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Protein

L-lactate dehydrogenase

Gene

lldD

Organism
Pseudomonas syringae pv. lapsa
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain.UniRule annotationSAAS annotation

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

(S)-lactate + an oxidized electron acceptor = pyruvate + a reduced electron acceptor.UniRule annotationSAAS annotation

Cofactori

FMNUniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei24SubstrateUniRule annotation1
Binding sitei106FMNUniRule annotation1
Binding sitei127FMNUniRule annotation1
Binding sitei129SubstrateUniRule annotation1
Binding sitei155FMNUniRule annotation1
Binding sitei164SubstrateUniRule annotation1
Binding sitei251FMNUniRule annotation1
Binding sitei273FMNUniRule annotation1
Active sitei275Proton acceptorUniRule annotation1
Binding sitei278SubstrateUniRule annotation1
Binding sitei330FMNUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi306 – 330FMNUniRule annotationAdd BLAST25
Nucleotide bindingi306 – 310FMNUniRule annotation5

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotationSAAS annotation
LigandFlavoprotein, FMNUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
L-lactate dehydrogenaseUniRule annotationSAAS annotation (EC:1.1.-.-UniRule annotationSAAS annotation)
Gene namesi
Name:lldDUniRule annotation
ORF Names:ALO39_04793Imported
OrganismiPseudomonas syringae pv. lapsaImported
Taxonomic identifieri199201 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonasPseudomonas syringae
Proteomesi
  • UP000050314 Componenti: Unassembled WGS sequence

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membraneSAAS annotation, Cell membrane, Membrane

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 380FMN hydroxy acid dehydrogenaseInterPro annotationAdd BLAST380

Sequence similaritiesi

Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.UniRule annotationSAAS annotation

Family and domain databases

CDDicd02809 alpha_hydroxyacid_oxid_FMN, 1 hit
Gene3Di3.20.20.70, 1 hit
HAMAPiMF_01559 L_lact_dehydr, 1 hit
InterProiView protein in InterPro
IPR013785 Aldolase_TIM
IPR012133 Alpha-hydoxy_acid_DH_FMN
IPR000262 FMN-dep_DH
IPR037396 FMN_HAD
IPR008259 FMN_hydac_DH_AS
IPR020920 LldD
PfamiView protein in Pfam
PF01070 FMN_dh, 1 hit
PIRSFiPIRSF000138 Al-hdrx_acd_dh, 1 hit
PROSITEiView protein in PROSITE
PS00557 FMN_HYDROXY_ACID_DH_1, 1 hit
PS51349 FMN_HYDROXY_ACID_DH_2, 1 hit

Sequencei

Sequence statusi: Complete.

A0A0N8RV19-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MIISSASDYR AAAKRKLPRF LFDYIDGGAY AEHTLRANGS DLADISLRQR
60 70 80 90 100
VLKNVDNVSL ETRLFGESLA MPIVLSPVGL SGMYARRGEV QAAKAAANKR
110 120 130 140 150
IPFCLSTVSV CSIEEVASQS KQVIWFQLYV LKDRGFMKNA LERARAAGVT
160 170 180 190 200
TLVFTVDMPT PGARYRDAHS GMSGPYAAPR RILQAMTKPD WALNVGLLGR
210 220 230 240 250
PHDLGNISRY LGKTTTLEDY VGWLANNFDP SISWKDLEWI REFWQGPMII
260 270 280 290 300
KGILDPQDAR DALSFGADGI VVSNHGGRQL DGALSTAKAL PPIVQAVGSD
310 320 330 340 350
LTVLADSGIR SGLDVVRMLA LGAKGVLLGR SMAYALGADG QRGVENMLDI
360 370 380
FAREMHVAMT LTGVTSIEQI DESILVKSAV
Length:380
Mass (Da):41,200
Last modified:January 20, 2016 - v1
Checksum:i20E18BC63E38FF4B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LJQQ01000049 Genomic DNA Translation: KPX63959.1
RefSeqiWP_057406478.1, NZ_LJQQ01000049.1

Genome annotation databases

EnsemblBacteriaiKPX63959; KPX63959; ALO39_04793
PATRICifig|199201.4.peg.2089

Similar proteinsi

Entry informationi

Entry nameiA0A0N8RV19_PSESX
AccessioniPrimary (citable) accession number: A0A0N8RV19
Entry historyiIntegrated into UniProtKB/TrEMBL: January 20, 2016
Last sequence update: January 20, 2016
Last modified: September 12, 2018
This is version 19 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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