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Protein

Hypoxanthine phosphoribosyltransferase

Gene

PVIIG_02072

Organism
Plasmodium vivax India VII
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

IMP + diphosphate = hypoxanthine + 5-phospho-alpha-D-ribose 1-diphosphate.UniRule annotation

Cofactori

Mg2+UniRule annotation

Pathwayi: IMP biosynthesis via salvage pathway

This protein is involved in step 1 of the subpathway that synthesizes IMP from hypoxanthine.UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Hypoxanthine phosphoribosyltransferase (PVIIG_02072)
This subpathway is part of the pathway IMP biosynthesis via salvage pathway, which is itself part of Purine metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes IMP from hypoxanthine, the pathway IMP biosynthesis via salvage pathway and in Purine metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferaseUniRule annotationImported, Transferase
Biological processPurine salvageUniRule annotation
LigandMagnesiumUniRule annotation, Metal-bindingUniRule annotation, Nucleotide-bindingUniRule annotation

Enzyme and pathway databases

UniPathwayiUPA00591; UER00648

Names & Taxonomyi

Protein namesi
Recommended name:
Hypoxanthine phosphoribosyltransferaseUniRule annotation (EC:2.4.2.8UniRule annotation)
Gene namesi
ORF Names:PVIIG_02072Imported
OrganismiPlasmodium vivax India VIIImported
Taxonomic identifieri1077284 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiidaePlasmodiumPlasmodium (Plasmodium)
Proteomesi
  • UP000053562 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliA0A0J9SD35
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini50 – 205PribosyltranInterPro annotationAdd BLAST156

Sequence similaritiesi

Belongs to the purine/pyrimidine phosphoribosyltransferase family.UniRule annotation

Family and domain databases

CDDicd06223 PRTases_typeI, 1 hit
InterProiView protein in InterPro
IPR005904 Hxn_phspho_trans
IPR000836 PRibTrfase_dom
IPR029057 PRTase-like
PfamiView protein in Pfam
PF00156 Pribosyltran, 1 hit
SUPFAMiSSF53271 SSF53271, 1 hit
TIGRFAMsiTIGR01203 HGPRTase, 1 hit

Sequencei

Sequence statusi: Complete.

A0A0J9SD35-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKIPNNPGAG ENALEPIYIK DDDGYDIDTF LIPDHYKNYI TKVLIPNGVL
60 70 80 90 100
KNRIEKLAFD IKQVYRNEEF HVICLLKGSR GFFSALLKYL NRIHNYSSTE
110 120 130 140 150
SPKHLYVEHY VRVKSYCNDQ SLDRIEIVSE DLSCLKDKHV LIVEDIIDTG
160 170 180 190 200
KTLLKFCEYL KKFEVKTIAI TCLFIKRTPL WNGFKADFVG FSIPDAFVVG
210 220 230
YSLDYNEKFR DLDHLCLVND EGIKKFRTAP PTA
Length:233
Mass (Da):26,970
Last modified:October 14, 2015 - v1
Checksum:iD0C4A44BE9A5CD05
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KQ234266 Genomic DNA Translation: KMZ80854.1

Genome annotation databases

EnsemblProtistsiKMZ80854; KMZ80854; PVIIG_02072

Similar proteinsi

Entry informationi

Entry nameiA0A0J9SD35_PLAVI
AccessioniPrimary (citable) accession number: A0A0J9SD35
Entry historyiIntegrated into UniProtKB/TrEMBL: October 14, 2015
Last sequence update: October 14, 2015
Last modified: July 18, 2018
This is version 18 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

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