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Entry version 17 (02 Dec 2020)
Sequence version 1 (16 Sep 2015)
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Protein
Submitted name:

Type VI secretion protein IcmF

Gene

YPK_1485

Organism
Yersinia pseudotuberculosis serotype O:3 (strain YPIII)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Type VI secretion protein IcmFImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Ordered Locus Names:YPK_1485Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiYersinia pseudotuberculosis serotype O:3 (strain YPIII)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri502800 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesYersiniaceaeYersinia
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000721 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei49 – 66HelicalSequence analysisAdd BLAST18
Transmembranei71 – 92HelicalSequence analysisAdd BLAST22
Transmembranei104 – 123HelicalSequence analysisAdd BLAST20
Transmembranei529 – 550HelicalSequence analysisAdd BLAST22

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
A0A0H3B3I5

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini253 – 535IcmF-related_NInterPro annotationAdd BLAST283
Domaini586 – 898IcmF-relatedInterPro annotationAdd BLAST313
Domaini1144 – 1247IcmF_CInterPro annotationAdd BLAST104

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

Identification of Orthologs from Complete Genome Data

More...
OMAi
RAEIFRF

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR009612, IcmF-related
IPR025743, IcmF-related_N_dom
IPR010623, IcmF_C
IPR027417, P-loop_NTPase
IPR017731, TssM1-like

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF06761, IcmF-related, 1 hit
PF14331, IcmF-related_N, 1 hit
PF06744, IcmF_C, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540, SSF52540, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR03348, VI_IcmF, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

A0A0H3B3I5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSYLNRLFSG WAMKRILLVG CFILLAAAIW FLGPFLGFGE ARPLESYEAR
60 70 80 90 100
IICILLALLL ILGFWYGAPR FVIAAVVACA AVWVIGPFIL VGDDHPLTDG
110 120 130 140 150
IRRGIIIAII AFITLIYGTW CLVKALAKNP ALLDNFIKHK KAAKPEAEAE
160 170 180 190 200
LSEVNAMIRN GMNYVRRIHS GIPAWRRFFI SSRWRTELPW FMVVGMKGAG
210 220 230 240 250
KTALILSSGQ DFPLPEQLNR IGKENPPTQH CECLFSNDAL FLDTSGKYID
260 270 280 290 300
DSKDNQTEWS GILKALKKYR PVKAINGVIV AISASDILGK SKADLLNVSA
310 320 330 340 350
TLRTRLDEVR AVLGVRFPVY VTITKLDQLS GFDEYFRNLT AEDREQIWGV
360 370 380 390 400
TFPYNEAKEQ SDMPLQQRIS HELALLEDRI SNNMHVRQQE EYAVADRKGM
410 420 430 440 450
YALPQDFRML SQRVTEVLQN VFFASRFDET KFHTTLRGIY FVSSCQPADV
460 470 480 490 500
ELLNNNTLIQ KWRNVINHKK PLSPADLSQK SDNEDRFISD VAYGKQYFLK
510 520 530 540 550
QLFSDVITKD ADLVSYNLKV QSKYRFQNLL GHAACIGLAV WLVWAFLVSF
560 570 580 590 600
QHNEGYLQAT GAKLSQLEST VMSYAKTSNE QILPALLNAT QQLPEYGTLD
610 620 630 640 650
VANPELDWRY GLYTGSAISQ GANTLYQFFL QKYLFPMVEH QSEVALRKTM
660 670 680 690 700
HSGQSEEVYA ALKLYLMLTG EGKFDRQYMI EHVTQDWQKS GKIEPYEEKS
710 720 730 740 750
IFVGHLNTLF TLKDWRQYGQ PADSELIKQA RAILAEKTVT ARLWGRIQSR
760 770 780 790 800
LLADAPANMT LRKMVGEHAT QVFTLSDDEL LHEGIPGLYT YAGYHEVVKK
810 820 830 840 850
KLTPLLMLLQ EEDRWVMAQS LSSSLDPLTL RQDVLVMYLQ GYAAYWKRFL
860 870 880 890 900
SSVRLISVDA DSAEYAQGLS LDIALLRTLV SENSPLLNLA RQAVKETTLA
910 920 930 940 950
EKEKAITDEI NIRTQGQLLS QAKKLQETIA FRENKLIKEW VDNRFESLRV
960 970 980 990 1000
FVNGEQSADA PGGNNLSVLQ GTQMSRIIGT LNDQYTRFVV YNSAFEYGDI
1010 1020 1030 1040 1050
PPLSQDGERI AVESQTWPDP FRNIIAPLLT GSSQKFENKV ITHTSKAIDM
1060 1070 1080 1090 1100
GVGEICRNTL QGRYPFAESE QIVSLNDFER FFGTDGTVDS YFKKNLESKV
1110 1120 1130 1140 1150
DTSSIPWRYK GSVSSEGLAF FEQAAMIRNV LFNTNDGKKM ALDFSVSVRY
1160 1170 1180 1190 1200
LAPTITQLIM NFDGNTVRYS HGPVTPAFFK WPGLRQGTIV SLTAQRQKAS
1210 1220 1230 1240 1250
AMPDILFRGP WALLQWADQA DEIRDEANGK QTLTYLMGKD RVELEVSGLT
1260 1270
HGGETISDLL RDFKCPSVND MNGIW
Length:1,275
Mass (Da):144,170
Last modified:September 16, 2015 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i01297DF2CF45A256
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CP000950 Genomic DNA Translation: ACA67778.1

NCBI Reference Sequences

More...
RefSeqi
WP_011192705.1, NZ_CP009792.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
ACA67778; ACA67778; YPK_1485

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
49785336

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ypy:YPK_1485

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|502800.11.peg.2123

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000950 Genomic DNA Translation: ACA67778.1
RefSeqiWP_011192705.1, NZ_CP009792.1

3D structure databases

SMRiA0A0H3B3I5
ModBaseiSearch...

Genome annotation databases

EnsemblBacteriaiACA67778; ACA67778; YPK_1485
GeneIDi49785336
KEGGiypy:YPK_1485
PATRICifig|502800.11.peg.2123

Phylogenomic databases

OMAiRAEIFRF

Family and domain databases

InterProiView protein in InterPro
IPR009612, IcmF-related
IPR025743, IcmF-related_N_dom
IPR010623, IcmF_C
IPR027417, P-loop_NTPase
IPR017731, TssM1-like
PfamiView protein in Pfam
PF06761, IcmF-related, 1 hit
PF14331, IcmF-related_N, 1 hit
PF06744, IcmF_C, 1 hit
SUPFAMiSSF52540, SSF52540, 1 hit
TIGRFAMsiTIGR03348, VI_IcmF, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A0H3B3I5_YERPY
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A0H3B3I5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: September 16, 2015
Last sequence update: September 16, 2015
Last modified: December 2, 2020
This is version 17 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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