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Entry version 37 (12 Aug 2020)
Sequence version 2 (31 Jul 2019)
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Protein
Submitted name:

FiLamiN (Actin binding protein) homolog

Gene

fln-2

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
FiLamiN (Actin binding protein) homologImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:fln-2Imported
ORF Names:C23F12.1Imported, CELE_C23F12.1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCaenorhabditis elegansImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6239 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditinaRhabditomorphaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001940 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

WormBase

More...
WormBasei
C23F12.1e ; CE53305 ; WBGene00016006 ; fln-2

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
A0A0K3AT74

PeptideAtlas

More...
PeptideAtlasi
A0A0K3AT74

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
A0A0K3AT74, baseline and differential

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
A0A0K3AT74

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati331 – 424FilaminPROSITE-ProRule annotationAdd BLAST94
Repeati588 – 669FilaminPROSITE-ProRule annotationAdd BLAST82
Repeati679 – 759FilaminPROSITE-ProRule annotationAdd BLAST81
Repeati757 – 851FilaminPROSITE-ProRule annotationAdd BLAST95
Repeati851 – 942FilaminPROSITE-ProRule annotationAdd BLAST92
Repeati964 – 1046FilaminPROSITE-ProRule annotationAdd BLAST83
Repeati1064 – 1133FilaminPROSITE-ProRule annotationAdd BLAST70
Repeati1803 – 1887FilaminPROSITE-ProRule annotationAdd BLAST85
Repeati1885 – 1980FilaminPROSITE-ProRule annotationAdd BLAST96
Repeati2059 – 2133FilaminPROSITE-ProRule annotationAdd BLAST75
Repeati2143 – 2220FilaminPROSITE-ProRule annotationAdd BLAST78
Repeati2218 – 2313FilaminPROSITE-ProRule annotationAdd BLAST96
Repeati2327 – 2402FilaminPROSITE-ProRule annotationAdd BLAST76
Repeati2465 – 2548FilaminPROSITE-ProRule annotationAdd BLAST84
Repeati2546 – 2639FilaminPROSITE-ProRule annotationAdd BLAST94
Repeati2637 – 2731FilaminPROSITE-ProRule annotationAdd BLAST95
Repeati2729 – 2824FilaminPROSITE-ProRule annotationAdd BLAST96
Repeati2865 – 2959FilaminPROSITE-ProRule annotationAdd BLAST95
Repeati2961 – 3054FilaminPROSITE-ProRule annotationAdd BLAST94
Repeati3055 – 3151FilaminPROSITE-ProRule annotationAdd BLAST97

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni420 – 471DisorderedSequence analysisAdd BLAST52
Regioni508 – 556DisorderedSequence analysisAdd BLAST49
Regioni1171 – 1233DisorderedSequence analysisAdd BLAST63
Regioni1248 – 1281DisorderedSequence analysisAdd BLAST34
Regioni1308 – 1376DisorderedSequence analysisAdd BLAST69
Regioni1392 – 1422DisorderedSequence analysisAdd BLAST31
Regioni1477 – 1497DisorderedSequence analysisAdd BLAST21
Regioni1640 – 1700DisorderedSequence analysisAdd BLAST61
Regioni1744 – 1771DisorderedSequence analysisAdd BLAST28
Regioni1996 – 2057DisorderedSequence analysisAdd BLAST62
Regioni2836 – 2866DisorderedSequence analysisAdd BLAST31
Regioni3200 – 3226DisorderedSequence analysisAdd BLAST27

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi439 – 471PolarSequence analysisAdd BLAST33
Compositional biasi508 – 537PolarSequence analysisAdd BLAST30
Compositional biasi538 – 556Pro-richSequence analysisAdd BLAST19
Compositional biasi1174 – 1191PolarSequence analysisAdd BLAST18
Compositional biasi1192 – 1212PolyampholyteSequence analysisAdd BLAST21
Compositional biasi1214 – 1233PolarSequence analysisAdd BLAST20
Compositional biasi1312 – 1327PolarSequence analysisAdd BLAST16
Compositional biasi1340 – 1373PolyampholyteSequence analysisAdd BLAST34
Compositional biasi1407 – 1422PolarSequence analysisAdd BLAST16
Compositional biasi1655 – 1673PolyampholyteSequence analysisAdd BLAST19
Compositional biasi2007 – 2037PolyampholyteSequence analysisAdd BLAST31
Compositional biasi3202 – 3216Pro-richSequence analysisAdd BLAST15

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00014, CH, 2 hits

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.418.10, 3 hits
2.60.40.10, 19 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001715, CH-domain
IPR036872, CH_dom_sf
IPR017868, Filamin/ABP280_repeat-like
IPR001298, Filamin/ABP280_rpt
IPR013783, Ig-like_fold
IPR014756, Ig_E-set

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00307, CH, 3 hits
PF00630, Filamin, 11 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00033, CH, 3 hits
SM00557, IG_FLMN, 19 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47576, SSF47576, 2 hits
SSF81296, SSF81296, 19 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50021, CH, 3 hits
PS50194, FILAMIN_REPEAT, 20 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 21 potential isoforms that are computationally mapped.Show allAlign All

A0A0K3AT74-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGKQGEEARQ KWIDIQLHTF TNWINEQLQG NVIRDLTQDL SDGVNLIKLV
60 70 80 90 100
EILQGRRYYG KVYDQDPTEI QKLMNVQMAL DALREDGVKT VNIGSHDIVD
110 120 130 140 150
GNEKLILGLI WCLVQRYQIA CKTKIPPKKL VMAWIQSALP ELKLTNFRTN
160 170 180 190 200
WNDGIALSAL LEYCQPGLCP EWRNLDPSEA RENCHRALLL AERYLEVPPI
210 220 230 240 250
ISSDHLSSPH LDELSCLTYL SYFITKGAPG YRATLKKVSM LLPDCNVDDL
260 270 280 290 300
EHSWSDGFLL AHLVEICGGR VPELERMRFD NLNDFVENVA IVLDAAADIG
310 320 330 340 350
VGSLIGADDI AEPQGEHLGT MALVAALCSV SLEQQVKYTD CYVNQQVNLD
360 370 380 390 400
LAFTEGNEVR IEELDVQVVG GNGQLYSNEA IKLRKSRTVQ GANLSLMPVE
410 420 430 440 450
PGFLQVRIYC QGSELPASPI SLQVHTQEET RSSSRAASRA HPENRNPPAS
460 470 480 490 500
TSKYIERTIV SPVSDSRESG KIAQFSTETE VDISHKSFAQ RRLHIIKQLE
510 520 530 540 550
AQHVNHIAQT KSHHQQHTQQ QQHHQTVPTQ SSSIVQVVQP IPPPPPTLAQ
560 570 580 590 600
SSSNIPPPPP IPAVLEASAY REMPLTRSPD VGLVSFSGLT EPCSVGSIVE
610 620 630 640 650
VVINAHGDAV SGSVYVEAVS PSGNVHRCTV RHQDNSYMAT FTPQEVGLWR
660 670 680 690 700
IGILYDGEHI RGSPFACQVF DSGLVNVYGL DVGLVGQELN FSVNASQAGH
710 720 730 740 750
GNLSVTVFRH GREIPLSIEE QGSSKVHQVS FTPDGAGQYK IHVLFNRMEI
760 770 780 790 800
KGSPFILDIA DASSVSVYGE NLRSASVGKT ASFMVHAIGA EAKDISAHVT
810 820 830 840 850
VPSGGKFPAK VVTLDDVTFQ IEWTPKEPGE HSVDVMLADQ RVPDAPFACN
860 870 880 890 900
VGAPDLVHVR NMPRRIQPSK LHTDHSFEID ASAAGSGNLE IMINGGRVPC
910 920 930 940 950
RVRELGSRQY MAIFTPTQSM THTIEMRFNG EHVSGSPWKL PVEDRGERRQ
960 970 980 990 1000
EMERTMSYYS ELSGPGLVRA PVNRTAQFDI TGEGLELSDI QAKISGPDNR
1010 1020 1030 1040 1050
EYPIRIIPRS SGKYTAEYEI EQVGEHHLTV WIAGRKVDGS PLSVAGYATE
1060 1070 1080 1090 1100
KVRLEPLGGG VPKQPVQFYV DAVEAGKGQL EISVNQGKVP NNVQMQGAGR
1110 1120 1130 1140 1150
CLVTFIPQHA GTYVIDVTFN GEQVHGCPIK VEILPKQVGQ QIHANLTPTA
1160 1170 1180 1190 1200
VSTAISAGGT SLISGAFRET ARSPLSARSP TSPTLLQHAR QRSEETMLRS
1210 1220 1230 1240 1250
PQLLRESRKA DKPWQSSYAP SSSRNAFSQS PHRDWSASTV YDRVYNSNSD
1260 1270 1280 1290 1300
VERTLSPSDP SRNRNIRETT TVIHRTPSPT GLRTQEFAER IARSPSPTGY
1310 1320 1330 1340 1350
EREFVEKRTT YRSPSPARTS SVAHSHISEV PLSPIQGMDT PFDHHERVKK
1360 1370 1380 1390 1400
VERMDPLADE EEREQRRNQL ERDSKNTLGY TVAQYGDGEK RYFGDTLEKK
1410 1420 1430 1440 1450
DRPPSAGYYS SVQQRSTSPE YSTVYERYDR KSEKPDLPPR VEGHVSASYK
1460 1470 1480 1490 1500
GYEPVYSEVT TTRTTTTTEY ENIDKKPNVP KKRATTPEGH VEPVNDNEEK
1510 1520 1530 1540 1550
DRQAFLRTQS EKVFEPVDAP LRRSDEKESI YDLPPQERLH KYPEEPTIAL
1560 1570 1580 1590 1600
GEKANTSAIA AYTKGRQDDI DEVSRNASFP SAPTINYNER SDEVSNYNRT
1610 1620 1630 1640 1650
KEDHYGVVGE YPTAPKIAYS DSKEAVIREH YAQAKEDPYA TVGECPPAPE
1660 1670 1680 1690 1700
ISLRSDKLNE TKNEYRRTTD SDQQDGKAGP PPPVIEISKA EQARRTEEYL
1710 1720 1730 1740 1750
RVKSEDDKIL AKHGFTRKPE PSIEIQEPVT EQIRDDVVET AIAPEVPLRP
1760 1770 1780 1790 1800
VEELPHSPAP SSRSTPATTP KLSAKFRKDG KEGKPFDFGK SKFVCKHDVI
1810 1820 1830 1840 1850
KRGKEVEVKL EGIKLGKEDQ LRVVVLPPAN KAIPGANGGP PTEVDTKVKK
1860 1870 1880 1890 1900
SSSKYEISFK PTEVGTHKVF AYVNDMQHPL SPFAVRVYDA SEIIVGEIPN
1910 1920 1930 1940 1950
QSNLNDTVEF TVDAGRAGFG NLEMAIKDAD GVIIPSHVAQ LESGSAKFLV
1960 1970 1980 1990 2000
TFTPATKGPH TVNITFNKEV LKNSPFEVNI VDAPLPAPVV LEPASGASAV
2010 2020 2030 2040 2050
ASPSLSKKEL KEQEKEKKRE EKERAKREKE ERATLKKEKK SKSHRFPAKT
2060 2070 2080 2090 2100
TVSKIPSLSR VGQPSSLVVE VSGHDQLEIR VLDSKKSEIG TDIVEIEPGH
2110 2120 2130 2140 2150
MQINFTPAQV GDHEIDVRYG GVPVTGSPFT CRAYDPAKIK VGAIPKGLLD
2160 2170 2180 2190 2200
KPVYFTVDAS EAGVGNLEVA VCEGRVPSMA HALGHHKYDI SFVPKEDVDH
2210 2220 2230 2240 2250
TITVRFNNEP VPGSPFLCQL VATAQATATG AGLERIPVDE ETEIQILTDE
2260 2270 2280 2290 2300
IDSAPEARVR DPQGNDLPVN VTRSRENETL HIATYVPKCV GNHLIDIFLQ
2310 2320 2330 2340 2350
GEPIAGSPFT AKAYDARKTV LVPPANAVVG KPATFVIDAA RSGAGNMEII
2360 2370 2380 2390 2400
VSVDNRNVPN FVQAEGQARF KVSFTPQDAK DHTISVKFNG ISVPGSPLIC
2410 2420 2430 2440 2450
SVSSAGSVPA AVVLPAAAVI GAETAVAARE RIKHTPQHSS EQIKQTTTTV
2460 2470 2480 2490 2500
LQKTPEIRET VEKTGLAREL NSAQIGQKKG FTIDNINKSS DCNVIITDPK
2510 2520 2530 2540 2550
GGPLPVRCYK QQDDSYWVEF TPEHLGTHTI EVTFGDVPVP GSPFKTEVID
2560 2570 2580 2590 2600
PKNVEIRGLS DQVLLRHATT INVDRRNAGN GELQVEITDP TGSPLRTEML
2610 2620 2630 2640 2650
KSPGGEDRIT FLPNQTGPHK INVKVAGFQI PGYPQTILVS EQEKPAVYGA
2660 2670 2680 2690 2700
AVDQSIKIGE PASLIFDPKK TNGGLKIHAT GPDGQKVHHN VMRRPNGTSE
2710 2720 2730 2740 2750
VVFYPEETGT YNVSIDFNNR PITGSPFTVN VVDPTKVIVN DLDMDRDGTL
2760 2770 2780 2790 2800
LLRLGHSNSF DVDATAAGPG KLRAEVRDAD SSLIGNGPVV EDMGQGKYRV
2810 2820 2830 2840 2850
RFNPDQPGKY SIYLYWNELP VESAFPVRAR SSAEDLPTTS RAVREPIPPP
2860 2870 2880 2890 2900
VTTTYHTREK SSGSNADDEI SRIMVRGDGL HRAVLKEHNE FIIDGSDINK
2910 2920 2930 2940 2950
EGRITATLLG SKADIPVRIQ QLGHNVYKAT YTPLTGGTYE LHILWNGKHV
2960 2970 2980 2990 3000
KGSPFAVSAD TSAHLADLID VDASTLKIGI INENIKTLID TRRAGSGQLS
3010 3020 3030 3040 3050
ALCMGPNKPA YCELYDHRDG TYALCVRPAE IGKHTLVIKY DDEHVKGSPF
3060 3070 3080 3090 3100
VVHVSLPPDP SKVRVYGPGV EHGILSLFKS NFVVETRGAG AGQLTVRVRG
3110 3120 3130 3140 3150
PKGAFNVEMQ REKKNERTIH CKYEPKEPGD YQVEVKWHGE HVPGSPFLVM
3160 3170 3180 3190 3200
IVDTEKELSR YLRGEAPSPT PATPFIPPGW VAPPQMYPMQ PGQQRFLPPP
3210 3220
GHFGPMGVPS PYGSVPPPTK HKGRNH
Length:3,226
Mass (Da):354,667
Last modified:July 31, 2019 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i896528AD24D1247C
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 21 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
D0VWL6D0VWL6_CAEEL
FiLamiN (Actin binding protein) hom...
fln-2 C23F12.1, CELE_C23F12.1
3,611Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D0VWL8D0VWL8_CAEEL
FiLamiN (Actin binding protein) hom...
fln-2 C23F12.1, CELE_C23F12.1
2,391Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D0VWL7D0VWL7_CAEEL
FiLamiN (Actin binding protein) hom...
fln-2 C23F12.1, CELE_C23F12.1
2,776Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0K3AT80A0A0K3AT80_CAEEL
FiLamiN (Actin binding protein) hom...
fln-2 C23F12.1, CELE_C23F12.1
2,864Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0K3AW96A0A0K3AW96_CAEEL
FiLamiN (Actin binding protein) hom...
fln-2 C23F12.1, CELE_C23F12.1
3,039Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0K3AYI1A0A0K3AYI1_CAEEL
FiLamiN (Actin binding protein) hom...
fln-2 C23F12.1, CELE_C23F12.1
2,656Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0K3ASN4A0A0K3ASN4_CAEEL
FiLamiN (Actin binding protein) hom...
fln-2 C23F12.1, CELE_C23F12.1
2,720Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0K3ASN9A0A0K3ASN9_CAEEL
FiLamiN (Actin binding protein) hom...
fln-2 C23F12.1, CELE_C23F12.1
2,030Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0K3AT86A0A0K3AT86_CAEEL
FiLamiN (Actin binding protein) hom...
fln-2 C23F12.1, CELE_C23F12.1
2,271Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0K3AVH5A0A0K3AVH5_CAEEL
FiLamiN (Actin binding protein) hom...
fln-2 C23F12.1, CELE_C23F12.1
2,243Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
There are more potential isoformsShow all

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
BX284606 Genomic DNA Translation: CTQ87031.2

NCBI Reference Sequences

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RefSeqi
NP_001300320.1, NM_001313391.1

Genome annotation databases

Ensembl metazoan genome annotation project

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EnsemblMetazoai
C23F12.1e.1; C23F12.1e.1; WBGene00016006

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284606 Genomic DNA Translation: CTQ87031.2
RefSeqiNP_001300320.1, NM_001313391.1

3D structure databases

SMRiA0A0K3AT74
ModBaseiSearch...

Proteomic databases

EPDiA0A0K3AT74
PeptideAtlasiA0A0K3AT74

Genome annotation databases

EnsemblMetazoaiC23F12.1e.1; C23F12.1e.1; WBGene00016006

Organism-specific databases

WormBaseiC23F12.1e ; CE53305 ; WBGene00016006 ; fln-2

Gene expression databases

ExpressionAtlasiA0A0K3AT74, baseline and differential

Family and domain databases

CDDicd00014, CH, 2 hits
Gene3Di1.10.418.10, 3 hits
2.60.40.10, 19 hits
InterProiView protein in InterPro
IPR001715, CH-domain
IPR036872, CH_dom_sf
IPR017868, Filamin/ABP280_repeat-like
IPR001298, Filamin/ABP280_rpt
IPR013783, Ig-like_fold
IPR014756, Ig_E-set
PfamiView protein in Pfam
PF00307, CH, 3 hits
PF00630, Filamin, 11 hits
SMARTiView protein in SMART
SM00033, CH, 3 hits
SM00557, IG_FLMN, 19 hits
SUPFAMiSSF47576, SSF47576, 2 hits
SSF81296, SSF81296, 19 hits
PROSITEiView protein in PROSITE
PS50021, CH, 3 hits
PS50194, FILAMIN_REPEAT, 20 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A0K3AT74_CAEEL
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A0K3AT74
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 11, 2015
Last sequence update: July 31, 2019
Last modified: August 12, 2020
This is version 37 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
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