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Protein

Alanine racemase

Gene

AMD02_16720

Organism
Bacillus okuhidensis
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotationSAAS annotation

Pathwayi: D-alanine biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes D-alanine from L-alanine.UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Alanine racemase (AMD02_16720)
This subpathway is part of the pathway D-alanine biosynthesis, which is itself part of Amino-acid biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-alanine from L-alanine, the pathway D-alanine biosynthesis and in Amino-acid biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei40Proton acceptor; specific for D-alanineUniRule annotation1
Binding sitei137SubstrateUniRule annotation1
Active sitei269Proton acceptor; specific for L-alanineUniRule annotation1
Binding sitei318Substrate; via amide nitrogenUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomeraseUniRule annotationSAAS annotation
LigandPyridoxal phosphateUniRule annotationSAAS annotation

Enzyme and pathway databases

UniPathwayiUPA00042; UER00497

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
ORF Names:AMD02_16720Imported
OrganismiBacillus okuhidensisImported
Taxonomic identifieri136160 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000037240 Componenti: Unassembled WGS sequence

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei40N6-(pyridoxal phosphate)lysineUniRule annotation1

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini248 – 375Ala_racemase_CInterPro annotationAdd BLAST128

Sequence similaritiesi

Belongs to the alanine racemase family.UniRule annotationSAAS annotation

Family and domain databases

Gene3Di2.40.37.10, 2 hits
3.20.20.10, 1 hit
HAMAPiMF_01201 Ala_racemase, 1 hit
InterProiView protein in InterPro
IPR000821 Ala_racemase
IPR009006 Ala_racemase/Decarboxylase_C
IPR011079 Ala_racemase_C
IPR001608 Ala_racemase_N
IPR020622 Ala_racemase_pyridoxalP-BS
IPR029066 PLP-binding_barrel
PfamiView protein in Pfam
PF00842 Ala_racemase_C, 1 hit
PF01168 Ala_racemase_N, 1 hit
PRINTSiPR00992 ALARACEMASE
SMARTiView protein in SMART
SM01005 Ala_racemase_C, 1 hit
SUPFAMiSSF50621 SSF50621, 1 hit
SSF51419 SSF51419, 1 hit
TIGRFAMsiTIGR00492 alr, 1 hit
PROSITEiView protein in PROSITE
PS00395 ALANINE_RACEMASE, 1 hit

Sequencei

Sequence statusi: Complete.

A0A0M0KDV3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEHFYRDTWV EVDLDAIEQN VTNALRLYKD REMNLMAVVK ANGYGHGAVE
60 70 80 90 100
VSQAALRAGA SYLSVAFLDE ALALRKAGID APILVMGLVD AEHVQLAIKH
110 120 130 140 150
RITLTVYQLD WLEQAISRLH TRDKLAIHLK LDTGMGRIGL RREEDIRSCM
160 170 180 190 200
DFIASHECFE LEGVFTHFAT ADEKDLTYFK KQCQRFNQWL EYIREWQLPI
210 220 230 240 250
RYVHCGNSAA GLRFPEKNFN MFRFGIAMYG LTPSPEITDE LPFPLKQAFS
260 270 280 290 300
LKSRLSNVKK LPKGEGISYG ATYVTEGAEW IGTLPIGYAD GWIRHHSNAG
310 320 330 340 350
GHVLIDGKRA PFVGLICMDQ CMIRLPKKHS IGDTVTLIGE SDGKQITMDE
360 370 380
VAKRLNTINY EIPCVISWRV PRIYFRDGQI ISVKNNLL
Length:388
Mass (Da):44,037
Last modified:November 11, 2015 - v1
Checksum:i8DBF8D4BD508C878
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LILD01000003 Genomic DNA Translation: KOO37016.1
RefSeqiWP_053432221.1, NZ_LILD01000003.1

Genome annotation databases

EnsemblBacteriaiKOO37016; KOO37016; AMD02_16720
PATRICifig|136160.3.peg.4303

Similar proteinsi

Entry informationi

Entry nameiA0A0M0KDV3_9BACI
AccessioniPrimary (citable) accession number: A0A0M0KDV3
Entry historyiIntegrated into UniProtKB/TrEMBL: November 11, 2015
Last sequence update: November 11, 2015
Last modified: February 28, 2018
This is version 16 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

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