450
SKHPLTFRLL RNGQEVAVLE ASSSEDMGRW IGILLAETGS STDPGALHYD
460 470 480 490 500
YIDVEMSANV IQTAKQTFCF MNRRGLSTSP YLGSAANGYS HPSGTALHYD
510 520 530 540 550
DVPCINGSLK GKKPPAASNG VPGKGKTLSS QQKKADSTAG MKRTPSNADQ
560 570 580 590 600
YKYGKNRVEA DAKRLQTKEE ELLQRKEALR NRLAQLRKER RDLRAAIEVN
610 620 630 640 650
AGRKTQVVLE EKLRKLEEEC KQREAERVSL ELELTEVKES LKKALAGGVT
660 670 680 690 700
LGLAIEPKSG TSSPQSPVFR HRTLENSPVS SCDTSDAEGP LPVNSATVLR
710 720
KSPPAMGSSR CRGHVLRKAK EWELKNGT
Length:728
Mass (Da):80,646
Last modified:January 20, 2016 - v1
Checksum:iADEE2AB8D0153BB3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GEBF01004757 Transcribed RNA Translation: JAN98875.1
RefSeqiXP_004847394.1, XM_004847337.2

Genome annotation databases

GeneIDi101717414
KEGGihgl:101717414

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GEBF01004757 Transcribed RNA Translation: JAN98875.1
RefSeqiXP_004847394.1, XM_004847337.2

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi101717414
KEGGihgl:101717414

Organism-specific databases

CTDi60312

Phylogenomic databases

KOiK18616

Family and domain databases

Gene3Di2.30.29.30, 2 hits
InterProiView protein in InterPro
IPR030113 AFAP
IPR029907 AFAP-110
IPR011993 PH-like_dom_sf
IPR001849 PH_domain
PANTHERiPTHR14338 PTHR14338, 2 hits
PTHR14338:SF8 PTHR14338:SF8, 2 hits
PfamiView protein in Pfam
PF00169 PH, 2 hits
SMARTiView protein in SMART
SM00233 PH, 2 hits
PROSITEiView protein in PROSITE
PS50003 PH_DOMAIN, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiA0A0P6JE75_HETGA
AccessioniPrimary (citable) accession number: A0A0P6JE75
Entry historyiIntegrated into UniProtKB/TrEMBL: January 20, 2016
Last sequence update: January 20, 2016
Last modified: June 20, 2018
This is version 12 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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