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Entry version 20 (11 Dec 2019)
Sequence version 1 (11 Nov 2015)
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Protein
Submitted name:

YPP1p Cargo-transport protein involved in endocytosis

Gene

KO01_01742

Organism
Saccharomyces sp. 'boulardii'
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
YPP1p Cargo-transport protein involved in endocytosisImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:KO01_01742Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSaccharomyces sp. 'boulardii'Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri252598 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomycesunclassified Saccharomyces
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000037662 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome VII

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei962 – 980HelicalSequence analysisAdd BLAST19
Transmembranei1012 – 1032HelicalSequence analysisAdd BLAST21
Transmembranei1067 – 1086HelicalSequence analysisAdd BLAST20
Transmembranei1098 – 1115HelicalSequence analysisAdd BLAST18
Transmembranei1433 – 1453HelicalSequence analysisAdd BLAST21
Transmembranei1465 – 1486HelicalSequence analysisAdd BLAST22
Transmembranei1498 – 1517HelicalSequence analysisAdd BLAST20
Transmembranei1529 – 1551HelicalSequence analysisAdd BLAST23

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1151 – 1205MIRInterPro annotationAdd BLAST55
Domaini1220 – 1278MIRInterPro annotationAdd BLAST59
Domaini1293 – 1351MIRInterPro annotationAdd BLAST59

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili66 – 86Sequence analysisAdd BLAST21
Coiled coili468 – 488Sequence analysisAdd BLAST21
Coiled coili651 – 671Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis, RepeatSAAS annotation, Transmembrane, Transmembrane helixSequence analysis

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.40.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR027005 GlyclTrfase_39-like
IPR003342 Glyco_trans_39/83
IPR036300 MIR_dom_sf
IPR016093 MIR_motif
IPR032421 PMT_4TMC
IPR011990 TPR-like_helical_dom_sf

The PANTHER Classification System

More...
PANTHERi
PTHR10050 PTHR10050, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02815 MIR, 1 hit
PF02366 PMT, 1 hit
PF16192 PMT_4TMC, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00472 MIR, 3 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48452 SSF48452, 1 hit
SSF82109 SSF82109, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50919 MIR, 3 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A0L8VPV3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPNSNVRIPP TVPSKIIDVV DQALRARLLG GSTFNSGFDS LDSVLNLQFR
60 70 80 90 100
LHYHVIGSNG PAKPVCDVLL KESQNLEKNM SMMEELNDYP EITKLVEKIL
110 120 130 140 150
FNCLAILFFH RGQFQESQRC LLHSLKIHNN TASQRTALME QYDRYLIVEN
160 170 180 190 200
LYYRGLVSQD INIMQNVFYK ELLAHVDTVP PESNGLLFEY ISLIVAKLRF
210 220 230 240 250
NQIQDLAENF KTTVENPFIL FLYMIKKFQS PLKKHIDNDD LYLKFGQNVL
260 270 280 290 300
LKVKFPTASE TNDEALEHFN VFLQYYFKFT HIKKIKVNPS WYNFIISSME
310 320 330 340 350
KTFQSIEVSK TAMFLFQNLS DNSNDEIKKK TFKRESILNF VNFVKYNDKY
360 370 380 390 400
YQLHDNSHHD IISFIDAYSF ILQNSSKTDS IENVFDYDNT VSTFATSLNS
410 420 430 440 450
FYKEYNLPLM SQSESLDWLE NSTRCVYPGN ISKVLTNAWS TLYEIRKCQL
460 470 480 490 500
DFLVSNNLTS YLCNAMMLST KEKDNADVEE QEEGEEEKAL RELQFKYSYT
510 520 530 540 550
LAQQRHIETA IKTLESLILS KNPNYYKAWH LLALCRSVQE DKEMSYKIVC
560 570 580 590 600
SVLEAMNESL QNNTLLLNDR WQFIHLKLTQ LALIEEIFGT LEALETLPEV
610 620 630 640 650
FELYATLFPD SQPKLNSMGP KYSQTKEYLL QMVWIFAANM YMRTKDNDED
660 670 680 690 700
AKAAIKEASN VESKFKNLNC NIANGYLSII KDEPGVALKE FETVLYYDEN
710 720 730 740 750
NLDALVGFAE LIFPEELGVE ETNLERYYTL SLDKKPGKRA KLTFVNDTDR
760 770 780 790 800
SAAYARLKFL LECAILESIE AYYSPEVWWY LSLIYEKYQD DEYKNSLLKC
810 820 830 840 850
IKYQELNPIR SLSKAKGTGF SSIDTEDENL RERYVNQPKA NASDIQDEQL
860 870 880 890 900
DCFEQLEEKH RTKKNEEYTA LKILRDVIGP LLLTITSFYL RFQHIDQNNY
910 920 930 940 950
VVWDEAHFGK FGSYYIKHEY YHDVHPPLGK MLIALSEWMA GFDGQFDFSS
960 970 980 990 1000
NNAYPENVNF KLMRQFNATF GALCTPVAFF TAKWMGFNYF TVYLIATMVT
1010 1020 1030 1040 1050
LEHSYIVLSK FILLDSMLLF FSMTTFACMI KLYTLRKQQM TKKWSLWMLL
1060 1070 1080 1090 1100
TGLSIGCVCS VKWVGLFITV VVGLYTCIEL FLLYCGKELP RIKYYKHWLI
1110 1120 1130 1140 1150
RIINLIVIPF LIYLYCFKIH FVLLYKSGTG DSTTNTLFQI NLEGTQIEAG
1160 1170 1180 1190 1200
PRDVAFGSEL TIRSHGLSPN LLHSHIQVYP EGSGQRQITG YGFADSNNVW
1210 1220 1230 1240 1250
KFEFSRSSGL ELDQNGTLNG KIIPITDGVE VRLSHKNTGS NLHSHDVPSH
1260 1270 1280 1290 1300
VSRGNYEVSG YGSQSVGDEK DDWIVEIVKQ MDSPNPVYSN ENSTILHPVS
1310 1320 1330 1340 1350
TFFRLRHKVL GCYLASTGLT YPAWGFKQAE IVCKDSWSRR DKSTWWNVED
1360 1370 1380 1390 1400
HWNHNLETAE DYVPPKSNFW TDFILTNFAM ASSNNALVPD EDKYDSLSSD
1410 1420 1430 1440 1450
AWEWPTLHKG LRMCSWAGYI TRYYLMGSPF NTWISTVSLI IFPFIILFIL
1460 1470 1480 1490 1500
YRWRRQTLYL SDDQIWQITI QGIFPFISWM THYLPFAMMG RVTYVHHYVP
1510 1520 1530 1540 1550
ALYFAMLVFG FVLDFTLTRV HWMVKYPIYL SLFGGCIYIY NLFAPICQGM
1560 1570
HGDKAEYLPL QWLSTWDIAP
Length:1,570
Mass (Da):182,461
Last modified:November 11, 2015 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i4543D9744A2204BF
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
LIIL01000019 Genomic DNA Translation: KOH50499.1

Genome annotation databases

Ensembl fungal genome annotation project

More...
EnsemblFungii
KOH50499; KOH50499; KO01_01742
KQC43702; KQC43702; AB282_01958

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LIIL01000019 Genomic DNA Translation: KOH50499.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsemblFungiiKOH50499; KOH50499; KO01_01742
KQC43702; KQC43702; AB282_01958

Family and domain databases

Gene3Di1.25.40.10, 1 hit
InterProiView protein in InterPro
IPR027005 GlyclTrfase_39-like
IPR003342 Glyco_trans_39/83
IPR036300 MIR_dom_sf
IPR016093 MIR_motif
IPR032421 PMT_4TMC
IPR011990 TPR-like_helical_dom_sf
PANTHERiPTHR10050 PTHR10050, 1 hit
PfamiView protein in Pfam
PF02815 MIR, 1 hit
PF02366 PMT, 1 hit
PF16192 PMT_4TMC, 1 hit
SMARTiView protein in SMART
SM00472 MIR, 3 hits
SUPFAMiSSF48452 SSF48452, 1 hit
SSF82109 SSF82109, 1 hit
PROSITEiView protein in PROSITE
PS50919 MIR, 3 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A0L8VPV3_9SACH
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A0L8VPV3
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 11, 2015
Last sequence update: November 11, 2015
Last modified: December 11, 2019
This is version 20 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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