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Entry version 33 (12 Aug 2020)
Sequence version 1 (11 Nov 2015)
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Protein
Submitted name:

FiLamiN (Actin binding protein) homolog

Gene

fln-2

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
FiLamiN (Actin binding protein) homologImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:fln-2Imported
ORF Names:C23F12.1Imported, CELE_C23F12.1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCaenorhabditis elegansImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6239 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditinaRhabditomorphaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001940 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

WormBase

More...
WormBasei
C23F12.1h ; CE50504 ; WBGene00016006 ; fln-2

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PeptideAtlas

More...
PeptideAtlasi
A0A0K3AW96

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
A0A0K3AW96, baseline and differential

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
A0A0K3AW96

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati16 – 97FilaminPROSITE-ProRule annotationAdd BLAST82
Repeati107 – 187FilaminPROSITE-ProRule annotationAdd BLAST81
Repeati185 – 279FilaminPROSITE-ProRule annotationAdd BLAST95
Repeati279 – 370FilaminPROSITE-ProRule annotationAdd BLAST92
Repeati392 – 474FilaminPROSITE-ProRule annotationAdd BLAST83
Repeati492 – 561FilaminPROSITE-ProRule annotationAdd BLAST70
Repeati1262 – 1346FilaminPROSITE-ProRule annotationAdd BLAST85
Repeati1344 – 1439FilaminPROSITE-ProRule annotationAdd BLAST96
Repeati1518 – 1592FilaminPROSITE-ProRule annotationAdd BLAST75
Repeati1602 – 1679FilaminPROSITE-ProRule annotationAdd BLAST78
Repeati1677 – 1772FilaminPROSITE-ProRule annotationAdd BLAST96
Repeati1786 – 1861FilaminPROSITE-ProRule annotationAdd BLAST76
Repeati1924 – 2006FilaminPROSITE-ProRule annotationAdd BLAST83
Repeati2017 – 2089FilaminPROSITE-ProRule annotationAdd BLAST73
Repeati2094 – 2180FilaminPROSITE-ProRule annotationAdd BLAST87
Repeati2190 – 2269FilaminPROSITE-ProRule annotationAdd BLAST80
Repeati2267 – 2361FilaminPROSITE-ProRule annotationAdd BLAST95
Repeati2359 – 2452FilaminPROSITE-ProRule annotationAdd BLAST94
Repeati2450 – 2544FilaminPROSITE-ProRule annotationAdd BLAST95
Repeati2542 – 2637FilaminPROSITE-ProRule annotationAdd BLAST96
Repeati2678 – 2772FilaminPROSITE-ProRule annotationAdd BLAST95
Repeati2774 – 2867FilaminPROSITE-ProRule annotationAdd BLAST94
Repeati2868 – 2964FilaminPROSITE-ProRule annotationAdd BLAST97

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni599 – 663DisorderedSequence analysisAdd BLAST65
Regioni676 – 741DisorderedSequence analysisAdd BLAST66
Regioni812 – 834DisorderedSequence analysisAdd BLAST23
Regioni852 – 881DisorderedSequence analysisAdd BLAST30
Regioni936 – 956DisorderedSequence analysisAdd BLAST21
Regioni1099 – 1159DisorderedSequence analysisAdd BLAST61
Regioni1203 – 1230DisorderedSequence analysisAdd BLAST28
Regioni1455 – 1516DisorderedSequence analysisAdd BLAST62
Regioni2649 – 2679DisorderedSequence analysisAdd BLAST31
Regioni3013 – 3039DisorderedSequence analysisAdd BLAST27

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi602 – 619PolarSequence analysisAdd BLAST18
Compositional biasi620 – 640PolyampholyteSequence analysisAdd BLAST21
Compositional biasi642 – 663PolarSequence analysisAdd BLAST22
Compositional biasi812 – 832PolyampholyteSequence analysisAdd BLAST21
Compositional biasi866 – 881PolarSequence analysisAdd BLAST16
Compositional biasi1114 – 1132PolyampholyteSequence analysisAdd BLAST19
Compositional biasi1466 – 1496PolyampholyteSequence analysisAdd BLAST31
Compositional biasi3015 – 3029Pro-richSequence analysisAdd BLAST15

Phylogenomic databases

Database of Orthologous Groups

More...
OrthoDBi
35998at2759

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.10, 23 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR017868, Filamin/ABP280_repeat-like
IPR001298, Filamin/ABP280_rpt
IPR013783, Ig-like_fold
IPR014756, Ig_E-set

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00630, Filamin, 11 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00557, IG_FLMN, 22 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF81296, SSF81296, 23 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50194, FILAMIN_REPEAT, 23 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 21 potential isoforms that are computationally mapped.Show allAlign All

A0A0K3AW96-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPLTRSPDVG LVSFSGLTEP CSVGSIVEVV INAHGDAVSG SVYVEAVSPS
60 70 80 90 100
GNVHRCTVRH QDNSYMATFT PQEVGLWRIG ILYDGEHIRG SPFACQVFDS
110 120 130 140 150
GLVNVYGLDV GLVGQELNFS VNASQAGHGN LSVTVFRHGR EIPLSIEEQG
160 170 180 190 200
SSKVHQVSFT PDGAGQYKIH VLFNRMEIKG SPFILDIADA SSVSVYGENL
210 220 230 240 250
RSASVGKTAS FMVHAIGAEA KDISAHVTVP SGGKFPAKVV TLDDVTFQIE
260 270 280 290 300
WTPKEPGEHS VDVMLADQRV PDAPFACNVG APDLVHVRNM PRRIQPSKLH
310 320 330 340 350
TDHSFEIDAS AAGSGNLEIM INGGRVPCRV RELGSRQYMA IFTPTQSMTH
360 370 380 390 400
TIEMRFNGEH VSGSPWKLPV EDRGERRQEM ERTMSYYSEL SGPGLVRAPV
410 420 430 440 450
NRTAQFDITG EGLELSDIQA KISGPDNREY PIRIIPRSSG KYTAEYEIEQ
460 470 480 490 500
VGEHHLTVWI AGRKVDGSPL SVAGYATEKV RLEPLGGGVP KQPVQFYVDA
510 520 530 540 550
VEAGKGQLEI SVNQGKVPNN VQMQGAGRCL VTFIPQHAGT YVIDVTFNGE
560 570 580 590 600
QVHGCPIKVE ILPKQVGQQI HANLTPTAVS TAISAGGTSL ISGAFRETAR
610 620 630 640 650
SPLSARSPTS PTLLQHARQR SEETMLRSPQ LLRESRKADK PWQSSYAPSS
660 670 680 690 700
SRNAFSQSPH RDWSASTVYD RVYNSNSDVE RTLSPSDPSR NRNIRETTTV
710 720 730 740 750
IHRTPSPTGL RSTQITETIT RTTHRSPSPP RGVSNTSFGS VRTQEFAERI
760 770 780 790 800
ARSPSPTGYE REFVEKRTTY RSPSPARTSS VAHSHISEVP LSPIQGMDTP
810 820 830 840 850
FDHHERVKKV ERMDPLADEE EREQRRNQLE RDSKNTLGYT VAQYGDGEKR
860 870 880 890 900
YFGDTLEKKD RPPSAGYYSS VQQRSTSPEY STVYERYDRK SEKPDLPPRV
910 920 930 940 950
EGHVSASYKG YEPVYSEVTT TRTTTTTEYE NIDKKPNVPK KRATTPEGHV
960 970 980 990 1000
EPVNDNEEKD RQAFLRTQSE KVFEPVDAPL RRSDEKESIY DLPPQERLHK
1010 1020 1030 1040 1050
YPEEPTIALG EKANTSAIAA YTKGRQDDID EVSRNASFPS APTINYNERS
1060 1070 1080 1090 1100
DEVSNYNRTK EDHYGVVGEY PTAPKIAYSD SKEAVIREHY AQAKEDPYAT
1110 1120 1130 1140 1150
VGECPPAPEI SLRSDKLNET KNEYRRTTDS DQQDGKAGPP PPVIEISKAE
1160 1170 1180 1190 1200
QARRTEEYLR VKSEDDKILA KHGFTRKPEP SIEIQEPVTE QIRDDVVETA
1210 1220 1230 1240 1250
IAPEVPLRPV EELPHSPAPS SRSTPATTPK LSAKFRKDGK EGKPFDFGKS
1260 1270 1280 1290 1300
KFVCKHDVIK RGKEVEVKLE GIKLGKEDQL RVVVLPPANK AIPGANGGPP
1310 1320 1330 1340 1350
TEVDTKVKKS SSKYEISFKP TEVGTHKVFA YVNDMQHPLS PFAVRVYDAS
1360 1370 1380 1390 1400
EIIVGEIPNQ SNLNDTVEFT VDAGRAGFGN LEMAIKDADG VIIPSHVAQL
1410 1420 1430 1440 1450
ESGSAKFLVT FTPATKGPHT VNITFNKEVL KNSPFEVNIV DAPLPAPVVL
1460 1470 1480 1490 1500
EPASGASAVA SPSLSKKELK EQEKEKKREE KERAKREKEE RATLKKEKKS
1510 1520 1530 1540 1550
KSHRFPAKTT VSKIPSLSRV GQPSSLVVEV SGHDQLEIRV LDSKKSEIGT
1560 1570 1580 1590 1600
DIVEIEPGHM QINFTPAQVG DHEIDVRYGG VPVTGSPFTC RAYDPAKIKV
1610 1620 1630 1640 1650
GAIPKGLLDK PVYFTVDASE AGVGNLEVAV CEGRVPSMAH ALGHHKYDIS
1660 1670 1680 1690 1700
FVPKEDVDHT ITVRFNNEPV PGSPFLCQLV ATAQATATGA GLERIPVDEE
1710 1720 1730 1740 1750
TEIQILTDEI DSAPEARVRD PQGNDLPVNV TRSRENETLH IATYVPKCVG
1760 1770 1780 1790 1800
NHLIDIFLQG EPIAGSPFTA KAYDARKTVL VPPANAVVGK PATFVIDAAR
1810 1820 1830 1840 1850
SGAGNMEIIV SVDNRNVPNF VQAEGQARFK VSFTPQDAKD HTISVKFNGI
1860 1870 1880 1890 1900
SVPGSPLICS VSSAGSVPAA VVLPAAAVIG AETAVAARER IKHTPQHSSE
1910 1920 1930 1940 1950
QIKQTTTTVL QKTPEIRETV EKTGLARELN SAQIGQKKGF TIDNINKSSD
1960 1970 1980 1990 2000
CNVIITAPDG SMVPVSIQKS STSAYAEFTP TITGEHLVEI YLDHEIIDEF
2010 2020 2030 2040 2050
VIKIKDERHI LPPVCLAGQK YSFDVNSDDK NKVRVTIREP SGRMLPVQME
2060 2070 2080 2090 2100
DLPDGGVRVS CRFKEVGIHS IDVFVDDQPI GERKMQTVID PLNGAQLVSE
2110 2120 2130 2140 2150
PKREIVGEQT ELKILIDSGV ESQVEVIIEG PDREDNEVFV KKVSETLWSA
2160 2170 2180 2190 2200
VWTPKVEGEH ELSILVAGEQ IPGSPFPIHV LDPSAVRVIG LKNAPVGVEQ
2210 2220 2230 2240 2250
QFSVDYTNSG ASIASVEVRH GDQTIPITVK KMKPGQLLCT FTPFVDGPHQ
2260 2270 2280 2290 2300
VEVIIDGVPL SDGPYEVFIS HLGTVRASGD ALRKAQRART ARFEVINVEQ
2310 2320 2330 2340 2350
NRGELDVMVS DPKGGPLPVR CYKQQDDSYW VEFTPEHLGT HTIEVTFGDV
2360 2370 2380 2390 2400
PVPGSPFKTE VIDPKNVEIR GLSDQVLLRH ATTINVDRRN AGNGELQVEI
2410 2420 2430 2440 2450
TDPTGSPLRT EMLKSPGGED RITFLPNQTG PHKINVKVAG FQIPGYPQTI
2460 2470 2480 2490 2500
LVSEQEKPAV YGAAVDQSIK IGEPASLIFD PKKTNGGLKI HATGPDGQKV
2510 2520 2530 2540 2550
HHNVMRRPNG TSEVVFYPEE TGTYNVSIDF NNRPITGSPF TVNVVDPTKV
2560 2570 2580 2590 2600
IVNDLDMDRD GTLLLRLGHS NSFDVDATAA GPGKLRAEVR DADSSLIGNG
2610 2620 2630 2640 2650
PVVEDMGQGK YRVRFNPDQP GKYSIYLYWN ELPVESAFPV RARSSAEDLP
2660 2670 2680 2690 2700
TTSRAVREPI PPPVTTTYHT REKSSGSNAD DEISRIMVRG DGLHRAVLKE
2710 2720 2730 2740 2750
HNEFIIDGSD INKEGRITAT LLGSKADIPV RIQQLGHNVY KATYTPLTGG
2760 2770 2780 2790 2800
TYELHILWNG KHVKGSPFAV SADTSAHLAD LIDVDASTLK IGIINENIKT
2810 2820 2830 2840 2850
LIDTRRAGSG QLSALCMGPN KPAYCELYDH RDGTYALCVR PAEIGKHTLV
2860 2870 2880 2890 2900
IKYDDEHVKG SPFVVHVSLP PDPSKVRVYG PGVEHGILSL FKSNFVVETR
2910 2920 2930 2940 2950
GAGAGQLTVR VRGPKGAFNV EMQREKKNER TIHCKYEPKE PGDYQVEVKW
2960 2970 2980 2990 3000
HGEHVPGSPF LVMIVDTEKE LSRYLRGEAP SPTPATPFIP PGWVAPPQMY
3010 3020 3030
PMQPGQQRFL PPPGHFGPMG VPSPYGSVPP PTKHKGRNH
Length:3,039
Mass (Da):333,141
Last modified:November 11, 2015 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i6ACBA4282902B9CA
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 21 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
D0VWL6D0VWL6_CAEEL
FiLamiN (Actin binding protein) hom...
fln-2 C23F12.1, CELE_C23F12.1
3,611Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D0VWL8D0VWL8_CAEEL
FiLamiN (Actin binding protein) hom...
fln-2 C23F12.1, CELE_C23F12.1
2,391Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D0VWL7D0VWL7_CAEEL
FiLamiN (Actin binding protein) hom...
fln-2 C23F12.1, CELE_C23F12.1
2,776Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0K3AT80A0A0K3AT80_CAEEL
FiLamiN (Actin binding protein) hom...
fln-2 C23F12.1, CELE_C23F12.1
2,864Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0K3AYI1A0A0K3AYI1_CAEEL
FiLamiN (Actin binding protein) hom...
fln-2 C23F12.1, CELE_C23F12.1
2,656Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0K3ASN4A0A0K3ASN4_CAEEL
FiLamiN (Actin binding protein) hom...
fln-2 C23F12.1, CELE_C23F12.1
2,720Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0K3ASN9A0A0K3ASN9_CAEEL
FiLamiN (Actin binding protein) hom...
fln-2 C23F12.1, CELE_C23F12.1
2,030Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0K3AT74A0A0K3AT74_CAEEL
FiLamiN (Actin binding protein) hom...
fln-2 C23F12.1, CELE_C23F12.1
3,226Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0K3AT86A0A0K3AT86_CAEEL
FiLamiN (Actin binding protein) hom...
fln-2 C23F12.1, CELE_C23F12.1
2,271Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0K3AVH5A0A0K3AVH5_CAEEL
FiLamiN (Actin binding protein) hom...
fln-2 C23F12.1, CELE_C23F12.1
2,243Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
There are more potential isoformsShow all

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BX284606 Genomic DNA Translation: CTQ87034.1

NCBI Reference Sequences

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RefSeqi
NP_001300323.1, NM_001313394.1

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
C23F12.1h.1; C23F12.1h.1; WBGene00016006

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
181168

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284606 Genomic DNA Translation: CTQ87034.1
RefSeqiNP_001300323.1, NM_001313394.1

3D structure databases

SMRiA0A0K3AW96
ModBaseiSearch...

Proteomic databases

PeptideAtlasiA0A0K3AW96

Genome annotation databases

EnsemblMetazoaiC23F12.1h.1; C23F12.1h.1; WBGene00016006
GeneIDi181168

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
181168
WormBaseiC23F12.1h ; CE50504 ; WBGene00016006 ; fln-2

Phylogenomic databases

OrthoDBi35998at2759

Gene expression databases

ExpressionAtlasiA0A0K3AW96, baseline and differential

Family and domain databases

Gene3Di2.60.40.10, 23 hits
InterProiView protein in InterPro
IPR017868, Filamin/ABP280_repeat-like
IPR001298, Filamin/ABP280_rpt
IPR013783, Ig-like_fold
IPR014756, Ig_E-set
PfamiView protein in Pfam
PF00630, Filamin, 11 hits
SMARTiView protein in SMART
SM00557, IG_FLMN, 22 hits
SUPFAMiSSF81296, SSF81296, 23 hits
PROSITEiView protein in PROSITE
PS50194, FILAMIN_REPEAT, 23 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A0K3AW96_CAEEL
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A0K3AW96
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 11, 2015
Last sequence update: November 11, 2015
Last modified: August 12, 2020
This is version 33 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
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