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Entry version 33 (12 Aug 2020)
Sequence version 1 (11 Nov 2015)
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Protein
Submitted name:

FiLamiN (Actin binding protein) homolog

Gene

fln-2

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
FiLamiN (Actin binding protein) homologImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:fln-2Imported
ORF Names:C23F12.1Imported, CELE_C23F12.1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCaenorhabditis elegansImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6239 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditinaRhabditomorphaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001940 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

WormBase

More...
WormBasei
C23F12.1n ; CE50505 ; WBGene00016006 ; fln-2

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
A0A0K3AYI1

PeptideAtlas

More...
PeptideAtlasi
A0A0K3AYI1

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
A0A0K3AYI1, baseline and differential

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
A0A0K3AYI1

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati1 – 91FilaminPROSITE-ProRule annotationAdd BLAST91
Repeati109 – 178FilaminPROSITE-ProRule annotationAdd BLAST70
Repeati879 – 963FilaminPROSITE-ProRule annotationAdd BLAST85
Repeati961 – 1056FilaminPROSITE-ProRule annotationAdd BLAST96
Repeati1135 – 1209FilaminPROSITE-ProRule annotationAdd BLAST75
Repeati1219 – 1296FilaminPROSITE-ProRule annotationAdd BLAST78
Repeati1294 – 1389FilaminPROSITE-ProRule annotationAdd BLAST96
Repeati1403 – 1478FilaminPROSITE-ProRule annotationAdd BLAST76
Repeati1541 – 1623FilaminPROSITE-ProRule annotationAdd BLAST83
Repeati1634 – 1706FilaminPROSITE-ProRule annotationAdd BLAST73
Repeati1711 – 1797FilaminPROSITE-ProRule annotationAdd BLAST87
Repeati1807 – 1886FilaminPROSITE-ProRule annotationAdd BLAST80
Repeati1884 – 1978FilaminPROSITE-ProRule annotationAdd BLAST95
Repeati1976 – 2069FilaminPROSITE-ProRule annotationAdd BLAST94
Repeati2067 – 2161FilaminPROSITE-ProRule annotationAdd BLAST95
Repeati2159 – 2254FilaminPROSITE-ProRule annotationAdd BLAST96
Repeati2295 – 2389FilaminPROSITE-ProRule annotationAdd BLAST95
Repeati2391 – 2484FilaminPROSITE-ProRule annotationAdd BLAST94
Repeati2485 – 2581FilaminPROSITE-ProRule annotationAdd BLAST97

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni216 – 280DisorderedSequence analysisAdd BLAST65
Regioni293 – 358DisorderedSequence analysisAdd BLAST66
Regioni429 – 451DisorderedSequence analysisAdd BLAST23
Regioni469 – 498DisorderedSequence analysisAdd BLAST30
Regioni553 – 573DisorderedSequence analysisAdd BLAST21
Regioni716 – 776DisorderedSequence analysisAdd BLAST61
Regioni820 – 847DisorderedSequence analysisAdd BLAST28
Regioni1072 – 1133DisorderedSequence analysisAdd BLAST62
Regioni2266 – 2296DisorderedSequence analysisAdd BLAST31
Regioni2630 – 2656DisorderedSequence analysisAdd BLAST27

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi219 – 236PolarSequence analysisAdd BLAST18
Compositional biasi237 – 257PolyampholyteSequence analysisAdd BLAST21
Compositional biasi259 – 280PolarSequence analysisAdd BLAST22
Compositional biasi429 – 449PolyampholyteSequence analysisAdd BLAST21
Compositional biasi483 – 498PolarSequence analysisAdd BLAST16
Compositional biasi731 – 749PolyampholyteSequence analysisAdd BLAST19
Compositional biasi1083 – 1113PolyampholyteSequence analysisAdd BLAST31
Compositional biasi2632 – 2646Pro-richSequence analysisAdd BLAST15

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.10, 19 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR017868, Filamin/ABP280_repeat-like
IPR001298, Filamin/ABP280_rpt
IPR013783, Ig-like_fold
IPR014756, Ig_E-set

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00630, Filamin, 9 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00557, IG_FLMN, 18 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF81296, SSF81296, 19 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50194, FILAMIN_REPEAT, 19 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 21 potential isoforms that are computationally mapped.Show allAlign All

A0A0K3AYI1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSYYSELSGP GLVRAPVNRT AQFDITGEGL ELSDIQAKIS GPDNREYPIR
60 70 80 90 100
IIPRSSGKYT AEYEIEQVGE HHLTVWIAGR KVDGSPLSVA GYATEKVRLE
110 120 130 140 150
PLGGGVPKQP VQFYVDAVEA GKGQLEISVN QGKVPNNVQM QGAGRCLVTF
160 170 180 190 200
IPQHAGTYVI DVTFNGEQVH GCPIKVEILP KQVGQQIHAN LTPTAVSTAI
210 220 230 240 250
SAGGTSLISG AFRETARSPL SARSPTSPTL LQHARQRSEE TMLRSPQLLR
260 270 280 290 300
ESRKADKPWQ SSYAPSSSRN AFSQSPHRDW SASTVYDRVY NSNSDVERTL
310 320 330 340 350
SPSDPSRNRN IRETTTVIHR TPSPTGLRST QITETITRTT HRSPSPPRGV
360 370 380 390 400
SNTSFGSVRT QEFAERIARS PSPTGYEREF VEKRTTYRSP SPARTSSVAH
410 420 430 440 450
SHISEVPLSP IQGMDTPFDH HERVKKVERM DPLADEEERE QRRNQLERDS
460 470 480 490 500
KNTLGYTVAQ YGDGEKRYFG DTLEKKDRPP SAGYYSSVQQ RSTSPEYSTV
510 520 530 540 550
YERYDRKSEK PDLPPRVEGH VSASYKGYEP VYSEVTTTRT TTTTEYENID
560 570 580 590 600
KKPNVPKKRA TTPEGHVEPV NDNEEKDRQA FLRTQSEKVF EPVDAPLRRS
610 620 630 640 650
DEKESIYDLP PQERLHKYPE EPTIALGEKA NTSAIAAYTK GRQDDIDEVS
660 670 680 690 700
RNASFPSAPT INYNERSDEV SNYNRTKEDH YGVVGEYPTA PKIAYSDSKE
710 720 730 740 750
AVIREHYAQA KEDPYATVGE CPPAPEISLR SDKLNETKNE YRRTTDSDQQ
760 770 780 790 800
DGKAGPPPPV IEISKAEQAR RTEEYLRVKS EDDKILAKHG FTRKPEPSIE
810 820 830 840 850
IQEPVTEQIR DDVVETAIAP EVPLRPVEEL PHSPAPSSRS TPATTPKLSA
860 870 880 890 900
KFRKDGKEGK PFDFGKSKFV CKHDVIKRGK EVEVKLEGIK LGKEDQLRVV
910 920 930 940 950
VLPPANKAIP GANGGPPTEV DTKVKKSSSK YEISFKPTEV GTHKVFAYVN
960 970 980 990 1000
DMQHPLSPFA VRVYDASEII VGEIPNQSNL NDTVEFTVDA GRAGFGNLEM
1010 1020 1030 1040 1050
AIKDADGVII PSHVAQLESG SAKFLVTFTP ATKGPHTVNI TFNKEVLKNS
1060 1070 1080 1090 1100
PFEVNIVDAP LPAPVVLEPA SGASAVASPS LSKKELKEQE KEKKREEKER
1110 1120 1130 1140 1150
AKREKEERAT LKKEKKSKSH RFPAKTTVSK IPSLSRVGQP SSLVVEVSGH
1160 1170 1180 1190 1200
DQLEIRVLDS KKSEIGTDIV EIEPGHMQIN FTPAQVGDHE IDVRYGGVPV
1210 1220 1230 1240 1250
TGSPFTCRAY DPAKIKVGAI PKGLLDKPVY FTVDASEAGV GNLEVAVCEG
1260 1270 1280 1290 1300
RVPSMAHALG HHKYDISFVP KEDVDHTITV RFNNEPVPGS PFLCQLVATA
1310 1320 1330 1340 1350
QATATGAGLE RIPVDEETEI QILTDEIDSA PEARVRDPQG NDLPVNVTRS
1360 1370 1380 1390 1400
RENETLHIAT YVPKCVGNHL IDIFLQGEPI AGSPFTAKAY DARKTVLVPP
1410 1420 1430 1440 1450
ANAVVGKPAT FVIDAARSGA GNMEIIVSVD NRNVPNFVQA EGQARFKVSF
1460 1470 1480 1490 1500
TPQDAKDHTI SVKFNGISVP GSPLICSVSS AGSVPAAVVL PAAAVIGAET
1510 1520 1530 1540 1550
AVAARERIKH TPQHSSEQIK QTTTTVLQKT PEIRETVEKT GLARELNSAQ
1560 1570 1580 1590 1600
IGQKKGFTID NINKSSDCNV IITAPDGSMV PVSIQKSSTS AYAEFTPTIT
1610 1620 1630 1640 1650
GEHLVEIYLD HEIIDEFVIK IKDERHILPP VCLAGQKYSF DVNSDDKNKV
1660 1670 1680 1690 1700
RVTIREPSGR MLPVQMEDLP DGGVRVSCRF KEVGIHSIDV FVDDQPIGER
1710 1720 1730 1740 1750
KMQTVIDPLN GAQLVSEPKR EIVGEQTELK ILIDSGVESQ VEVIIEGPDR
1760 1770 1780 1790 1800
EDNEVFVKKV SETLWSAVWT PKVEGEHELS ILVAGEQIPG SPFPIHVLDP
1810 1820 1830 1840 1850
SAVRVIGLKN APVGVEQQFS VDYTNSGASI ASVEVRHGDQ TIPITVKKMK
1860 1870 1880 1890 1900
PGQLLCTFTP FVDGPHQVEV IIDGVPLSDG PYEVFISHLG TVRASGDALR
1910 1920 1930 1940 1950
KAQRARTARF EVINVEQNRG ELDVMVSDPK GGPLPVRCYK QQDDSYWVEF
1960 1970 1980 1990 2000
TPEHLGTHTI EVTFGDVPVP GSPFKTEVID PKNVEIRGLS DQVLLRHATT
2010 2020 2030 2040 2050
INVDRRNAGN GELQVEITDP TGSPLRTEML KSPGGEDRIT FLPNQTGPHK
2060 2070 2080 2090 2100
INVKVAGFQI PGYPQTILVS EQEKPAVYGA AVDQSIKIGE PASLIFDPKK
2110 2120 2130 2140 2150
TNGGLKIHAT GPDGQKVHHN VMRRPNGTSE VVFYPEETGT YNVSIDFNNR
2160 2170 2180 2190 2200
PITGSPFTVN VVDPTKVIVN DLDMDRDGTL LLRLGHSNSF DVDATAAGPG
2210 2220 2230 2240 2250
KLRAEVRDAD SSLIGNGPVV EDMGQGKYRV RFNPDQPGKY SIYLYWNELP
2260 2270 2280 2290 2300
VESAFPVRAR SSAEDLPTTS RAVREPIPPP VTTTYHTREK SSGSNADDEI
2310 2320 2330 2340 2350
SRIMVRGDGL HRAVLKEHNE FIIDGSDINK EGRITATLLG SKADIPVRIQ
2360 2370 2380 2390 2400
QLGHNVYKAT YTPLTGGTYE LHILWNGKHV KGSPFAVSAD TSAHLADLID
2410 2420 2430 2440 2450
VDASTLKIGI INENIKTLID TRRAGSGQLS ALCMGPNKPA YCELYDHRDG
2460 2470 2480 2490 2500
TYALCVRPAE IGKHTLVIKY DDEHVKGSPF VVHVSLPPDP SKVRVYGPGV
2510 2520 2530 2540 2550
EHGILSLFKS NFVVETRGAG AGQLTVRVRG PKGAFNVEMQ REKKNERTIH
2560 2570 2580 2590 2600
CKYEPKEPGD YQVEVKWHGE HVPGSPFLVM IVDTEKELSR YLRGEAPSPT
2610 2620 2630 2640 2650
PATPFIPPGW VAPPQMYPMQ PGQQRFLPPP GHFGPMGVPS PYGSVPPPTK

HKGRNH
Length:2,656
Mass (Da):291,626
Last modified:November 11, 2015 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iBF0BADBC98F3584F
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 21 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
D0VWL6D0VWL6_CAEEL
FiLamiN (Actin binding protein) hom...
fln-2 C23F12.1, CELE_C23F12.1
3,611Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D0VWL8D0VWL8_CAEEL
FiLamiN (Actin binding protein) hom...
fln-2 C23F12.1, CELE_C23F12.1
2,391Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D0VWL7D0VWL7_CAEEL
FiLamiN (Actin binding protein) hom...
fln-2 C23F12.1, CELE_C23F12.1
2,776Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0K3AT80A0A0K3AT80_CAEEL
FiLamiN (Actin binding protein) hom...
fln-2 C23F12.1, CELE_C23F12.1
2,864Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0K3AW96A0A0K3AW96_CAEEL
FiLamiN (Actin binding protein) hom...
fln-2 C23F12.1, CELE_C23F12.1
3,039Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0K3ASN4A0A0K3ASN4_CAEEL
FiLamiN (Actin binding protein) hom...
fln-2 C23F12.1, CELE_C23F12.1
2,720Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0K3ASN9A0A0K3ASN9_CAEEL
FiLamiN (Actin binding protein) hom...
fln-2 C23F12.1, CELE_C23F12.1
2,030Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0K3AT74A0A0K3AT74_CAEEL
FiLamiN (Actin binding protein) hom...
fln-2 C23F12.1, CELE_C23F12.1
3,226Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0K3AT86A0A0K3AT86_CAEEL
FiLamiN (Actin binding protein) hom...
fln-2 C23F12.1, CELE_C23F12.1
2,271Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0K3AVH5A0A0K3AVH5_CAEEL
FiLamiN (Actin binding protein) hom...
fln-2 C23F12.1, CELE_C23F12.1
2,243Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
There are more potential isoformsShow all

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BX284606 Genomic DNA Translation: CTQ87040.1

NCBI Reference Sequences

More...
RefSeqi
NP_001300329.1, NM_001313400.1

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
C23F12.1n.1; C23F12.1n.1; WBGene00016006

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
181168

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284606 Genomic DNA Translation: CTQ87040.1
RefSeqiNP_001300329.1, NM_001313400.1

3D structure databases

SMRiA0A0K3AYI1
ModBaseiSearch...

Proteomic databases

EPDiA0A0K3AYI1
PeptideAtlasiA0A0K3AYI1

Genome annotation databases

EnsemblMetazoaiC23F12.1n.1; C23F12.1n.1; WBGene00016006
GeneIDi181168

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
181168
WormBaseiC23F12.1n ; CE50505 ; WBGene00016006 ; fln-2

Gene expression databases

ExpressionAtlasiA0A0K3AYI1, baseline and differential

Family and domain databases

Gene3Di2.60.40.10, 19 hits
InterProiView protein in InterPro
IPR017868, Filamin/ABP280_repeat-like
IPR001298, Filamin/ABP280_rpt
IPR013783, Ig-like_fold
IPR014756, Ig_E-set
PfamiView protein in Pfam
PF00630, Filamin, 9 hits
SMARTiView protein in SMART
SM00557, IG_FLMN, 18 hits
SUPFAMiSSF81296, SSF81296, 19 hits
PROSITEiView protein in PROSITE
PS50194, FILAMIN_REPEAT, 19 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A0K3AYI1_CAEEL
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A0K3AYI1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 11, 2015
Last sequence update: November 11, 2015
Last modified: August 12, 2020
This is version 33 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
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