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Entry version 19 (07 Oct 2020)
Sequence version 1 (09 Dec 2015)
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Protein

Reverse transcriptase

Gene

RR48_05799

Organism
Papilio machaon (Old World swallowtail butterfly)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Reverse transcriptaseARBA annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:RR48_05799Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPapilio machaon (Old World swallowtail butterfly)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri76193 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaLepidopteraGlossataDitrysiaPapilionoideaPapilionidaePapilioninaePapilio
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000053240 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini214 – 297Peptidase A2InterPro annotationAdd BLAST84
Domaini1220 – 1402Integrase catalyticInterPro annotationAdd BLAST183

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni149 – 169DisorderedSequence analysisAdd BLAST21

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.420.10, 1 hit
3.30.70.270, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR043502, DNA/RNA_pol_sf
IPR040676, DUF5641
IPR001584, Integrase_cat-core
IPR041588, Integrase_H2C2
IPR001995, Peptidase_A2_cat
IPR008737, Peptidase_asp_put
IPR008042, Retrotrans_Pao
IPR043128, Rev_trsase/Diguanyl_cyclase
IPR012337, RNaseH-like_sf
IPR036397, RNaseH_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF05585, DUF1758, 1 hit
PF18701, DUF5641, 1 hit
PF17921, Integrase_H2C2, 1 hit
PF05380, Peptidase_A17, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF53098, SSF53098, 1 hit
SSF56672, SSF56672, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50175, ASP_PROT_RETROV, 1 hit
PS50994, INTEGRASE, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A0N1IGH3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MQDTTGRPKL EIMSDFLRRE LDQLIRFGLS PESCSIQHSP QNSQVNKPYK
60 70 80 90 100
RENIHIVTHS KPNSKVVSTQ KPECAFCKKD HNIKSCSEFK ALSVDERWVW
110 120 130 140 150
LREVKACYRC LKRYSHQWKT CKVNPCGVDG CLLRHHPLLH GKQPASSINT
160 170 180 190 200
TFDTQSAEND HSTTQHEPTS VEKVIISTTS TGVQEPSSIL TMCPRVFLKI
210 220 230 240 250
LPVTVSGPSG SCNVYALLDD GSTATLIDSS IAAQIGATGP HQKITVNGIG
260 270 280 290 300
GLSRNATISY VDFHIKGRHT RDTFLVKNAR AMESLSLRPQ TIRQETIASF
310 320 330 340 350
AHLADLPCNV TYEDATPSVL IGAEHWHLSI SSEVRCGGKN EPVACLTALG
360 370 380 390 400
WVLYGIASSK TKLVEFVNHG VCIEPSDDEK LDSLIREQYK IDSLGISKKE
410 420 430 440 450
TLHSKADKRA VEILEKTARR LPTSGRFEVG MPWRDDIQRI PDSYPQAMSR
460 470 480 490 500
FLSLERRMAK DADFAKAYDV FISNMIAKGY AEECAPESYY ANHIKDKQSS
510 520 530 540 550
FMRLYLPHFG VYHPQKRKLR VVHDAAATNE GVSLNSLLLP GPDLLQPLLG
560 570 580 590 600
ILFRFREGRI ALTADIREMF PQVRIREQDR DALRYLWRSS RDQPIKEFRM
610 620 630 640 650
TAVIFGACCS PFIAQFIKNK NACEHESLFP KAAHAILYNH YMDDYIDSLD
660 670 680 690 700
DVQEAAQLAA DIVTVHNDAC FEIRGWISND PSALKFIPAD LRATQPSSEI
710 720 730 740 750
NVGSCSANNI RALGVLWNPT TDNLGFRSGL GETFPNPLTK RKVLCHLMRV
760 770 780 790 800
YDPLGLLAPI VVKGRILFQQ TWRSNVDWDT EFQPTEALRW SDWFQELSKV
810 820 830 840 850
TSLEIPRWYS NFKNSEPTQR ELHVFADASE LAYACVAYWR LLYSDGSIEL
860 870 880 890 900
SLISSKARVT PLKPTSIPRL ELQAALIASR LAVTIKDSHR KQPTHTFFWT
910 920 930 940 950
DSMTVLQWLR SDARSFKPFV AHRLGEIIEN SCVRDWRWVP TDLNVADDAT
960 970 980 990 1000
RTRSINLDAS HRWFRGPSFL FKSFEDWPTE PRYASPNTDE LKTNSFELVG
1010 1020 1030 1040 1050
LTSFVEELPT PVTAIFANFS NWQRLLRATA RVLQAAAKFG VILASFRNSK
1060 1070 1080 1090 1100
LKGDVVCARH PSASTTLPPL SADLIKAAER QILQRTQLES FSIEFLHVLN
1110 1120 1130 1140 1150
SKPIPPNSRL RKLSPALGED KLLRLAGRIK AAEGIDPDTR FPILLDGRHP
1160 1170 1180 1190 1200
IVRLLVQFYH RKAGHANYEL VVNELRQKYW LLGLRNTVRT VAKECLLCRI
1210 1220 1230 1240 1250
RKSLPVNPKT GDLPPERLAH HRRPFTFTGL DYFGPISVTI GRRHEKRYVA
1260 1270 1280 1290 1300
LFTCLTVRAL HLEMVHSLST DSAIMAIRRF IARRGSPNTI FSDNGTCFVG
1310 1320 1330 1340 1350
ANRILREFYG VNVEDFMSTQ GIRWKFTPPA APNFGGCWER LVRSVKVALN
1360 1370 1380 1390 1400
ATLTERAPKE ETLSSLLAEA EAIVNSRPLT HVSTDPDDPT TLTPFHFLIG
1410 1420 1430 1440 1450
SSSMQTLPTA LNDHDLVSRS EWRKALRLAD HFWSRWMREV LPTLQPREQP
1460 1470 1480 1490 1500
RGNRSSTALQ EGDIVIIADS NLPRGTWPRG RVAKTYCGKD QVIRVVDVTT
1510
AGGMLRRPVR KLVRLST
Length:1,517
Mass (Da):171,377
Last modified:December 9, 2015 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i70691729BF14CB49
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
KQ459986 Genomic DNA Translation: KPJ18861.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KQ459986 Genomic DNA Translation: KPJ18861.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Family and domain databases

Gene3Di3.30.420.10, 1 hit
3.30.70.270, 1 hit
InterProiView protein in InterPro
IPR043502, DNA/RNA_pol_sf
IPR040676, DUF5641
IPR001584, Integrase_cat-core
IPR041588, Integrase_H2C2
IPR001995, Peptidase_A2_cat
IPR008737, Peptidase_asp_put
IPR008042, Retrotrans_Pao
IPR043128, Rev_trsase/Diguanyl_cyclase
IPR012337, RNaseH-like_sf
IPR036397, RNaseH_sf
PfamiView protein in Pfam
PF05585, DUF1758, 1 hit
PF18701, DUF5641, 1 hit
PF17921, Integrase_H2C2, 1 hit
PF05380, Peptidase_A17, 1 hit
SUPFAMiSSF53098, SSF53098, 1 hit
SSF56672, SSF56672, 1 hit
PROSITEiView protein in PROSITE
PS50175, ASP_PROT_RETROV, 1 hit
PS50994, INTEGRASE, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A0N1IGH3_PAPMA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A0N1IGH3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: December 9, 2015
Last sequence update: December 9, 2015
Last modified: October 7, 2020
This is version 19 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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