Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Poly(U)-binding-splicing factor PUF60

Gene

PUF60

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionRNA-bindingPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Poly(U)-binding-splicing factor PUF60Imported
Gene namesi
Name:PUF60Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 8

Organism-specific databases

HGNCiHGNC:17042 PUF60

PTM / Processingi

Proteomic databases

PeptideAtlasiA0A0J9YVR6

Structurei

3D structure databases

ProteinModelPortaliA0A0J9YVR6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini103 – 181RRMInterPro annotationAdd BLAST79
Domaini200 – 278RRMInterPro annotationAdd BLAST79

Family and domain databases

CDDicd12370 RRM1_PUF60, 1 hit
cd12371 RRM2_PUF60, 1 hit
Gene3Di3.30.70.330, 2 hits
InterProiView protein in InterPro
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR006532 PolyU-bd
IPR034209 PUF60_RRM1
IPR034211 PUF60_RRM2
IPR035979 RBD_domain_sf
IPR000504 RRM_dom
PfamiView protein in Pfam
PF00076 RRM_1, 2 hits
SMARTiView protein in SMART
SM00360 RRM, 2 hits
SUPFAMiSSF54928 SSF54928, 2 hits
TIGRFAMsiTIGR01645 half-pint, 1 hit
PROSITEiView protein in PROSITE
PS50102 RRM, 2 hits

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 12 potential isoforms that are computationally mapped.Show allAlign All

A0A0J9YVR6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
VNGQQGGGSE PAAAAAVVAA GDKWKPPQGT DSIKMENGQS TAAKLGLPPL
60 70 80 90 100
TPEQQEALQK AKKYAMEQSI KSVLVKQTIA HQQQQLTNLQ MAAQRQRALA
110 120 130 140 150
IMCRVYVGSI YYELGEDTIR QAFAPFGPIK SIDMSWDSVT MKHKGFAFVE
160 170 180 190 200
YEVPEAAQLA LEQMNSVMLG GRNIKVGRPS NIGQAQPIID QLAEEARAFN
210 220 230 240 250
RIYVASVHQD LSDDDIKSVF EAFGKIKSCT LARDPTTGKH KGYGFIEYEK
260 270 280 290 300
AQSSQDAVSS MNLFDLGGQY LRVGKAVTPP MPLLTPATPG GLPPAAAVAA
310
AAATAKITAQ VRAH
Length:314
Mass (Da):33,655
Last modified:October 5, 2016 - v3
Checksum:iEA92EF0D60CA8361
GO

Computationally mapped potential isoform sequencesi

There are 12 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9UHX1PUF60_HUMAN
Poly(U)-binding-splicing factor PUF...
PUF60 FIR, ROBPI, SIAHBP1
559Annotation score:
H0YEM1H0YEM1_HUMAN
Poly(U)-binding-splicing factor PUF...
PUF60
336Annotation score:
E9PQ56E9PQ56_HUMAN
Poly(U)-binding-splicing factor PUF...
PUF60
322Annotation score:
E9PMU7E9PMU7_HUMAN
Poly(U)-binding-splicing factor PUF...
PUF60
247Annotation score:
E9PL19E9PL19_HUMAN
Poly(U)-binding-splicing factor PUF...
PUF60
228Annotation score:
E9PN18E9PN18_HUMAN
Poly(U)-binding-splicing factor PUF...
PUF60
263Annotation score:
H0YCP8H0YCP8_HUMAN
Poly(U)-binding-splicing factor PUF...
PUF60
273Annotation score:
A0A0J9YXJ8A0A0J9YXJ8_HUMAN
Poly(U)-binding-splicing factor PUF...
PUF60
522Annotation score:
A0A0J9YYL3A0A0J9YYL3_HUMAN
Poly(U)-binding-splicing factor PUF...
PUF60
505Annotation score:
A0A0J9YVP6A0A0J9YVP6_HUMAN
Poly(U)-binding-splicing factor PUF...
PUF60
534Annotation score:
There are more potential isoformsShow all

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei314Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC105219 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000632477; ENSP00000487637; ENSG00000274081

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC105219 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliA0A0J9YVR6
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiA0A0J9YVR6

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000632477; ENSP00000487637; ENSG00000274081

Organism-specific databases

HGNCiHGNC:17042 PUF60
GenAtlasiSearch...

Miscellaneous databases

ChiTaRSiPUF60 human

Family and domain databases

CDDicd12370 RRM1_PUF60, 1 hit
cd12371 RRM2_PUF60, 1 hit
Gene3Di3.30.70.330, 2 hits
InterProiView protein in InterPro
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR006532 PolyU-bd
IPR034209 PUF60_RRM1
IPR034211 PUF60_RRM2
IPR035979 RBD_domain_sf
IPR000504 RRM_dom
PfamiView protein in Pfam
PF00076 RRM_1, 2 hits
SMARTiView protein in SMART
SM00360 RRM, 2 hits
SUPFAMiSSF54928 SSF54928, 2 hits
TIGRFAMsiTIGR01645 half-pint, 1 hit
PROSITEiView protein in PROSITE
PS50102 RRM, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiA0A0J9YVR6_HUMAN
AccessioniPrimary (citable) accession number: A0A0J9YVR6
Entry historyiIntegrated into UniProtKB/TrEMBL: October 14, 2015
Last sequence update: October 5, 2016
Last modified: September 12, 2018
This is version 29 of the entry and version 3 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again