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Entry version 17 (11 Dec 2019)
Sequence version 1 (14 Oct 2015)
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Protein
Submitted name:

Reverse ribonuclease integrase

Gene

RF55_14090

Organism
Lasius niger (Black garden ant)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Reverse ribonuclease integraseImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:RF55_14090Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiLasius niger (Black garden ant)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri67767 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaHymenopteraApocritaAculeataFormicoideaFormicidaeFormicinaeLasiusLasius
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000036403 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1 – 35SAPInterPro annotationAdd BLAST35
Domaini449 – 629Reverse transcriptaseInterPro annotationAdd BLAST181
Domaini973 – 1131Integrase catalyticInterPro annotationAdd BLAST159

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni36 – 56DisorderedSequence analysisAdd BLAST21
Regioni1245 – 1279DisorderedSequence analysisAdd BLAST35

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1259 – 1273PolarSequence analysisAdd BLAST15

Phylogenomic databases

Database of Orthologous Groups

More...
OrthoDBi
583605at2759

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.40.70.10, 1 hit
3.30.420.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001584 Integrase_cat-core
IPR041588 Integrase_H2C2
IPR021109 Peptidase_aspartic_dom_sf
IPR005162 Retrotrans_gag_dom
IPR012337 RNaseH-like_sf
IPR036397 RNaseH_sf
IPR000477 RT_dom
IPR041373 RT_RNaseH
IPR003034 SAP_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF17921 Integrase_H2C2, 1 hit
PF03732 Retrotrans_gag, 1 hit
PF17917 RT_RNaseH, 1 hit
PF00665 rve, 1 hit
PF00078 RVT_1, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF53098 SSF53098, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50994 INTEGRASE, 1 hit
PS50878 RT_POL, 1 hit
PS50800 SAP, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A0J7K8R1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MYHASKSELA DLATARGLDA SGTVEDLRRR LRDYLERHPE EDTDLEPTAA
60 70 80 90 100
AGPSTETFTD ARDALRTPIT LTLPVPSFGP APGPPTDDAK VISQIRKWGC
110 120 130 140 150
HFDGKDPISF LERLAELRDA YGPSDQQLLK GLPELLRGDP LLWLRNNRDQ
160 170 180 190 200
WRTWTDFERD FRTQFLPRRY QAALRREITD RRQRSGEAFN KYATEMLTLM
210 220 230 240 250
RRAGGFNREE QVDRLYENMS PDYKMYVRYD DATSISELQA RAADFEHIEK
260 270 280 290 300
QRRDHLKATQ KTDDKPAVAA AYNKEECYSG SEVSFINDQT AERAQQLGYQ
310 320 330 340 350
RCDYEGQIQL ANGATAEIPG TVRLPVQIGS RTFTHEFSVL PTLESDVLIG
360 370 380 390 400
VDLWARTEII LPPPPPPTNL DTAPTCGKLG GLTPTSADER QRLEAFLATE
410 420 430 440 450
LEKFKAIRGL TDKASHQIRL KHATPIKQRY RPRNPAMQAI IDREVAEMEA
460 470 480 490 500
AGVIEPSRSA WSSPVVIVKK KDGKQRFCID FRKVNDVTER DAYPLPQITA
510 520 530 540 550
TLDKLRGARY LTTLDLKNGY WQVPLTPESR PITAFTIPGR GLYQFTVMPF
560 570 580 590 600
GLHSAPATFQ RLLDNVLGPE MEPNVFVYLD DIIVISATFD QHLRLLAEVF
610 620 630 640 650
HRLRDARLRL NPDKCRFCVD QLKYLGHVID REGIRTDPEK VSAVADWPEP
660 670 680 690 700
RTVKQVRQFL GMASWYRRFI EKFSTIAGPL TQLTKKNARW KWGEDEGRAF
710 720 730 740 750
RELKHTLVSA PVLACPDFTR RFVLQTDAST SGLGAVLTQN FEEGERVIAY
760 770 780 790 800
ASRTLNGAER NYSATELECL AVVWGIRRMK GYLEGYPFTV ITDHQSLRWL
810 820 830 840 850
QRLEAPTGRL ARWLFELQQY DVEVTYRRGV LNRVADALSR QPISCAATPL
860 870 880 890 900
RCKWYRRLLE EVNRDPARRP DYRITDGRLL RHLLHSLDFK EHPTERQWKE
910 920 930 940 950
CVPQEQRTAI IHRYHDAPTA GHLGIAKTIA RVAERFYWPG MFREIAGYVR
960 970 980 990 1000
ACQNCQAHKA DQVAPAGALH ATNIHRPWEH VTVDLVGPLP RSRKGHTWLF
1010 1020 1030 1040 1050
VLQDRFTKWV ELVPLRQATA GNTTKAITER VLLRHGRPDI VLSDNGTQFT
1060 1070 1080 1090 1100
SAAFKNRLAE FGIQHRTAPV YAPHCNPVER TNRTIKTMIS QFVENDHRAW
1110 1120 1130 1140 1150
DEHLPALQFA FNTAVHDATG YTPAYLNHGR ELDAPHELPA APAIEPSTIR
1160 1170 1180 1190 1200
RHLEEAYELV RINLARAFQR QEKYYNLRRR PWRPQIGDWV WRRDHQLSKK
1210 1220 1230 1240 1250
AEDFNAKLAP KFIGPLEVRR VISPVIVDLR SKRGKWYRHT HVQHLKPARG
1260 1270
KINKNNDNNN EDELPPLNNN ELNNGNHDD
Length:1,279
Mass (Da):146,861
Last modified:October 14, 2015 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i7D2CDB03ED38131F
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
LBMM01011454 Genomic DNA Translation: KMQ86828.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LBMM01011454 Genomic DNA Translation: KMQ86828.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Phylogenomic databases

OrthoDBi583605at2759

Family and domain databases

Gene3Di2.40.70.10, 1 hit
3.30.420.10, 1 hit
InterProiView protein in InterPro
IPR001584 Integrase_cat-core
IPR041588 Integrase_H2C2
IPR021109 Peptidase_aspartic_dom_sf
IPR005162 Retrotrans_gag_dom
IPR012337 RNaseH-like_sf
IPR036397 RNaseH_sf
IPR000477 RT_dom
IPR041373 RT_RNaseH
IPR003034 SAP_dom
PfamiView protein in Pfam
PF17921 Integrase_H2C2, 1 hit
PF03732 Retrotrans_gag, 1 hit
PF17917 RT_RNaseH, 1 hit
PF00665 rve, 1 hit
PF00078 RVT_1, 1 hit
SUPFAMiSSF53098 SSF53098, 1 hit
PROSITEiView protein in PROSITE
PS50994 INTEGRASE, 1 hit
PS50878 RT_POL, 1 hit
PS50800 SAP, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A0J7K8R1_LASNI
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A0J7K8R1
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 14, 2015
Last sequence update: October 14, 2015
Last modified: December 11, 2019
This is version 17 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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