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Protein

Acetylornithine deacetylase

Gene

argE

Organism
Vibrio cholerae B33
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

N2-acetyl-L-ornithine + H2O = acetate + L-ornithine.UniRule annotationSAAS annotation

Cofactori

Protein has several cofactor binding sites:
  • Co2+SAAS annotation
  • glutathioneUniRule annotationSAAS annotation

Pathwayi: L-arginine biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes L-ornithine from N(2)-acetyl-L-ornithine (linear).SAAS annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Acetylornithine deacetylase (argE)
This subpathway is part of the pathway L-arginine biosynthesis, which is itself part of Amino-acid biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes L-ornithine from N(2)-acetyl-L-ornithine (linear), the pathway L-arginine biosynthesis and in Amino-acid biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi76Cobalt or zinc 1UniRule annotation1
Active sitei78UniRule annotation1
Metal bindingi108Cobalt or zinc 1UniRule annotation1
Metal bindingi108Cobalt or zinc 2UniRule annotation1
Active sitei140UniRule annotation1
Metal bindingi141Cobalt or zinc 2UniRule annotation1
Metal bindingi165Cobalt or zinc 1UniRule annotation1
Metal bindingi351Cobalt or zinc 2UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseUniRule annotationSAAS annotationImported
Biological processAmino-acid biosynthesis, Arginine biosynthesisUniRule annotationSAAS annotation
LigandCobaltUniRule annotationSAAS annotation, Metal-bindingUniRule annotationSAAS annotation, ZincUniRule annotationSAAS annotation

Enzyme and pathway databases

UniPathwayiUPA00068; UER00110

Names & Taxonomyi

Protein namesi
Recommended name:
Acetylornithine deacetylaseUniRule annotation (EC:3.5.1.16UniRule annotation)
Short name:
AOUniRule annotation
Short name:
AcetylornithinaseUniRule annotation
Alternative name(s):
N-acetylornithinaseUniRule annotation
Short name:
NAOUniRule annotation
Gene namesi
Name:argEUniRule annotation
ORF Names:VCE_001175Imported
OrganismiVibrio cholerae B33Imported
Taxonomic identifieri417400 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
Proteomesi
  • UP000004007 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Homodimer.UniRule annotationSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliA0A0H3Q451
SMRiA0A0H3Q451
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini174 – 285M20_dimerInterPro annotationAdd BLAST112

Sequence similaritiesi

Belongs to the peptidase M20A family. ArgE subfamily.UniRule annotationSAAS annotation

Family and domain databases

CDDicd03894 M20_ArgE, 1 hit
HAMAPiMF_01108 ArgE, 1 hit
InterProiView protein in InterPro
IPR010169 AcOrn-deacetyl
IPR001261 ArgE/DapE_CS
IPR036264 Bact_exopeptidase_dim_dom
IPR002933 Peptidase_M20
IPR011650 Peptidase_M20_dimer
PANTHERiPTHR43808:SF1 PTHR43808:SF1, 1 hit
PfamiView protein in Pfam
PF07687 M20_dimer, 1 hit
PF01546 Peptidase_M20, 1 hit
SUPFAMiSSF55031 SSF55031, 1 hit
TIGRFAMsiTIGR01892 AcOrn-deacetyl, 1 hit
PROSITEiView protein in PROSITE
PS00758 ARGE_DAPE_CPG2_1, 1 hit
PS00759 ARGE_DAPE_CPG2_2, 1 hit

Sequencei

Sequence statusi: Complete.

A0A0H3Q451-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPLPSFLEVY EGLISTSSIS STDARWDEGN EQVIAKLADW LSALGFSIQI
60 70 80 90 100
EQVAPNKQNL IAKLGSGEGG LLLAGHSDTV PFDEGRWNYN PHALTQVNNR
110 120 130 140 150
FYGLGTADMK GFFAFIYEAV KNVDWSKQTK PLYVLATCDE ETTMLGARHF
160 170 180 190 200
TENAPFKPDY CIIGEPTSLV PIRAHKGHVA NAIRVTGKSG HSSNPALGVN
210 220 230 240 250
AIEIMHEVLF ALMQLRDRLI KEYHHPGFEI PTPTLNLGHI HGGDSPNRIC
260 270 280 290 300
GCCELHYDVR PLPGISLDGL DNLMHDALRE VQQKWPGRIE LVPLHDPIPG
310 320 330 340 350
YECAHDHPFI HGISEICEQE AQTVNYCTEA PFLQQVCPTL VLGPGSIDQA
360 370
HQPDEFLAFE FIDPTVRVLS RAMQKYCF
Length:378
Mass (Da):41,964
Last modified:September 16, 2015 - v1
Checksum:iF0CC5EC1892ECE8D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ACHZ01000015 Genomic DNA Translation: EEO18186.1
RefSeqiWP_001130865.1, NZ_DS178142.1

Genome annotation databases

EnsemblBacteriaiEEO18186; EEO18186; VCE_001175

Similar proteinsi

Entry informationi

Entry nameiA0A0H3Q451_VIBCL
AccessioniPrimary (citable) accession number: A0A0H3Q451
Entry historyiIntegrated into UniProtKB/TrEMBL: September 16, 2015
Last sequence update: September 16, 2015
Last modified: May 23, 2018
This is version 24 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

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