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Protein

Aconitate hydratase, mitochondrial

Gene

KO01_02596

Organism
Saccharomyces sp. 'boulardii'
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Cofactori

[4Fe-4S] clusterUniRule annotationNote: Binds 1 [4Fe-4S] cluster per subunit.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyaseUniRule annotation
LigandIron, Iron-sulfurUniRule annotation, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Aconitate hydratase, mitochondrialUniRule annotation (EC:4.2.1.-UniRule annotation)
Short name:
AconitaseUniRule annotation
Gene namesi
ORF Names:KO01_02596Imported
OrganismiSaccharomyces sp. 'boulardii'Imported
Taxonomic identifieri252598 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000037662 Componenti: Chromosome X

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

MitochondrionUniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini58 – 505AconitaseInterPro annotationAdd BLAST448
Domaini586 – 713Aconitase_CInterPro annotationAdd BLAST128

Sequence similaritiesi

Belongs to the aconitase/IPM isomerase family.UniRule annotation

Keywords - Domaini

Transit peptideUniRule annotation

Family and domain databases

Gene3Di3.20.19.10, 1 hit
3.30.499.10, 2 hits
3.40.1060.10, 1 hit
InterProiView protein in InterPro
IPR015931 Acnase/IPM_dHydase_lsu_aba_1/3
IPR001030 Acoase/IPM_deHydtase_lsu_aba
IPR015928 Aconitase/3IPM_dehydase_swvl
IPR018136 Aconitase_4Fe-4S_BS
IPR036008 Aconitase_4Fe-4S_dom
IPR015932 Aconitase_dom2
IPR006248 Aconitase_mito-like
IPR000573 AconitaseA/IPMdHydase_ssu_swvl
PfamiView protein in Pfam
PF00330 Aconitase, 1 hit
PF00694 Aconitase_C, 1 hit
PRINTSiPR00415 ACONITASE
SUPFAMiSSF53732 SSF53732, 1 hit
TIGRFAMsiTIGR01340 aconitase_mito, 1 hit
PROSITEiView protein in PROSITE
PS00450 ACONITASE_1, 1 hit
PS01244 ACONITASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

A0A0L8VNC4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLSSANRFYI KRHLATHANM FPSVSKNFQT KVPPYAKLLT NLDKIKQITN
60 70 80 90 100
NAPLTLAEKI LYSHLCDPEE SITSSDLSTI RGNKYLKLNP DRVAMQDASA
110 120 130 140 150
QMALLQFMTT GLNQTSVPAS IHCDHLIVGK DGETKDLPSS IATNQEVFDF
160 170 180 190 200
LESCAKRYGI QFWGPGSGII HQIVLENFSA PGLMMLGTDS HTPNAGGLGA
210 220 230 240 250
IAIGVGGADA VDALTGTPWE LKAPKILGVK LTGKLNGWST PKDVITKLAG
260 270 280 290 300
LLTVRGGTGY IVEYFGEGVS TLSCTGMATI CNMGAEIGAT TSTFPYQEAH
310 320 330 340 350
KRYLQATNRA EVAEAADVAL NKFNFLRADK DAQYDKVIEI DLSAIEPHVN
360 370 380 390 400
GPFTPDLSTP ISQYAEKSLK ENWPQKVSAG LIGSCTNSSY QDMSRVVDLV
410 420 430 440 450
RQASKAGLKP RIPFFVTPGS EQIRATLERD GIIDIFQENG AKVLANACGP
460 470 480 490 500
CIGQWDREDV SKTSKETNTI FTSFNRNFRA RNDGNRNTMN FLTSPEIVTA
510 520 530 540 550
MSYSGDAQFN PLTDSIKLPN GKDFKFQPPK GDELPKRGFE HGRDKFYPEM
560 570 580 590 600
DPKPDSSVEI KVDPNSDRLQ LLEPFKPWNG KELKTNVLLK VEGKCTTDHI
610 620 630 640 650
SAAGVWLKYK GHLENISYNT LIGAQNKETG EVNKAYDLDG TEYDIPGLMM
660 670 680 690 700
KWKSDGRPWT VIAEHNYGEG SAREHAALSP RFLGGEILLV KSFARIHETN
710 720 730 740 750
LKKQGVLPLT FANESDYDKI SSGDVLETLN LVDMVAKDGN NGGEIDVKIT
760 770 780
KPNGESFTIK AKHTMSKDQI DFFKAGSAIN YIGNIRRNE
Length:789
Mass (Da):86,571
Last modified:November 11, 2015 - v1
Checksum:i4372F565273CA834
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LIIL01000022 Genomic DNA Translation: KOH49642.1

Genome annotation databases

EnsemblFungiiKOH49642; KOH49642; KO01_02596

Similar proteinsi

Entry informationi

Entry nameiA0A0L8VNC4_9SACH
AccessioniPrimary (citable) accession number: A0A0L8VNC4
Entry historyiIntegrated into UniProtKB/TrEMBL: November 11, 2015
Last sequence update: November 11, 2015
Last modified: February 28, 2018
This is version 18 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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