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Protein
Submitted name:

High mobility group protein B2

Gene

HMGB2

Organism
Heterocephalus glaber (Naked mole rat)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi9 – 79HMG boxPROSITE-ProRule annotationAdd BLAST71
DNA bindingi96 – 164HMG boxPROSITE-ProRule annotationAdd BLAST69

GO - Molecular functioni

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
High mobility group protein B2Imported
Gene namesi
Name:HMGB2Imported
OrganismiHeterocephalus glaber (Naked mole rat)Imported
Taxonomic identifieri10181 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaHystricomorphaBathyergidaeHeterocephalus

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini9 – 79HMG boxInterPro annotationAdd BLAST71
Domaini96 – 164HMG boxInterPro annotationAdd BLAST69

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili146 – 166Sequence analysisAdd BLAST21
Coiled coili189 – 211Sequence analysisAdd BLAST23

Keywords - Domaini

Coiled coilSequence analysis

Family and domain databases

Gene3Di1.10.30.10, 2 hits
InterProiView protein in InterPro
IPR009071 HMG_box_dom
IPR036910 HMG_box_dom_sf
IPR017967 HMG_boxA_CS
IPR031075 HMGB2
PANTHERiPTHR13711:SF181 PTHR13711:SF181, 1 hit
PfamiView protein in Pfam
PF00505 HMG_box, 1 hit
PF09011 HMG_box_2, 1 hit
SMARTiView protein in SMART
SM00398 HMG, 2 hits
SUPFAMiSSF47095 SSF47095, 2 hits
PROSITEiView protein in PROSITE
PS00353 HMG_BOX_1, 1 hit
PS50118 HMG_BOX_2, 2 hits

Sequencei

Sequence statusi: Complete.

A0A0P6JCW3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGKGDPNKPR GKMSSYAFFV QTCREEHKKK HPDSSVNFAE FSKKCSERWK
60 70 80 90 100
TMSAKEKSKF EDMAKSDKAR YDREMKNYVP PKGGDKKGKK KDPNAPKRPP
110 120 130 140 150
SAFFLFCSEH RPKIKSEHPG LSIGDTAKKL GEMWSEQSAK DKQPYEQKAA
160 170 180 190 200
KLKEKYEKDI AAYRAKGKSE AGKKGPGRPT GSKKKNEPED EEEEEEEEEE
210 220 230 240 250
EEEDGEEIEQ EHEGKKVVVF FTRNGKIIGK KDAVVPSGGF FPTIGMLSCG
260
EKVKVDLHPL SG
Length:262
Mass (Da):29,581
Last modified:January 20, 2016 - v1
Checksum:i647043E6AA5FAEC1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GEBF01001882 Transcribed RNA Translation: JAO01751.1

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GEBF01001882 Transcribed RNA Translation: JAO01751.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di1.10.30.10, 2 hits
InterProiView protein in InterPro
IPR009071 HMG_box_dom
IPR036910 HMG_box_dom_sf
IPR017967 HMG_boxA_CS
IPR031075 HMGB2
PANTHERiPTHR13711:SF181 PTHR13711:SF181, 1 hit
PfamiView protein in Pfam
PF00505 HMG_box, 1 hit
PF09011 HMG_box_2, 1 hit
SMARTiView protein in SMART
SM00398 HMG, 2 hits
SUPFAMiSSF47095 SSF47095, 2 hits
PROSITEiView protein in PROSITE
PS00353 HMG_BOX_1, 1 hit
PS50118 HMG_BOX_2, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiA0A0P6JCW3_HETGA
AccessioniPrimary (citable) accession number: A0A0P6JCW3
Entry historyiIntegrated into UniProtKB/TrEMBL: January 20, 2016
Last sequence update: January 20, 2016
Last modified: December 20, 2017
This is version 10 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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