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UniProtKB - A0A0H3YFD7 (A0A0H3YFD7_SCHMD)

Entry version 14 (07 Oct 2020)
Sequence version 1 (14 Oct 2015)
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Protein
Submitted name:

Slc24a-7

Gene

slc24a-7

Organism
Schmidtea mediterranea (Freshwater planarian flatworm)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processAntiportARBA annotation, Calcium transportARBA annotation, Ion transport, Transport
LigandCalcium

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Slc24a-7Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:slc24a-7Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSchmidtea mediterranea (Freshwater planarian flatworm)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri79327 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Spiralia › Lophotrochozoa › Platyhelminthes › Rhabditophora › Seriata › Tricladida › Continenticola › Geoplanoidea › Dugesiidae › Schmidtea

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei54 – 81HelicalSequence analysisAdd BLAST28
Transmembranei120 – 143HelicalSequence analysisAdd BLAST24
Transmembranei155 – 174HelicalSequence analysisAdd BLAST20
Transmembranei180 – 204HelicalSequence analysisAdd BLAST25
Transmembranei624 – 646HelicalSequence analysisAdd BLAST23
Transmembranei658 – 680HelicalSequence analysisAdd BLAST23
Transmembranei686 – 705HelicalSequence analysisAdd BLAST20
Transmembranei712 – 737HelicalSequence analysisAdd BLAST26
Transmembranei757 – 779HelicalSequence analysisAdd BLAST23
Transmembranei791 – 811HelicalSequence analysisAdd BLAST21
Transmembranei823 – 847HelicalSequence analysisAdd BLAST25

Keywords - Cellular componenti

Membrane

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini55 – 197Na_Ca_exInterPro annotationAdd BLAST143
Domaini693 – 840Na_Ca_exInterPro annotationAdd BLAST148

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisARBA annotation

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR004837, NaCa_Exmemb

Pfam protein domain database

More...Pfami		View protein in Pfam
PF01699, Na_Ca_ex, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A0H3YFD7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAACTPLKFS SFNYSNACDY ITNFKGCSPN SGLINYYQWQ YCAFGNRWAP 
        60         70         80         90        100
GILMFLWFLF LLTGITTSAD SFLAPCLVVV AKTMRMSENL AGVTLLALGN 
       110        120        130        140        150
GAADVFSSLS AVTSNSNPNV GLAFGAILGA GVFVNAITAG IIMILSPFKI 
       160        170        180        190        200
MKRPILKDLL FYFVALIWCM IIFIKKQIEL WSSLVFLAIY VIYILVTVIS 
       210        220        230        240        250
RLLYVRNEKS NKTIIQTNNI SITITTPATN VENAEIQQQN IEDPLSILDF 
       260        270        280        290        300
ISINRDERSK GNRNLAANSI GITIAVPNDK VDQENDLNRP MKKSSTISDF 
       310        320        330        340        350
RSIHIGRSDT NQTSFPRFSH LKSHIAGSLR TNNVYSYDNP NYISDNSIDR 
       360        370        380        390        400
VYIASTNRSN FENNFHSIND NPNSLKELYA DKSDHLNVPG NIYQKKPNLI 
       410        420        430        440        450
KSQNSCPNDS ECHSHKRILS GYLNPLQLER FYNTLPSERP STEVNHLKYS 
       460        470        480        490        500
CSIKQKNLSP RSSIERSASH RSIRSMAKII IDNEHEKERM ENHPTAKKAN 
       510        520        530        540        550
LIKSLSLTVL NEYALKSNIR YWSMREIQKA KSDITNEWDI LEGNYKVHPE 
       560        570        580        590        600
NENENKFNIE TGENGDSVVT FPGPWKHFAL TILPVDLEEW REQSGFSKFL 
       610        620        630        640        650
SIIQSPFMFI LTLTIPIVDE TAYLKGWCKI LNCIHCLLSL VFWVLLPNVY 
       660        670        680        690        700
NTPFGTSNFL LVYLFIILGF IVGVVVAFTS KVDKPPIYQP FFAFIGLITS 
       710        720        730        740        750
ILWIYEIANE IVNILSVFGV VFNISSVILG LSVLAFANST GDLVSNVTLA 
       760        770        780        790        800
KNNYPRIGYS ACVGGPLFNL LVGIGIPFSI RTFSGPIPVQ LTGTSIVLIF 
       810        820        830        840        850
TIMLVTALNL LCLPLMKFQP KRFYGIILIT IYVIYFVLVI LFAVDIIKVT 

L
Length:851
Mass (Da):95,559
Last modified:October 14, 2015 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i8612758302D7E5CE
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
KT163617 mRNA Translation: AKN21567.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KT163617 mRNA Translation: AKN21567.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Family and domain databases

InterProiView protein in InterPro
IPR004837, NaCa_Exmemb
PfamiView protein in Pfam
PF01699, Na_Ca_ex, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A0H3YFD7_SCHMD
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A0H3YFD7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 14, 2015
Last sequence update: October 14, 2015
Last modified: October 7, 2020
This is version 14 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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