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Protein

5'-deoxynucleotidase VC0395_A1564

Gene

VC0395_A1564

Organism
Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 / O395)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the strictly specific dephosphorylation of 2'-deoxyribonucleoside 5'-monophosphates.UniRule annotationSAAS annotation

Catalytic activityi

A 2'-deoxyribonucleoside 5'-monophosphate + H2O = a 2'-deoxyribonucleoside + phosphate.UniRule annotationSAAS annotation

Cofactori

a divalent metal cationUniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei57Appears to be important in orienting the phosphate for catalysisUniRule annotation1
Metal bindingi72Divalent metal cation; via tele nitrogenUniRule annotation1
Binding sitei72SubstrateUniRule annotation1
Metal bindingi107Divalent metal cation; via tele nitrogenUniRule annotation1
Metal bindingi108Divalent metal cationUniRule annotation1
Binding sitei108SubstrateUniRule annotation1
Metal bindingi176Divalent metal cationUniRule annotation1
Binding sitei176SubstrateUniRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolaseUniRule annotationSAAS annotation
LigandMetal-bindingUniRule annotationSAAS annotation, Nucleotide-bindingUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
5'-deoxynucleotidase VC0395_A1564UniRule annotation (EC:3.1.3.89UniRule annotation)
Alternative name(s):
5'-deoxyribonucleotidaseUniRule annotation
Nucleoside 5'-monophosphate phosphohydrolaseUniRule annotation
Gene namesi
Ordered Locus Names:VC0395_A1564Imported
OrganismiVibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 / O395)Imported
Taxonomic identifieri345073 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
Proteomesi
  • UP000000249 Componenti: Chromosome 2

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Homodimer.UniRule annotationSAAS annotation

Protein-protein interaction databases

STRINGi345073.VC0395_A1564

Structurei

3D structure databases

ProteinModelPortaliA0A0H3ANS2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini69 – 181HDInterPro annotationAdd BLAST113

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni57 – 58Substrate bindingUniRule annotation2
Regioni116 – 119Substrate bindingUniRule annotation4

Sequence similaritiesi

Belongs to the 5DNU family.UniRule annotationSAAS annotation

Phylogenomic databases

KOiK08722
OMAiNQSHFFA

Family and domain databases

CDDicd00077 HDc, 1 hit
HAMAPiMF_01100 5DNU, 1 hit
InterProiView protein in InterPro
IPR003607 HD/PDEase_dom
IPR006674 HD_domain
IPR039356 Nucleoside_monoPase
IPR022971 YfbR
PANTHERiPTHR11845 PTHR11845, 1 hit
PfamiView protein in Pfam
PF13023 HD_3, 1 hit
SMARTiView protein in SMART
SM00471 HDc, 1 hit
PROSITEiView protein in PROSITE
PS51831 HD, 1 hit

Sequencei

Sequence statusi: Complete.

A0A0H3ANS2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGRRSRLSFG TLKRACFFIF FSASSAVEKP IHQQGSESAM QESHFFAHLA
60 70 80 90 100
RMKLIQRWPL MRSISSENIS EHSLQVAFVA HALAVIKNKK FGGTLNPERI
110 120 130 140 150
ALLAMYHDTS EVLTGDLPTP IKYFNPEIAK EYKKIEAAAE RRLLDMLPEE
160 170 180 190 200
LRDDFRPFLI SNTADPDESA IVKQADAICA YLKCLEELSA GNHEYAQAKK
210 220 230
RLDVTLRERH SEEMAYFLQT FAPSFELTLD EIS
Length:233
Mass (Da):26,531
Last modified:September 16, 2015 - v1
Checksum:i0EBFAD4CEE6063EF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000627 Genomic DNA Translation: ABQ22068.1

Genome annotation databases

EnsemblBacteriaiABQ22068; ABQ22068; VC0395_A1564
KEGGivco:VC0395_A1564
PATRICifig|345073.21.peg.2021

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000627 Genomic DNA Translation: ABQ22068.1

3D structure databases

ProteinModelPortaliA0A0H3ANS2
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi345073.VC0395_A1564

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABQ22068; ABQ22068; VC0395_A1564
KEGGivco:VC0395_A1564
PATRICifig|345073.21.peg.2021

Phylogenomic databases

KOiK08722
OMAiNQSHFFA

Family and domain databases

CDDicd00077 HDc, 1 hit
HAMAPiMF_01100 5DNU, 1 hit
InterProiView protein in InterPro
IPR003607 HD/PDEase_dom
IPR006674 HD_domain
IPR039356 Nucleoside_monoPase
IPR022971 YfbR
PANTHERiPTHR11845 PTHR11845, 1 hit
PfamiView protein in Pfam
PF13023 HD_3, 1 hit
SMARTiView protein in SMART
SM00471 HDc, 1 hit
PROSITEiView protein in PROSITE
PS51831 HD, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A0H3ANS2_VIBC3
AccessioniPrimary (citable) accession number: A0A0H3ANS2
Entry historyiIntegrated into UniProtKB/TrEMBL: September 16, 2015
Last sequence update: September 16, 2015
Last modified: September 12, 2018
This is version 15 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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