Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

UniProtKB - A0A0K1RMV2 (A0A0K1RMV2_9GAMC)

Entry version 27 (02 Dec 2020)
Sequence version 1 (11 Nov 2015)
Previous versions | rss
Add a publicationFeedback
Protein

3C-like proteinase

Gene

IBVgp1

Organism
Infectious bronchitis virus
Status
Unreviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Nsp7-nsp8 hexadecamer may possibly confer processivity to the polymerase, maybe by binding to dsRNA or by producing primers utilized by the latter.ARBA annotation
Nsp9 is a ssRNA-binding protein.ARBA annotation
The papain-like proteinase (PL-PRO) is responsible for the cleavages located at the N-terminus of replicase polyprotein. Activity of PL-PRO is dependent on zinc.ARBA annotation
The peptide p16 might be involved in the EGF signaling pathway.ARBA annotation

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolase, Protease, RNA-bindingARBA annotation, Thiol proteaseARBA annotation
Biological processActivation of host autophagy by virusARBA annotation, Host-virus interaction
LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
3C-like proteinaseARBA annotation
Alternative name(s):
Growth factor-like peptideARBA annotation
M-PROARBA annotation
Non-structural protein 10ARBA annotation
Non-structural protein 2ARBA annotation
Non-structural protein 3ARBA annotation
Non-structural protein 4ARBA annotation
Non-structural protein 6ARBA annotation
Non-structural protein 7ARBA annotation
Non-structural protein 8ARBA annotation
Non-structural protein 9ARBA annotation
Papain-like proteinaseARBA annotation
Peptide HD2ARBA annotation
nsp5ARBA annotation
p10ARBA annotation
p16ARBA annotation
p195ARBA annotation
p24ARBA annotation
p33ARBA annotation
p34ARBA annotation
p41ARBA annotation
p87ARBA annotation
p9ARBA annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:IBVgp1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiInfectious bronchitis virusImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri11120 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiViruses › Riboviria › Orthornavirae › Pisuviricota › Pisoniviricetes › Nidovirales › Cornidovirineae › Coronaviridae › Orthocoronavirinae › Gammacoronavirus › Igacovirus ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000151562 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Genome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei1721 – 1739HelicalSequence analysisAdd BLAST19
Transmembranei1745 – 1765HelicalSequence analysisAdd BLAST21
Transmembranei1846 – 1873HelicalSequence analysisAdd BLAST28
Transmembranei2283 – 2301HelicalSequence analysisAdd BLAST19
Transmembranei2560 – 2581HelicalSequence analysisAdd BLAST22
Transmembranei2588 – 2608HelicalSequence analysisAdd BLAST21
Transmembranei2614 – 2632HelicalSequence analysisAdd BLAST19
Transmembranei2644 – 2669HelicalSequence analysisAdd BLAST26
Transmembranei3099 – 3119HelicalSequence analysisAdd BLAST21
Transmembranei3125 – 3142HelicalSequence analysisAdd BLAST18
Transmembranei3154 – 3172HelicalSequence analysisAdd BLAST19
Transmembranei3192 – 3210HelicalSequence analysisAdd BLAST19
Transmembranei3222 – 3240HelicalSequence analysisAdd BLAST19
Transmembranei3260 – 3283HelicalSequence analysisAdd BLAST24
Transmembranei3295 – 3322HelicalSequence analysisAdd BLAST28

GO - Cellular componenti

Complete GO annotation on QuickGO ...

Keywords - Cellular componenti

Host cytoplasmARBA annotation, Host membraneARBA annotation, Membrane

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1005 – 1181MacroInterPro annotationAdd BLAST177
Domaini1238 – 1499Peptidase C16InterPro annotationAdd BLAST262
Domaini2782 – 3088Peptidase C30InterPro annotationAdd BLAST307

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni783 – 817DisorderedSequence analysisAdd BLAST35

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the coronaviruses polyprotein 1ab family.ARBA annotation

Keywords - Domaini

RepeatARBA annotation, Transmembrane, Transmembrane helixSequence analysisARBA annotation, Zinc-fingerARBA annotation

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.10.150.420, 1 hit
1.10.1840.10, 1 hit
1.10.8.370, 1 hit
2.40.10.10, 2 hits
2.40.10.250, 1 hit
2.40.10.290, 1 hit
3.40.220.10, 1 hit
3.90.70.90, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR043611, CoV_NSP3_C
IPR043612, CoV_NSP4_N
IPR043610, CoV_NSP6
IPR002589, Macro_dom
IPR043472, Macro_dom-like
IPR036333, NSP10_sf_CoV
IPR040795, Nsp1a_N
IPR032505, NSP4_C_CoV
IPR038123, NSP4_C_sf_CoV
IPR014828, NSP7_CoV
IPR037204, NSP7_sf_CoV
IPR014829, NSP8_CoV-like
IPR037230, NSP8_sf_CoV
IPR014822, NSP9_CoV
IPR036499, NSP9_sf_CoV
IPR013016, Peptidase_C16_CoV
IPR008740, Peptidase_C30_CoV
IPR043477, Peptidase_C30_dom3_CoV
IPR009003, Peptidase_S1_PA
IPR043504, Peptidase_S1_PA_chymotrypsin
IPR043503, PLpro_palm_finger_dom_CoV
IPR018995, RNA_synth_NSP10_CoV

Pfam protein domain database

More...Pfami		View protein in Pfam
PF09401, CoV_NSP10, 1 hit
PF19218, CoV_NSP3_C, 1 hit
PF16348, CoV_NSP4_C, 1 hit
PF19217, CoV_NSP4_N, 1 hit
PF19213, CoV_NSP6, 1 hit
PF08716, CoV_NSP7, 1 hit
PF08717, CoV_NSP8, 1 hit
PF08710, CoV_NSP9, 1 hit
PF08715, CoV_peptidase, 1 hit
PF01661, Macro, 1 hit
PF17896, Nsp2a_N, 1 hit
PF05409, Peptidase_C30, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00506, A1pp, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF101816, SSF101816, 1 hit
SSF140367, SSF140367, 1 hit
SSF143076, SSF143076, 1 hit
SSF144246, SSF144246, 1 hit
SSF50494, SSF50494, 1 hit
SSF52949, SSF52949, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS51442, M_PRO, 1 hit
PS51154, MACRO, 1 hit
PS51124, PEPTIDASE_C16, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A0K1RMV2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MASSLKQGVS PKLRDVILVS KDIPEQLCDA LFFYTSHNPK DYADAFAVRH 
        60         70         80         90        100
KFDRSLQTGK QFKFETVCGL FLLKGVDKIT PGVPAKVLKS TSKLADLEDI 
       110        120        130        140        150
FGVSPFARKY RHLLKTACQW SLTVETLDAR AQTLDEIFDP TEILWLQVAA 
       160        170        180        190        200
KIQVSAMAMR RLVGEVTAKV MEALGSNLSA LFQIVKQQIA RIFQKALAIF 
       210        220        230        240        250
ENVSELPQRI AALKMAFAKC AKSITVVVVE RTLIVKEFAG TCLASINGAV 
       260        270        280        290        300
AKFFEELPNG FMGSKIFTTL AFFKEAAVKI VENIPNAPRG TKGFEVVGNA 
       310        320        330        340        350
KGTQVVVRGM RNDLTLLDQK VEIPVESEGW SAILEGHLCY VFKSGDRFYA 
       360        370        380        390        400
APLSGNFALH DVHCCERVVC LSDGVTPEIN DGLILAAIYS SFSVSELMAA 
       410        420        430        440        450
LKKGEPFKFL GHKFVYAKDA AVSFTLAKAA TIADVLKLFQ SARAKVEDVW 
       460        470        480        490        500
SSFTEKSFEF WKLAYGKVRI LEDFVRPQLV RLKWSMGILA TVLGEGIWHL 
       510        520        530        540        550
VSQVIYKVGG LFTKVVDFCE KYWKGFCAQL KRPKLIVTET LCVLKGVAQH 
       560        570        580        590        600
CFQLLLDAIH SMYKSFKKCA LGRIHGDLLF WKGGVHKIIQ EGDEIWFDAI 
       610        620        630        640        650
DSIDVEDLGV VQEKSIDFEV CDNVTLPENQ PGHMVQIQNE DKNYMFFRFK 
       660        670        680        690        700
KDENIYYTPM SQLGVINVVC KAGGKTVTFG ETTVQEIPPP DVVPIKVSIE 
       710        720        730        740        750
CCGEHGTQFS RKPIKEPIEV ETDFTVEQLL SVIYEKMCDD LKLFPEAPEP 
       760        770        780        790        800
PPFEKVSLVE KQGKDLDCIK SCHWIYRDYE SDDDIEEEDA EECDTDSGDA 
       810        820        830        840        850
EECDTNSECE EEDEDTKGLA LIQDQPSYKY PLPLEEDYSV YNGCIVHKDA 
       860        870        880        890        900
LDVVNLPSGE ETFVVNDCFE GAVKPLPQKV IDVLGDWGEA VDAQEQLCQQ 
       910        920        930        940        950
ESTQAAFERS VEDSIGGCEA MAEQSVVDEH ELLLVVEENQ HGVVYTPADL 
       960        970        980        990       1000
EGVKETAEEV DEFILIADVS KEEVVPQGKG ESQVEQEPIQ VVKSQREKKA 
      1010       1020       1030       1040       1050
KKFRVKPATC EKPKFLEYKT CVGDLTVVIA KALDEFKEFC IVNAANEHMS 
      1060       1070       1080       1090       1100
HGGGVAKAIA DFFGPDFVEY CEDYVKKHGP QQRLVTPSFV KGIQCENNVV 
      1110       1120       1130       1140       1150
GLRHGDINSR QKLVAAYKNV LVDGVVNYAV PVLSLGIFGV DFKMSIDAMR 
      1160       1170       1180       1190       1200
EAFEGCTIRV LLFSLSQEHI DYFDVTCKQK TLYLTEDGVK YRSVVVKPGD 
      1210       1220       1230       1240       1250
SLSQFGQVFA KNKAVFTADD VEDKEILFVP TTDKTVLEYY PLDAQKYVIY 
      1260       1270       1280       1290       1300
LQTLAQKWNV QYRDNFLILE WRDGNCWISS AIVLLQAAKI RFKGFLSEAW 
      1310       1320       1330       1340       1350
AKLLGGDPTD FVAWCYASCN AKVGDFSDAN WLLANFAEHF DADYKNAFLK 
      1360       1370       1380       1390       1400
KRVSCNCGVK SYELRGLEAC IQPVRATNLL HFKTQYSNCP TSGASNTDEV 
      1410       1420       1430       1440       1450
FEASLPYLLL FATDGPATVD CDEDAVGTVV FVGSTNSVHC DTQAARQAFD 
      1460       1470       1480       1490       1500
NLAKDRKFGK KSPYKTAMYT RFAFKNENPL PVAKHSKGKS KSVKEDVSNL 
      1510       1520       1530       1540       1550
ATSSKASFDN LTDFEQWYTS NIYESLKVQE SPYNFDKYVS FKIKEDSKLQ 
      1560       1570       1580       1590       1600
KTLKVRCIKS VFDFRSKDGF IYKLSPDTDE NSKAPVYYPV LDSISLRAIW 
      1610       1620       1630       1640       1650
VEGSANFVVG HPNYYSKFLH IPTFWENAEN FVKMGDKIGG VSMGLWRAEH 
      1660       1670       1680       1690       1700
LNKPNLERIF NIAKKAIVGS SVVTTQCGKL FGKAATFVAD KVGDGVVRNI 
      1710       1720       1730       1740       1750
TDSIKGLCGF TRGHFERKMS LQFLKTLMFF LFYFLKASVK SVVSSYKIVL 
      1760       1770       1780       1790       1800
CKVVFVTLLI VWIVYTSNPV MFTGIRVLDF VFEGSLCGPY KDYGKDSFDV 
      1810       1820       1830       1840       1850
LRNCAGDFTC RVCLHDRDSL HLFKYAYSVE QIYKDAASGI NFNWNWLYLV 
      1860       1870       1880       1890       1900
FLILFVKPVA GFVIICYCVK YLVLSSTVLQ TGVGFLDWFV KTVFSHFNFM 
      1910       1920       1930       1940       1950
GAGFYFWLFY KIYVQVHHIL YCKDGTCGVC KRVARSTRQE VSVVVGGRQQ 
      1960       1970       1980       1990       2000
IVHVYTNSGY NFCKRHNWYC RNCDDYGHQN TFMSPEVAGE LSEKLKRHVK 
      2010       2020       2030       2040       2050
PTAYAYPVVD EACLVDDFVN LKYKAATPGK DNASSAVKCF SVTNFLKKAV 
      2060       2070       2080       2090       2100
FLKEALKCEQ ISNDGFIVCN TQSAHALEEA KNAAVYYAQY LCKPILILDQ 
      2110       2120       2130       2140       2150
ALYEQLIVEP VSKSVVDKVC SILSNIISVD TAALNYKAGT LRDALLSITK 
      2160       2170       2180       2190       2200
DEEAVDMAIF CHNHEVEYTG DGFTNVIPSY GIDIDKLTPR DRGFLINADA 
      2210       2220       2230       2240       2250
SIANLRVKNA PPVVWKFSEL IKLSDSCLKY LISATVKSGV RFFITKSGVK 
      2260       2270       2280       2290       2300
QVIACHTQKL LVEKKAGGVI SGTFKWFMSC FKWLLIFEIL FTACCLGYYY 
      2310       2320       2330       2340       2350
LEVNKSFVHP MYDVNSTLHF EGFQVIDNGV LRDIVPEDNC FSNKSVNFDA 
      2360       2370       2380       2390       2400
FWGKSYENNK NCPIVTVVID GHGTVAVGFP GFVSWVMDGV MFVHKTQTDR 
      2410       2420       2430       2440       2450
RPWYIPTWFN TDIVGYTQDS NITEDSFYTS IALFSARCLY LSASNTRQLY 
      2460       2470       2480       2490       2500
CFNRENDAPG ALPFGSIIPH RVYFQPKGVR LKVPQQILHT PYLVKLVSDS 
      2510       2520       2530       2540       2550
YCRGSVCEYT KPGYRVSLDP QWVLFNDEYT SKPGVFCGST VRELMFNMVS 
      2560       2570       2580       2590       2600
TFFTGVNPNI YMQLATMFLI LVVIVLIFAM VIKFQGVFKA YATIVFTIML 
      2610       2620       2630       2640       2650
VWVINAFVLC VHSYNSVLAV ILLVLYCYAS LVKSRNTGII MHCGLVTMVG 
      2660       2670       2680       2690       2700
LIVPTCLSCC FLGFILYMYT PLFFWCYGTT KNTRKLYDGN EFVGNYDLAA 
      2710       2720       2730       2740       2750
KSTFVIRGSE FVKLTNEIGD KFEAYLSAYA RLNYYSGTGS EQDYLQACRA 
      2760       2770       2780       2790       2800
WLAYALDQYR NSGVEIVYLP PRYSIGVSRL QTGFKKLVSP SSAVEKCIVS 
      2810       2820       2830       2840       2850
VSYRGNNLNG LWLGDTIYCP RHVLGKFSGD QWNDVLNLAN NHEFEVTTQH 
      2860       2870       2880       2890       2900
GVTLNVVSRR LEGAVLILQT AVANAETPKY KFVKANCGDS FTIACSYGGT 
      2910       2920       2930       2940       2950
VVGLYPVTMR SNGTIRASFL AGACGSVGFN IEKGVVNFFY MHHLELPNAL 
      2960       2970       2980       2990       3000
HTGTDLTGEF YGGLVDEEVA QRVPPDNLVT NNIVAWLYAA IISVKESSFS 
      3010       3020       3030       3040       3050
QPKWLESTTV SIEDYNKWAS DNGLTPFSTS TAITKLCAIS GIDVCKLLRT 
      3060       3070       3080       3090       3100
IMVESAQWGS EPILGQYNFE DEYTPESVFN QIGGVRLQSS FVSKATSWFW 
      3110       3120       3130       3140       3150
SRCVLACFLF VLCAIVLFTA VPLKFYVYAA VILLLAVFFI SFTVKHVMAY 
      3160       3170       3180       3190       3200
MDTFLLPTLI TVIIGVCAEV PFMYNTLISQ VVIFLSQWYD PVFFDTMVPW 
      3210       3220       3230       3240       3250
MLLPLVLYTA FKCVQGCYMN SFNTSLLMLY QFMKFGFGIY TSSNTLTAYT 
      3260       3270       3280       3290       3300
EGNWELFFEL VHTTVLANVS SNSLFGLFVF KCAKWMLYYC NATYLYNYVL 
      3310       3320       3330       3340       3350
LAVMVNCIGW LCTCYFGLYW WVNKVFGLSF GKYNFKVSVD QYRYMCLHKI 
      3360       3370       3380       3390       3400
YPPKTVWEVF TTNILIQGIG GDRVFPISTV QSKLSDVKCT TVVLMQLLTK 
      3410       3420       3430       3440       3450
LNVEANSKMH AYLVELHNKI LASDDVGECM DNLLGMLITL FCIDSTIDLG 
      3460       3470       3480       3490       3500
EYCDDILKRS TVLQSVTQEF SHIPSYAEYE RAKSIYEKVL ADSKNGGVTQ 
      3510       3520       3530       3540       3550
QELAAYRNAA NIAKSVFDRD LAVQKKLDSM AERAMTTMYK EARVTDRRAK 
      3560       3570       3580       3590       3600
LVSSLHALLF SMLKKIDSEK LNVLFDQANS GVVPLATVPI VCSNKLTLVI 
      3610       3620       3630       3640       3650
PDPETWVKCV EVMHVTYSTV VWNIDCVTDA DGTELHPTST GSGLTYCISG 
      3660       3670       3680       3690       3700
DNIAWPLKVN LTRNGHNKVD VALQNNELMP HGVKTKACVA GVDQAHCSVE 
      3710       3720       3730       3740       3750
SKCYYTSISG SSVVAAITSS NSNLKVASFL NEAGNQIYVD LDPPCKFGMK 
      3760       3770       3780       3790       3800
VGDKVEVVYL YLIKNTRSIV RGMVLGAISN VVVLQSKGHE TEEVDAVGIL 
      3810       3820       3830       3840       3850
SLCSFAVDPA DTYCKYVAAG NQPLGNCVKM LTVHNGSGFA ITSKPSPTPD 
      3860       3870       3880       3890       3900
QDSYGGVSVC LYCRAHIAHP GGAGNLDARC QFKGSFVQIP TTEKDPVGFC 
      3910       3920       3930       3940       3950
LRNKVCTVCQ CWIGYGCQCD LLRQPKPSVQ SVAVASDFDK NYLNRVRGGS 
      3960       3970       3980 
AARLLPLAHG CGPMLYGEPL MFVIRNQPVC FKI
Length:3,983
Mass (Da):445,499
Last modified:November 11, 2015 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i113B9CBAC46BD323
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
KR902510 Genomic RNA Translation: AKV63204.1

Keywords - Coding sequence diversityi

Ribosomal frameshiftingARBA annotation

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KR902510 Genomic RNA Translation: AKV63204.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Family and domain databases

Gene3Di1.10.150.420, 1 hit
1.10.1840.10, 1 hit
1.10.8.370, 1 hit
2.40.10.10, 2 hits
2.40.10.250, 1 hit
2.40.10.290, 1 hit
3.40.220.10, 1 hit
3.90.70.90, 1 hit
InterProiView protein in InterPro
IPR043611, CoV_NSP3_C
IPR043612, CoV_NSP4_N
IPR043610, CoV_NSP6
IPR002589, Macro_dom
IPR043472, Macro_dom-like
IPR036333, NSP10_sf_CoV
IPR040795, Nsp1a_N
IPR032505, NSP4_C_CoV
IPR038123, NSP4_C_sf_CoV
IPR014828, NSP7_CoV
IPR037204, NSP7_sf_CoV
IPR014829, NSP8_CoV-like
IPR037230, NSP8_sf_CoV
IPR014822, NSP9_CoV
IPR036499, NSP9_sf_CoV
IPR013016, Peptidase_C16_CoV
IPR008740, Peptidase_C30_CoV
IPR043477, Peptidase_C30_dom3_CoV
IPR009003, Peptidase_S1_PA
IPR043504, Peptidase_S1_PA_chymotrypsin
IPR043503, PLpro_palm_finger_dom_CoV
IPR018995, RNA_synth_NSP10_CoV
PfamiView protein in Pfam
PF09401, CoV_NSP10, 1 hit
PF19218, CoV_NSP3_C, 1 hit
PF16348, CoV_NSP4_C, 1 hit
PF19217, CoV_NSP4_N, 1 hit
PF19213, CoV_NSP6, 1 hit
PF08716, CoV_NSP7, 1 hit
PF08717, CoV_NSP8, 1 hit
PF08710, CoV_NSP9, 1 hit
PF08715, CoV_peptidase, 1 hit
PF01661, Macro, 1 hit
PF17896, Nsp2a_N, 1 hit
PF05409, Peptidase_C30, 1 hit
SMARTiView protein in SMART
SM00506, A1pp, 1 hit
SUPFAMiSSF101816, SSF101816, 1 hit
SSF140367, SSF140367, 1 hit
SSF143076, SSF143076, 1 hit
SSF144246, SSF144246, 1 hit
SSF50494, SSF50494, 1 hit
SSF52949, SSF52949, 1 hit
PROSITEiView protein in PROSITE
PS51442, M_PRO, 1 hit
PS51154, MACRO, 1 hit
PS51124, PEPTIDASE_C16, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A0K1RMV2_9GAMC
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A0K1RMV2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 11, 2015
Last sequence update: November 11, 2015
Last modified: December 2, 2020
This is version 27 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again