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Entry version 21 (10 Apr 2019)
Sequence version 1 (11 Nov 2015)
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Protein
Submitted name:

Prion-like-(Q/N-rich)-domain-bearing protein

Gene

pqn-80

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionPrionImported

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Prion-like-(Q/N-rich)-domain-bearing proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:pqn-80Imported
ORF Names:CELE_Y111B2A.14Imported, Y111B2A.14Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCaenorhabditis elegansImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6239 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditinaRhabditomorphaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001940 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome III

Organism-specific databases

WormBase

More...
WormBasei
Y111B2A.14e ; CE50433 ; WBGene00004161 ; pqn-80

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

    Keywords - Cellular componenti

    Amyloid

    <p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

    Gene expression databases

    ExpressionAtlas, Differential and Baseline Expression

    More...
    ExpressionAtlasi
    A0A0K3AU63 baseline and differential

    <p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

    3D structure databases

    SWISS-MODEL Repository - a database of annotated 3D protein structure models

    More...
    SMRi
    A0A0K3AU63

    Database of comparative protein structure models

    More...
    ModBasei
    Search...

    MobiDB: a database of protein disorder and mobility annotations

    More...
    MobiDBi
    Search...

    <p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

    Coiled coil

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili697 – 784Sequence analysisAdd BLAST88
    Coiled coili796 – 822Sequence analysisAdd BLAST27
    Coiled coili848 – 879Sequence analysisAdd BLAST32

    Keywords - Domaini

    Coiled coilSequence analysis

    Phylogenomic databases

    Database of Orthologous Groups

    More...
    OrthoDBi
    1477245at2759

    <p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

    <p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

    This entry has 1 described isoform and 16 potential isoforms that are computationally mapped.Show allAlign All

    A0A0K3AU63-1 [UniParc]FASTAAdd to basket
    « Hide
            10         20         30         40         50
    MTGAPPSIRM VSSSSSLKKL PAPRKPSPPP AVEPTRSVEI IEKPEKTEKP
    60 70 80 90 100
    AEKRKTAATT SALEPAEKKK KPDSSSSSEE IILIDDNAPA AKKQPESAQK
    110 120 130 140 150
    GSTTVTMSAK KICKQQEEIA KQKPSSSSVT PSKPAAPTAS TPKKEEIGTL
    160 170 180 190 200
    ETFLKNIFAN LDAKGKLYQE KKLKTFDTET LKEITTFIDV MKHHKTEKVN
    210 220 230 240 250
    MEPLIYSLAK SFGMTTQEVM KQVEQEISSK KATTPKPSTN AVLSTISSQK
    260 270 280 290 300
    SLEKNAADWK LTQTDLPTMG EKDIQMLTTI VRSWKSKKEI SNSMVTGWLK
    310 320 330 340 350
    DVNQLKMNAD QARKKFFDII NTLPDSSEKN GGGGQQDAND IPKHERSRKA
    360 370 380 390 400
    RMFLHQWVYL SRKFLELQLP KLKHHSPPVE GLAKKQVIAA NAIKEGVRKQ
    410 420 430 440 450
    ISLFENKKET SSRLPGDPVY VFQFTEPVLT AVAPYLEDLV DYALAAKKIE
    460 470 480 490 500
    LIVSGIDALH QSTDGKITII QFYIEICRRL QKLSFLAVEE PMKSRLKEAN
    510 520 530 540 550
    EQIMKHQVVQ IPKYQLKWPD GQAEPSLKGL NRELYEFDKS ILSMVAAKPS
    560 570 580 590 600
    APATPKASSS TALRPSTSST PSQQQSTSTA KAMTSSSTSA EDAKRLLAMN
    610 620 630 640 650
    QLVQVYAGKY LLPTGNSTAD ICDPTICLMN DDILLIMVTA VYSCGIPLVN
    660 670 680 690 700
    QMNMLKNVLC QVGQTRMAQT LATQKTQNKQ CLTQNDYQLL FDYFGKFEKA
    710 720 730 740 750
    LEQRKAKKEE AERLKKLEEK LKKEKEKQAE KDRIEAKKFE ERMKKEQEKQ
    760 770 780 790 800
    EEKERKEREK REEKERKERE IREIMERKKR EEDDRIAAKL QIAQQLENDR
    810 820 830 840 850
    KMREAEESAR KETERRAKME TEAANALQGL EEDLLMDDID FMTQQQTKVD
    860 870 880 890 900
    EERKVAEARR AVERENQIKM MRAQQLQRRQ EEAPPPQQAP APHTQKIQVK
    910 920 930 940 950
    NEPVDHSFDI LKEAEKDAHI IPTKSIKAEP LDVQKPLSAF EKLASLRGRT
    960 970 980 990 1000
    QSADMRRGGD STEMPNVTQQ YQAEQNHLAQ SSNNSQYNAP STSSQPQHFP
    1010 1020 1030 1040 1050
    TEPSIRQPPP QQSYNSNQML QNPRQQPQNQ IVQNFQSAPQ RHPHQNPQIA
    1060 1070 1080 1090 1100
    TSSSSGGVNQ FYNNGGAAPP VVEQQAANRR SSFTMSHSVQ QHQSPLQQQF
    1110 1120 1130 1140 1150
    PINSYQSPSH HNNSSSMSNS SLMQTPHSNS SMIARSPQFP SHTSPMSQRF
    1160 1170 1180 1190 1200
    HTPPSVGHQM VQSPLSQPNP SPLQHFNFSP HSSSFSSQRP QMPPQRQMSQ
    1210 1220 1230 1240 1250
    QNLMHQQQQP QNHTQHQYQH QTFSSQQQQL QQHQHQIRHQ MNTNYPPPPG

    YNHHGH
    Length:1,256
    Mass (Da):142,171
    Last modified:November 11, 2015 - v1
    <p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i978ABEFA64E25E55
    GO

    <p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

    There are 16 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
    EntryEntry nameProtein names
    Gene namesLengthAnnotation
    C7IVS6C7IVS6_CAEEL
    Prion-like-(Q/N-rich)-domain-bearin...
    pqn-80 CELE_Y111B2A.14, Y111B2A.14
    1,446Annotation score:

    Annotation score:1 out of 5

    <p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
    C7IVS5C7IVS5_CAEEL
    Prion-like-(Q/N-rich)-domain-bearin...
    pqn-80 CELE_Y111B2A.14, Y111B2A.14
    1,416Annotation score:

    Annotation score:1 out of 5

    <p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
    A0A0K3AX73A0A0K3AX73_CAEEL
    Prion-like-(Q/N-rich)-domain-bearin...
    pqn-80 CELE_Y111B2A.14, Y111B2A.14
    1,449Annotation score:

    Annotation score:1 out of 5

    <p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
    A0A0K3ARW1A0A0K3ARW1_CAEEL
    Prion-like-(Q/N-rich)-domain-bearin...
    pqn-80 CELE_Y111B2A.14, Y111B2A.14
    1,419Annotation score:

    Annotation score:1 out of 5

    <p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
    A0A0K3ARB9A0A0K3ARB9_CAEEL
    Prion-like-(Q/N-rich)-domain-bearin...
    pqn-80 CELE_Y111B2A.14, Y111B2A.14
    1,063Annotation score:

    Annotation score:1 out of 5

    <p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
    A0A0K3AX79A0A0K3AX79_CAEEL
    Prion-like-(Q/N-rich)-domain-bearin...
    pqn-80 CELE_Y111B2A.14, Y111B2A.14
    1,223Annotation score:

    Annotation score:1 out of 5

    <p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
    A0A0K3AX82A0A0K3AX82_CAEEL
    Prion-like-(Q/N-rich)-domain-bearin...
    pqn-80 CELE_Y111B2A.14, Y111B2A.14
    590Annotation score:

    Annotation score:1 out of 5

    <p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
    A0A0K3ARW5A0A0K3ARW5_CAEEL
    Prion-like-(Q/N-rich)-domain-bearin...
    pqn-80 CELE_Y111B2A.14, Y111B2A.14
    1,066Annotation score:

    Annotation score:1 out of 5

    <p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
    A0A0K3AUW7A0A0K3AUW7_CAEEL
    Prion-like-(Q/N-rich)-domain-bearin...
    pqn-80 CELE_Y111B2A.14, Y111B2A.14
    1,253Annotation score:

    Annotation score:1 out of 5

    <p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
    A0A0K3ARX0A0A0K3ARX0_CAEEL
    Prion-like-(Q/N-rich)-domain-bearin...
    pqn-80 CELE_Y111B2A.14, Y111B2A.14
    560Annotation score:

    Annotation score:1 out of 5

    <p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
    There are more potential isoformsShow all

    Sequence databases

    Select the link destinations:

    EMBL nucleotide sequence database

    More...
    EMBLi

    GenBank nucleotide sequence database

    More...
    GenBanki

    DNA Data Bank of Japan; a nucleotide sequence database

    More...
    DDBJi
    Links Updated
    BX284603 Genomic DNA Translation: CTQ86589.1

    NCBI Reference Sequences

    More...
    RefSeqi
    NP_001299889.1, NM_001312960.1

    UniGene gene-oriented nucleotide sequence clusters

    More...
    UniGenei
    Cel.17460

    Genome annotation databases

    Ensembl metazoan genome annotation project

    More...
    EnsemblMetazoai
    Y111B2A.14e.1; Y111B2A.14e.1; WBGene00004161
    Y111B2A.14e.2; Y111B2A.14e.2; WBGene00004161
    Y111B2A.14e.3; Y111B2A.14e.3; WBGene00004161

    Database of genes from NCBI RefSeq genomes

    More...
    GeneIDi
    176683

    <p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

    <p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBLi
    GenBanki
    DDBJi
    Links Updated
    BX284603 Genomic DNA Translation: CTQ86589.1
    RefSeqiNP_001299889.1, NM_001312960.1
    UniGeneiCel.17460

    3D structure databases

    SMRiA0A0K3AU63
    ModBaseiSearch...
    MobiDBiSearch...

    Protocols and materials databases

    Structural Biology KnowledgebaseSearch...

    Genome annotation databases

    EnsemblMetazoaiY111B2A.14e.1; Y111B2A.14e.1; WBGene00004161
    Y111B2A.14e.2; Y111B2A.14e.2; WBGene00004161
    Y111B2A.14e.3; Y111B2A.14e.3; WBGene00004161
    GeneIDi176683

    Organism-specific databases

    Comparative Toxicogenomics Database

    More...
    CTDi
    176683
    WormBaseiY111B2A.14e ; CE50433 ; WBGene00004161 ; pqn-80

    Phylogenomic databases

    OrthoDBi1477245at2759

    Gene expression databases

    ExpressionAtlasiA0A0K3AU63 baseline and differential

    Family and domain databases

    ProtoNet; Automatic hierarchical classification of proteins

    More...
    ProtoNeti
    Search...

    <p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

    <p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A0K3AU63_CAEEL
    <p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A0K3AU63
    <p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 11, 2015
    Last sequence update: November 11, 2015
    Last modified: April 10, 2019
    This is version 21 of the entry and version 1 of the sequence. See complete history.
    <p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

    <p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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