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UniProtKB - A0A0N4SW93 (A0A0N4SW93_MOUSE)
Protein
Submitted name:
C2 domain-containing protein 5
Gene
C2cd5
Organism
Mus musculus (Mouse)
Status
Functioni
GO - Molecular functioni
- calcium-dependent phospholipid binding Source: Ensembl
- calcium ion binding Source: Ensembl
GO - Biological processi
- cellular response to insulin stimulus Source: Ensembl
- intracellular protein transmembrane transport Source: Ensembl
- positive regulation of protein targeting to membrane Source: Ensembl
- positive regulation of vesicle fusion Source: Ensembl
Names & Taxonomyi
Protein namesi | Submitted name: C2 domain-containing protein 5Imported |
Gene namesi | Name:C2cd5Imported |
Organismi | Mus musculus (Mouse)Imported |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:1921991, C2cd5 |
VEuPathDBi | HostDB:ENSMUSG00000030279 |
Subcellular locationi
Cytoskeleton
- centriolar satellite Source: Ensembl
Cytosol
- cytosol Source: Ensembl
Plasma Membrane
- ruffle membrane Source: Ensembl
Other locations
- cell cortex Source: Ensembl
- cytoplasmic vesicle membrane Source: Ensembl
Expressioni
Gene expression databases
Bgeei | ENSMUSG00000030279, Expressed in embryo and 262 other tissues |
ExpressionAtlasi | A0A0N4SW93, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 1 – 109 | C2InterPro annotationAdd BLAST | 109 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 638 – 670 | DisorderedSequence analysisAdd BLAST | 33 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 655 – 670 | Basic and acidic residuesSequence analysisAdd BLAST | 16 |
Phylogenomic databases
GeneTreei | ENSGT00390000000212 |
OMAi | NHLVAPE |
OrthoDBi | 266134at2759 |
Family and domain databases
CDDi | cd08688, C2_KIAA0528-like, 1 hit |
Gene3Di | 2.60.40.150, 1 hit |
InterProi | View protein in InterPro IPR037785, C2_C2CD5 IPR000008, C2_dom IPR035892, C2_domain_sf IPR038983, C2CD5 |
PANTHERi | PTHR37412, PTHR37412, 1 hit |
Pfami | View protein in Pfam PF00168, C2, 1 hit |
SMARTi | View protein in SMART SM00239, C2, 1 hit |
SUPFAMi | SSF49562, SSF49562, 1 hit |
PROSITEi | View protein in PROSITE PS50004, C2, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All
A0A0N4SW93-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MPGKLKVKIV AGRHLPVMDR ASDLTDAFVE VKFGNTTFKT DVYLKSLNPQ
60 70 80 90 100
WNSEWFKFEV DDEDLQDEPL QITVLDHDTY SANDAIGKVY IDIDPLLYSE
110 120 130 140 150
AATVISGWFP IYDTIHGIRG EINVVVKVDL FNDSNRFRQS SCGVKFFCTT
160 170 180 190 200
SIPKCYRAVV IHGFVEELVV NEDPEYQWID RIRTPRASNE ARQRLISLMS
210 220 230 240 250
GELQRKIGLK VLEMRGNAVV GYLQCFDLEG ESGLVVRAIG TACTLDKLSS
260 270 280 290 300
PAAFLPACSS PSRELKESPL VHPPSHGCRS THNSPIHTAT GSRLTQNFSV
310 320 330 340 350
SVPTLIYTGM GSGSAGKEGG PFKALLRQQT QSALEQRGGS PHRFCRRREF
360 370 380 390 400
PFLTLTAFPP GLLVHVGGVV SARSVKLLDR IHNPDEPETR DAWWAEIRQE
410 420 430 440 450
IKSHAKALGC HAVVGYSEST SICEEVCILS ASGTAAVLNP RFLQEGTVEG
460 470 480 490 500
CLEQRIEENL PVGCGFCHIP YDELNMPFPA HLTYCYNCRK QKVPDVLFTT
510 520 530 540 550
IDLPTDAVVV GKGCLIQARL CRLKKKAQAE ANATAISNLL PFMEYEVHTQ
560 570 580 590 600
LMNKLKLKGM NALFGLRIQI TVGETMLMGL ASATGVYLAA LPTPGGIQIA
610 620 630 640 650
GKTPNDGSYE QHISHMQKRI NDTIAKNKEL YEITPPEVSE EMIGSPIPEP
660 670 680 690 700
RQRSRLLRSQ SESSDEVTEL DLSHGKKDAF VLEIDDTDAM EDVHSLLTDA
710 720 730 740 750
PPPSGFYSCN TEIMPGINNW TSEIQMFTSV RVVRLSSLNL TNQALNKNFN
760 770 780 790 800
GLCENLLKSL YFKLRSMTPC CLCHVNFTVS LPEDELIQVT VTAVAITFDK
810 820 830 840 850
NQALQTTKPH VEKSLQRAST DNEELLQFPL ELCSDSLPPH PFPAAKEHLE
860 870 880 890 900
SANSNSGIPA AQRATSVDYS SFADRCSSWI ELIRLKAQTI RRGSIKTTVT
910 920 930 940 950
VEKASAMGDG NFRNRSAPPC ASPTVGVVKM TPLSFIPGAK ITKYLGIINM
960 970 980 990 1000
FFIRETTSLR EEGGVSGFLH AFIAEVFAMV RAHVAALGGN AVVSYIMKQC
1010 1020 1030 1040 1050
VFMENPSKNQ AQCLINVSGD AVVFVRDSDL EVMSSQQPAA NCQPSCTGEV
TT
Computationally mapped potential isoform sequencesi
There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ7TPS5 | C2CD5_MOUSE | C2 domain-containing protein 5 | C2cd5 Cdp138, Kiaa0528 | 1,016 | Annotation score: | ||
E9Q026 | E9Q026_MOUSE | C2 domain-containing protein 5 | C2cd5 5730419I09Rik | 999 | Annotation score: | ||
A0A0N4SVN0 | A0A0N4SVN0_MOUSE | C2 domain-containing protein 5 | C2cd5 | 232 | Annotation score: | ||
A0A0N4SW69 | A0A0N4SW69_MOUSE | C2 domain-containing protein 5 | C2cd5 | 70 | Annotation score: | ||
A0A0N4SW58 | A0A0N4SW58_MOUSE | C2 domain-containing protein 5 | C2cd5 | 181 | Annotation score: |
Sequence databases
RefSeqi | XP_017177289.1, XM_017321800.1 |
Genome annotation databases
Ensembli | ENSMUST00000203673; ENSMUSP00000145425; ENSMUSG00000030279 |
GeneIDi | 74741 |
Similar proteinsi
Cross-referencesi
Sequence databases
RefSeqi | XP_017177289.1, XM_017321800.1 |
3D structure databases
SMRi | A0A0N4SW93 |
ModBasei | Search... |
Proteomic databases
EPDi | A0A0N4SW93 |
jPOSTi | A0A0N4SW93 |
ProteomicsDBi | 359883 |
Protocols and materials databases
Antibodypediai | 24138, 50 antibodies from 19 providers |
DNASUi | 74741 |
Genome annotation databases
Ensembli | ENSMUST00000203673; ENSMUSP00000145425; ENSMUSG00000030279 |
GeneIDi | 74741 |
Organism-specific databases
CTDi | 9847 |
MGIi | MGI:1921991, C2cd5 |
VEuPathDBi | HostDB:ENSMUSG00000030279 |
Phylogenomic databases
GeneTreei | ENSGT00390000000212 |
OMAi | NHLVAPE |
OrthoDBi | 266134at2759 |
Miscellaneous databases
BioGRID-ORCSi | 74741, 5 hits in 64 CRISPR screens |
ChiTaRSi | C2cd5, mouse |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000030279, Expressed in embryo and 262 other tissues |
ExpressionAtlasi | A0A0N4SW93, baseline and differential |
Family and domain databases
CDDi | cd08688, C2_KIAA0528-like, 1 hit |
Gene3Di | 2.60.40.150, 1 hit |
InterProi | View protein in InterPro IPR037785, C2_C2CD5 IPR000008, C2_dom IPR035892, C2_domain_sf IPR038983, C2CD5 |
PANTHERi | PTHR37412, PTHR37412, 1 hit |
Pfami | View protein in Pfam PF00168, C2, 1 hit |
SMARTi | View protein in SMART SM00239, C2, 1 hit |
SUPFAMi | SSF49562, SSF49562, 1 hit |
PROSITEi | View protein in PROSITE PS50004, C2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | A0A0N4SW93_MOUSE | |
Accessioni | A0A0N4SW93Primary (citable) accession number: A0A0N4SW93 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | December 9, 2015 |
Last sequence update: | December 9, 2015 | |
Last modified: | January 19, 2022 | |
This is version 39 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |