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Entry version 27 (07 Apr 2021)
Sequence version 1 (11 Nov 2015)
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Protein

Isoprenyl transferase

Gene

BBL306_1890

Organism
Bifidobacterium longum subsp. longum
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.UniRule annotation

<p>This subsection of the 'Function' section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Mg2+UniRule annotationNote: Binds 2 magnesium ions per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei43UniRule annotation1
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the 'Description' field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi43MagnesiumUniRule annotation1
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei48SubstrateUniRule annotation1
Binding sitei56SubstrateUniRule annotation1
Binding sitei60SubstrateUniRule annotation1
Active sitei91Proton acceptorUniRule annotation1
Binding sitei92SubstrateUniRule annotation1
Binding sitei94SubstrateUniRule annotation1
Binding sitei211SubstrateUniRule annotation1
Metal bindingi230MagnesiumUniRule annotation1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionTransferaseUniRule annotationARBA annotation
LigandMagnesiumUniRule annotation, Metal-bindingUniRule annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Isoprenyl transferaseUniRule annotation (EC:2.5.1.-UniRule annotation)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:BBL306_1890Imported, BLOI2_0127Imported, MCC10002_1672Imported, MCC10003_1374Imported, MCC10004_1551Imported, MCC10007_1319Imported, MCC10008_1454Imported, MCC10009_1376Imported, MCC10012_1380Imported, MCC10015_1473Imported, MCC10040_1300Imported, MCC10043_1559Imported, MCC10044_1440Imported, MCC10070_1466Imported, MCC10075_1401Imported, MCC10076_1516Imported, MCC10080_1499Imported, MCC10094_1560Imported, MCC10096_1596Imported, MCC10100_1381Imported, MCC10102_1523Imported, MCC10103_1782Imported, MCC10113_1442Imported, MCC10114_1391Imported, MCC10115_1391Imported, MCC10116_1831Imported, MCC10120_1617Imported, MCC10123_1501Imported, MCC10128_1576Imported, MCC10212_1482Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiBifidobacterium longum subsp. longumImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri1679 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaActinobacteriaBifidobacterialesBifidobacteriaceaeBifidobacterium
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000291299 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence
  • UP000292787 Componenti: Unassembled WGS sequence
  • UP000292966 Componenti: Unassembled WGS sequence
  • UP000292097 Componenti: Unassembled WGS sequence
  • UP000291881 Componenti: Unassembled WGS sequence
  • UP000293475 Componenti: Unassembled WGS sequence
  • UP000293683 Componenti: Unassembled WGS sequence
  • UP000293247 Componenti: Unassembled WGS sequence
  • UP000291214 Componenti: Unassembled WGS sequence
  • UP000292478 Componenti: Unassembled WGS sequence
  • UP000293441 Componenti: Unassembled WGS sequence
  • UP000292751 Componenti: Unassembled WGS sequence
  • UP000293701 Componenti: Unassembled WGS sequence
  • UP000292260 Componenti: Unassembled WGS sequence
  • UP000291602 Componenti: Unassembled WGS sequence
  • UP000037245 Componenti: Unassembled WGS sequence
  • UP000292692 Componenti: Unassembled WGS sequence
  • UP000292528 Componenti: Unassembled WGS sequence
  • UP000293591 Componenti: Unassembled WGS sequence
  • UP000291713 Componenti: Unassembled WGS sequence
  • UP000292770 Componenti: Unassembled WGS sequence
  • UP000292023 Componenti: Unassembled WGS sequence
  • UP000291814 Componenti: Unassembled WGS sequence
  • UP000293461 Componenti: Unassembled WGS sequence
  • UP000294075 Componenti: Unassembled WGS sequence
  • UP000294241 Componenti: Unassembled WGS sequence
  • UP000065375 Componenti: Chromosome
  • UP000292932 Componenti: Unassembled WGS sequence
  • UP000293319 Componenti: Unassembled WGS sequence
  • UP000292241 Componenti: Unassembled WGS sequence

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homodimer.

UniRule annotation

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
A0A0M0VPJ9

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni44 – 47Substrate bindingUniRule annotation4
Regioni88 – 90Substrate bindingUniRule annotation3
Regioni217 – 219Substrate bindingUniRule annotation3

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the UPP synthase family.UniRule annotation

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00475, Cis_IPPS, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.40.1180.10, 1 hit

HAMAP database of protein families

More...
HAMAPi
MF_01139, ISPT, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001441, UPP_synth-like
IPR018520, UPP_synth-like_CS
IPR036424, UPP_synth-like_sf

The PANTHER Classification System

More...
PANTHERi
PTHR10291, PTHR10291, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01255, Prenyltransf, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF64005, SSF64005, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR00055, uppS, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS01066, UPP_SYNTHASE, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A0M0VPJ9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSMAFENVDY TSLDIPAAPF SDPARIPDFP KNKVPRHIGV IMDGNGRWAK
60 70 80 90 100
QRGMVRTNGH QAAEPVVFDT IAGAIEAGVR YLSLYTFSTE NWKRSPQEVR
110 120 130 140 150
FLMGFSREII HRRVEQMDEW GVRVRWSGRR PKLWKSVIDE LEAAEERTKN
160 170 180 190 200
NKVIDVVFCI NYGGRAEIAD ACAAIAREVR DGKISGDRVT EKMIADHLYN
210 220 230 240 250
PDIPDCDLVI RTSGEQRTSN FLPWEAAYAE LDFVPELFPD CGRDVLWRSI
260
DHYIHRDRRF GGVK
Length:264
Mass (Da):30,244
Last modified:November 11, 2015 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iAECEAC1C9E1366C7
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CP011965 Genomic DNA Translation: ALO75419.1
LFDU01000001 Genomic DNA Translation: KOP63573.1
SHPM01000032 Genomic DNA Translation: TCD73049.1
SHPN01000039 Genomic DNA Translation: TCD73846.1
SHPO01000022 Genomic DNA Translation: TCD77351.1
SHPQ01000027 Genomic DNA Translation: TCD81293.1
SHPR01000034 Genomic DNA Translation: TCD83373.1
SHPS01000030 Genomic DNA Translation: TCD85081.1
SHPV01000039 Genomic DNA Translation: TCD91795.1
SHPX01000031 Genomic DNA Translation: TCD96650.1
SHQR01000019 Genomic DNA Translation: TCE35881.1
SHQU01000031 Genomic DNA Translation: TCE39866.1
SHQV01000019 Genomic DNA Translation: TCE43368.1
SHRR01000023 Genomic DNA Translation: TCE84811.1
SHRW01000028 Genomic DNA Translation: TCE95300.1
SHRX01000023 Genomic DNA Translation: TCE97238.1
SHSB01000027 Genomic DNA Translation: TCF03439.1
SHSN01000011 Genomic DNA Translation: TCF27082.1
SHSP01000015 Genomic DNA Translation: TCF30851.1
SHST01000027 Genomic DNA Translation: TCF38504.1
SHSV01000026 Genomic DNA Translation: TCF44294.1
SHSW01000009 Genomic DNA Translation: TCF44785.1
SHTC01000021 Genomic DNA Translation: TCF57538.1
SHTD01000027 Genomic DNA Translation: TCF60304.1
SHTE01000029 Genomic DNA Translation: TCF62501.1
SHTF01000024 Genomic DNA Translation: TCF62804.1
SHTK01000020 Genomic DNA Translation: TCF74638.1
SHTO01000025 Genomic DNA Translation: TCF82146.1
SHTQ01000011 Genomic DNA Translation: TCF86790.1
SHTU01000023 Genomic DNA Translation: TCF94698.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
ALO75419; ALO75419; BBL306_1890
KOP63573; KOP63573; BLOI2_0127

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|1679.10.peg.2067

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP011965 Genomic DNA Translation: ALO75419.1
LFDU01000001 Genomic DNA Translation: KOP63573.1
SHPM01000032 Genomic DNA Translation: TCD73049.1
SHPN01000039 Genomic DNA Translation: TCD73846.1
SHPO01000022 Genomic DNA Translation: TCD77351.1
SHPQ01000027 Genomic DNA Translation: TCD81293.1
SHPR01000034 Genomic DNA Translation: TCD83373.1
SHPS01000030 Genomic DNA Translation: TCD85081.1
SHPV01000039 Genomic DNA Translation: TCD91795.1
SHPX01000031 Genomic DNA Translation: TCD96650.1
SHQR01000019 Genomic DNA Translation: TCE35881.1
SHQU01000031 Genomic DNA Translation: TCE39866.1
SHQV01000019 Genomic DNA Translation: TCE43368.1
SHRR01000023 Genomic DNA Translation: TCE84811.1
SHRW01000028 Genomic DNA Translation: TCE95300.1
SHRX01000023 Genomic DNA Translation: TCE97238.1
SHSB01000027 Genomic DNA Translation: TCF03439.1
SHSN01000011 Genomic DNA Translation: TCF27082.1
SHSP01000015 Genomic DNA Translation: TCF30851.1
SHST01000027 Genomic DNA Translation: TCF38504.1
SHSV01000026 Genomic DNA Translation: TCF44294.1
SHSW01000009 Genomic DNA Translation: TCF44785.1
SHTC01000021 Genomic DNA Translation: TCF57538.1
SHTD01000027 Genomic DNA Translation: TCF60304.1
SHTE01000029 Genomic DNA Translation: TCF62501.1
SHTF01000024 Genomic DNA Translation: TCF62804.1
SHTK01000020 Genomic DNA Translation: TCF74638.1
SHTO01000025 Genomic DNA Translation: TCF82146.1
SHTQ01000011 Genomic DNA Translation: TCF86790.1
SHTU01000023 Genomic DNA Translation: TCF94698.1

3D structure databases

SMRiA0A0M0VPJ9
ModBaseiSearch...

Genome annotation databases

EnsemblBacteriaiALO75419; ALO75419; BBL306_1890
KOP63573; KOP63573; BLOI2_0127
PATRICifig|1679.10.peg.2067

Family and domain databases

CDDicd00475, Cis_IPPS, 1 hit
Gene3Di3.40.1180.10, 1 hit
HAMAPiMF_01139, ISPT, 1 hit
InterProiView protein in InterPro
IPR001441, UPP_synth-like
IPR018520, UPP_synth-like_CS
IPR036424, UPP_synth-like_sf
PANTHERiPTHR10291, PTHR10291, 1 hit
PfamiView protein in Pfam
PF01255, Prenyltransf, 1 hit
SUPFAMiSSF64005, SSF64005, 1 hit
TIGRFAMsiTIGR00055, uppS, 1 hit
PROSITEiView protein in PROSITE
PS01066, UPP_SYNTHASE, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A0M0VPJ9_BIFLN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A0M0VPJ9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 11, 2015
Last sequence update: November 11, 2015
Last modified: April 7, 2021
This is version 27 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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