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Protein
Submitted name:

Gag-pol polyprotein

Gene
N/A
Organism
HIV-1 M:CRF01_AE
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).SAAS annotation

GO - Molecular functioni

Keywordsi

Molecular functionAspartyl proteaseUniRule annotation, Hydrolase, Multifunctional enzymeSAAS annotation, Nucleotidyltransferase, Protease, RNA-directed DNA polymeraseSAAS annotation, Transferase

Names & Taxonomyi

Protein namesi
Submitted name:
Gag-pol polyproteinImported
OrganismiHIV-1 M:CRF01_AEImported
Taxonomic identifieri1345266 [NCBI]
Taxonomic lineageiVirusesOrterviralesRetroviridaeOrthoretrovirinaeLentivirus

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini70 – 139Peptidase A2InterPro annotationAdd BLAST70
Domaini193 – 383Reverse transcriptaseInterPro annotationAdd BLAST191

Sequence similaritiesi

Belongs to the retroviral Pol polyprotein family.UniRule annotation

Family and domain databases

CDDicd05482 HIV_retropepsin_like, 1 hit
Gene3Di2.40.70.10, 1 hit
InterProiView protein in InterPro
IPR001969 Aspartic_peptidase_AS
IPR001995 Peptidase_A2_cat
IPR021109 Peptidase_aspartic_dom_sf
IPR034170 Retropepsin-like_cat_dom
IPR018061 Retropepsins
IPR000477 RT_dom
IPR010659 RVT_connect
IPR010661 RVT_thumb
PfamiView protein in Pfam
PF00077 RVP, 1 hit
PF00078 RVT_1, 1 hit
PF06815 RVT_connect, 1 hit
PF06817 RVT_thumb, 1 hit
SUPFAMiSSF50630 SSF50630, 1 hit
PROSITEiView protein in PROSITE
PS50175 ASP_PROT_RETROV, 1 hit
PS00141 ASP_PROTEASE, 1 hit
PS50878 RT_POL, 1 hit

Sequencei

Sequence statusi: Fragment.

A0A0H5BLK0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
FFRENLAFPQ RKAREFSSEQ TRANSPTSRT DGGRDNPPTE AGGTSSSFNF
60 70 80 90 100
PQITLWQRPL VTVKVEGQLR EALLDTGADD TVLEDINLPG KWKPKMIGGI
110 120 130 140 150
GGFIKVRQYD QITIEICGKK AIGTVLVGPT PVNIIGRNML TQLGCTLNFP
160 170 180 190 200
ISPIDTVPVK LKPGMDGPKV KQWPLTEEKI KALTEICNEM EKEGKISKIG
210 220 230 240 250
PENPYNTPIF AIKKKDGTKW RKLVDFRELN KRTQDFWEVQ LGIPHPAGLK
260 270 280 290 300
KKKSVTVLDV GDAYFSVPLD ENFRKYTAFT IPSINNETPG IRYQYNVLPQ
310 320 330 340 350
GWKGSPAIFQ SSMTRILEPF RIKNPEIVIY QYMDDLYVGS DLEIGQHRTK
360 370 380 390 400
IEELRAHLLR WGFTTPDKKH QKEPPFLWMG YELHPDKWTV QPIELPEKDS
410 420 430 440 450
WTVNDIQKLV GKLNWASQIY AGIKIKQLCK LLRGAKALTD IVPLTAEAEL
460 470 480 490 500
ELAENREILK APVHGVYYDP SKDLVAEVQK QGEDQWTYQI YQEPFKNLKT
510 520 530 540 550
GKYAKKRSAH TNDVRQLTEV VQKIATESIV IWGKTPKFRL PIQRETWETW
560
WMEYWQATWI PEWEFVNTP
Length:569
Mass (Da):65,295
Last modified:October 14, 2015 - v1
Checksum:i7CABB1766A4576AC
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei569Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HG421510 Genomic RNA Translation: CDG41742.1

Similar proteinsi

Entry informationi

Entry nameiA0A0H5BLK0_9HIV1
AccessioniPrimary (citable) accession number: A0A0H5BLK0
Entry historyiIntegrated into UniProtKB/TrEMBL: October 14, 2015
Last sequence update: October 14, 2015
Last modified: July 18, 2018
This is version 15 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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