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UniProtKB - A0A0L8HP93 (A0A0L8HP93_OCTBM)

Entry version 17 (07 Oct 2020)
Sequence version 1 (11 Nov 2015)
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Protein

ALMS_motif domain-containing protein

Gene

OCBIM_22010986mg

Organism
Octopus bimaculoides (California two-spotted octopus)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
ALMS_motif domain-containing proteinInterPro annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:OCBIM_22010986mgImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiOctopus bimaculoides (California two-spotted octopus)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri37653 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Spiralia › Lophotrochozoa › Mollusca › Cephalopoda › Coleoidea › Octopodiformes › Octopoda › Incirrata › Octopodidae › Octopus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000053454 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cytoplasm, CytoskeletonARBA annotation

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini875 – 1001ALMS_motifInterPro annotationAdd BLAST127

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 228DisorderedSequence analysisAdd BLAST228
Regioni255 – 288DisorderedSequence analysisAdd BLAST34
Regioni590 – 668DisorderedSequence analysisAdd BLAST79
Regioni825 – 848DisorderedSequence analysisAdd BLAST24

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili416 – 444Sequence analysisAdd BLAST29
Coiled coili495 – 515Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1 – 39PolarSequence analysisAdd BLAST39
Compositional biasi57 – 80PolarSequence analysisAdd BLAST24
Compositional biasi113 – 131PolarSequence analysisAdd BLAST19
Compositional biasi132 – 182PolyampholyteSequence analysisAdd BLAST51
Compositional biasi183 – 204PolarSequence analysisAdd BLAST22
Compositional biasi205 – 228PolyampholyteSequence analysisAdd BLAST24
Compositional biasi607 – 640PolarSequence analysisAdd BLAST34
Compositional biasi641 – 668PolyampholyteSequence analysisAdd BLAST28
Compositional biasi833 – 848PolyampholyteSequence analysisAdd BLAST16

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

Database of Orthologous Groups

More...OrthoDBi		824330at2759

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR029299, ALMS_motif

Pfam protein domain database

More...Pfami		View protein in Pfam
PF15309, ALMS_motif, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A0L8HP93-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MYHSSSCDPR ETSSQSKLNP SPSGSDSSTL SQKTWTLRPY KPPGSQDWYY 
        60         70         80         90        100
TGASGFPPFS VSDSGTITTA TTTTMESGDT GSDDAIGPHI QKEFLGSRPD 
       110        120        130        140        150
GPSIPGIYSR APGKKKSNTT DNPLLSTIQE RSTLNDKDKM KTKSKQEIKE 
       160        170        180        190        200
STSSYRETRR NWVDSQDTYS RFDSKKLSES NYPNEVHHTA SKVDYVSSDQ 
       210        220        230        240        250
LESFRKNSSS KEQFDPTKSK GCQRHRNGRH EGLDLQGVKH KETTVVHGIQ 
       260        270        280        290        300
RDANSYKQSS FESVTTVETP SDFSTDPESA TSSSKTIESS HFVSHDSDAL 
       310        320        330        340        350
VLALAKNEET GMQQAWGDLT MTGHNLPNGE QVIFRSDMCV TYKPTEPTKS 
       360        370        380        390        400
QLSRQDSYSQ RISRSAQELD LLWQKFKQQA APPSPENSLD SSRLEQIQHL 
       410        420        430        440        450
VKNPTQALVR RSINLLEEKR QQQAERAEQN LELQKQSLLK QKLREVDDST 
       460        470        480        490        500
QSSVTSGAES VYSLSENVET MSGSYCAEER ENANIVYSGS FDPMIAKLRK 
       510        520        530        540        550
KIEKQRQKCE LMKKRDKASE EKLHKLTSIL VTRQMNDLIL ASEMNSLSTT 
       560        570        580        590        600
STATCMTNST MESTEQSSSK KIPVYSQCCG KCRACNERLT SKPRHSSRLK 
       610        620        630        640        650
HPKRPYRVTS TNFTSRNTAR STESKFGTSS LTVDHIPSKH NVKGQSTERQ 
       660        670        680        690        700
PKGDDRHFME APTFSEVSDK RKPIRKVLPK QDATTMVPSP LTVCDANLNY 
       710        720        730        740        750
SASQAEMSKI SVAVQTSPNL ENNTKYQTTA ECTTSYSKTS IKPTSPGEIQ 
       760        770        780        790        800
IAPKSCPAED LKVIPVPFMW TPKKQKSKTK TLHPPDCHYS NQQRKLAEKE 
       810        820        830        840        850
KIGETWFVSL SETNISRTDH NCRASGTSNC KRSQKHIRSD SAGVRKVSKH 
       860        870        880        890        900
KEQIPVIFNN SFDSHSFSSR SNKPRITLQE AFQNYMPNWI SRSRERQKRI 
       910        920        930        940        950
LLAAQERRYQ MQMEMERNKI FQNKKPSTTA SENDPVCENL YKPKKRAFSK 
       960        970        980        990       1000
QEMKELNWKL YRNLPEVISQ KVEQTRKIQY KYNKTKSRVF SMKVQKNILN 

KVSKKI
Length:1,006
Mass (Da):113,974
Last modified:November 11, 2015 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB22EB58AAF4E1D3B
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
KQ417731 Genomic DNA Translation: KOF90545.1

NCBI Reference Sequences

More...RefSeqi		XP_014770975.1, XM_014915489.1

Genome annotation databases

Ensembl metazoan genome annotation project

More...EnsemblMetazoai		Ocbimv22010986m; Ocbimv22010986m.p; Ocbimv22010986m.g

Database of genes from NCBI RefSeq genomes

More...GeneIDi		106869671

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		obi:106869671

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KQ417731 Genomic DNA Translation: KOF90545.1
RefSeqiXP_014770975.1, XM_014915489.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Genome annotation databases

EnsemblMetazoaiOcbimv22010986m; Ocbimv22010986m.p; Ocbimv22010986m.g
GeneIDi106869671
KEGGiobi:106869671

Phylogenomic databases

OrthoDBi824330at2759

Family and domain databases

InterProiView protein in InterPro
IPR029299, ALMS_motif
PfamiView protein in Pfam
PF15309, ALMS_motif, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A0L8HP93_OCTBM
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A0L8HP93
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 11, 2015
Last sequence update: November 11, 2015
Last modified: October 7, 2020
This is version 17 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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