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Entry version 38 (05 Jun 2019)
Sequence version 1 (22 Jul 2015)
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Protein

Integrin beta

Gene

Itgb4

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionIntegrinUniRule annotationImported
Biological processCell adhesionUniRule annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Integrin betaUniRule annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Itgb4Imported
ORF Names:rCG_33384Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiRattus norvegicus (Rat)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10116 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002494 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 10

Organism-specific databases

Rat genome database

More...
RGDi
2928 Itgb4

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei713 – 735HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 27Sequence analysisAdd BLAST27
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_501402455728 – 1807Integrin betaSequence analysisAdd BLAST1780

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSRNOG00000005580 Expressed in 10 organ(s), highest expression level in colon

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
A0A0G2K4V5

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1131 – 1220Fibronectin type-IIIInterPro annotationAdd BLAST90
Domaini1224 – 1323Fibronectin type-IIIInterPro annotationAdd BLAST100
Domaini1514 – 1609Fibronectin type-IIIInterPro annotationAdd BLAST96
Domaini1627 – 1723Fibronectin type-IIIInterPro annotationAdd BLAST97

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1118 – 1141DisorderedSequence analysisAdd BLAST24

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the integrin beta chain family.UniRule annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00960000186593

Identification of Orthologs from Complete Genome Data

More...
OMAi
KVKYWIQ

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00063 FN3, 4 hits

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.10, 4 hits
2.60.40.2030, 1 hit
3.40.50.410, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR038081 CalX-like_sf
IPR003644 Calx_beta
IPR013032 EGF-like_CS
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR040622 I-EGF_1
IPR013783 Ig-like_fold
IPR033760 Integrin_beta_N
IPR015812 Integrin_bsu
IPR012013 Integrin_bsu-4
IPR012896 Integrin_bsu_tail
IPR036349 Integrin_bsu_tail_dom_sf
IPR002369 Integrin_bsu_VWA
IPR036465 vWFA_dom_sf

The PANTHER Classification System

More...
PANTHERi
PTHR10082 PTHR10082, 4 hits
PTHR10082:SF42 PTHR10082:SF42, 4 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03160 Calx-beta, 1 hit
PF00041 fn3, 4 hits
PF18372 I-EGF_1, 1 hit
PF07965 Integrin_B_tail, 1 hit
PF00362 Integrin_beta, 1 hit
PF17205 PSI_integrin, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF002513 Integrin_B4, 2 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR01186 INTEGRINB

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00237 Calx_beta, 1 hit
SM00060 FN3, 4 hits
SM00187 INB, 1 hit
SM01242 Integrin_B_tail, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF141072 SSF141072, 1 hit
SSF49265 SSF49265, 2 hits
SSF53300 SSF53300, 1 hit
SSF69687 SSF69687, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00022 EGF_1, 1 hit
PS50853 FN3, 4 hits
PS00243 INTEGRIN_BETA, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

A0A0G2K4V5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAGLCSSPWV KLLLAVVLSA GLPGNMANRC KKAQVKSCTE CIRVDKSCAY
60 70 80 90 100
CTDELFKERR CNTQAELLAA GCRGESVLVM ESSLEITENI QIDTSLHRSQ
110 120 130 140 150
VSPQGLQVRL RPGEERNFVF KVFEPLESPV DLYILMDFSN SMSDDLDNLK
160 170 180 190 200
QMGQNLAKIL RQLTSDYTIG FGKFVDKVSV PQTDMRPEKL KEPWPNSDPP
210 220 230 240 250
FSFKNVISLT ENVEEFWDKL QGERISGNLD APEGGFDAIL QTAVCTRDIG
260 270 280 290 300
WRADSTHLLV FSTESAFHYE ADGANVLAGI MNRNDEKCHL DATGAYTQYK
310 320 330 340 350
TQDYPSVPTL VRLLAKHNII PIFAVTNYSY SYYEKLHKYF PVSSLGVLQE
360 370 380 390 400
DSSNIVELLE EAFYRIRSNL DIRALDSPRG LRTEVTSDTL QKTETGSFHI
410 420 430 440 450
KRGEVGTYNV HLRAVEDIDG THVCQMAKED QRGNIHLKPS FSDGLRMDAS
460 470 480 490 500
VICDVCACEL QKEVQSARCH YRGDFMCGHC VCNEGWSGKT CNCSTGSLSD
510 520 530 540 550
TQPCLREGED KPCSGHGECQ CGRCVCYGEG RYEGHFCEYD NFQCPRTSGF
560 570 580 590 600
LCNDRGRCSM GECVCEPGWT GRSCDCPLSN ATCIDSNGGI CNGLGFCECG
610 620 630 640 650
RCHCNQRSSL YTDTTCEINY SAIRLGLCED LRSCVQCQAW GTGEKKGRTC
660 670 680 690 700
EECNFKVKMV DELKKAEEVV EYCSFRDEDD DCTYSYTVEG DGSPGPNSTV
710 720 730 740 750
LVHKKKDCPP GSFWWLIPLL IFLLLLLVLL LLLCWKYCAC CKACLGLLPC
760 770 780 790 800
CNQGHMVGFK EDHYMLRENL MASDHLDTPM LRSGNLKGRD TVRWKITNNV
810 820 830 840 850
QRPGFATHAA SISPTELVPY GLSLRLGRLC TENLMKPGTR ECDQLRQEVE
860 870 880 890 900
ENLNEVYRQV NGVHKLQQTK FRQQPNAGKK QDHTIVDTVL LAPRSAKQSL
910 920 930 940 950
LKLTEKQVEQ GSFHELKVAP GYYTLTAEQD ARGMVEFQEG VELVDVRVPL
960 970 980 990 1000
FIRPEDDDEK QLLVEAIDVP VGTATLGRRL VNITIIKEQA SGIVSFEQPE
1010 1020 1030 1040 1050
YSVSRGDQVA RIPVIRHILD NGKSQVSYST QDNTAHGHRD YVPVEGELLF
1060 1070 1080 1090 1100
YPGETWKELQ VKLLELQEVD SLLRGRQVRR FQVQLSNPKF GARLGQPNTA
1110 1120 1130 1140 1150
TVIIGEQDET DRSLINEISA SPPLPRGDLG APQNPNAKAA GSRKIHFNWL
1160 1170 1180 1190 1200
PPPGKPMGYR VKYWVQGDSE SEAHLLDSKV PSVELTNLYP YCDYEMKVCA
1210 1220 1230 1240 1250
YGAHGEGPYS SLVSCRTHQE VPSEPGRLAF NVVSSTVTQL SWAEPAETNG
1260 1270 1280 1290 1300
EITAYEVCYG LVNEDNRPIG PMKKVLVDNP KNRMLLIENL RESQPYRYTV
1310 1320 1330 1340 1350
KARNGAGWGP EREAIINLAT QPKRPMSIPI IPDIPIVDAQ GGEDYENFLM
1360 1370 1380 1390 1400
YSDDVLRSPA SSQRPSVSDD TEHLVNGRMD FAYPGSANSL HRMTAANVAY
1410 1420 1430 1440 1450
GTHLSPHQTH RMLSTSSTLT RDYHSLTRTD HSQSGTLPRD YSTLTSLSSQ
1460 1470 1480 1490 1500
GLPPIWEDGR SRLPLSWTLG SWSRAQMKGV PASRGSPDSI ILAGQSAAPS
1510 1520 1530 1540 1550
WGTDSRGAMG VPDTPTRLVF SALGPTSLKV SWQEPQCDRA LLGYSVEYQL
1560 1570 1580 1590 1600
LNGGEMHRLN IPNPGQTSVV VEDLLPNHSY VFRVRAQSQE GWGREREGVI
1610 1620 1630 1640 1650
TIESQVHPQS PLCPLPGSAF TLSTPSAPGP LVFTALSPDS LQLSWERPRR
1660 1670 1680 1690 1700
PNGDILGYLV TCEMAQGGGP ARTFRVDGDN PESRLTVPGL SENVPYKFKV
1710 1720 1730 1740 1750
QARTTEGFGP EREGIITIES QDGGPFPQLG SHSGLFQNPL QSEYSTVTST
1760 1770 1780 1790 1800
HSTTTTEPFL IDGLTLGTQR LEAGGSLTRH VTQEFVSRTL TTSGSLSTHM

DQQFFQT
Length:1,807
Mass (Da):200,623
Last modified:July 22, 2015 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i7C181435C482D327
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q64632ITB4_RAT
Integrin beta-4
Itgb4
1,807Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F1LSD3F1LSD3_RAT
Integrin beta
Itgb4
1,806Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC130970 Genomic DNA No translation available.
CH473948 Genomic DNA Translation: EDM06631.1
CH473948 Genomic DNA Translation: EDM06632.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSRNOT00000086747; ENSRNOP00000073188; ENSRNOG00000005580

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC130970 Genomic DNA No translation available.
CH473948 Genomic DNA Translation: EDM06631.1
CH473948 Genomic DNA Translation: EDM06632.1

3D structure databases

SMRiA0A0G2K4V5
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000086747; ENSRNOP00000073188; ENSRNOG00000005580

Organism-specific databases

RGDi2928 Itgb4

Phylogenomic databases

GeneTreeiENSGT00960000186593
OMAiKVKYWIQ

Gene expression databases

BgeeiENSRNOG00000005580 Expressed in 10 organ(s), highest expression level in colon

Family and domain databases

CDDicd00063 FN3, 4 hits
Gene3Di2.60.40.10, 4 hits
2.60.40.2030, 1 hit
3.40.50.410, 1 hit
InterProiView protein in InterPro
IPR038081 CalX-like_sf
IPR003644 Calx_beta
IPR013032 EGF-like_CS
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR040622 I-EGF_1
IPR013783 Ig-like_fold
IPR033760 Integrin_beta_N
IPR015812 Integrin_bsu
IPR012013 Integrin_bsu-4
IPR012896 Integrin_bsu_tail
IPR036349 Integrin_bsu_tail_dom_sf
IPR002369 Integrin_bsu_VWA
IPR036465 vWFA_dom_sf
PANTHERiPTHR10082 PTHR10082, 4 hits
PTHR10082:SF42 PTHR10082:SF42, 4 hits
PfamiView protein in Pfam
PF03160 Calx-beta, 1 hit
PF00041 fn3, 4 hits
PF18372 I-EGF_1, 1 hit
PF07965 Integrin_B_tail, 1 hit
PF00362 Integrin_beta, 1 hit
PF17205 PSI_integrin, 1 hit
PIRSFiPIRSF002513 Integrin_B4, 2 hits
PRINTSiPR01186 INTEGRINB
SMARTiView protein in SMART
SM00237 Calx_beta, 1 hit
SM00060 FN3, 4 hits
SM00187 INB, 1 hit
SM01242 Integrin_B_tail, 1 hit
SUPFAMiSSF141072 SSF141072, 1 hit
SSF49265 SSF49265, 2 hits
SSF53300 SSF53300, 1 hit
SSF69687 SSF69687, 1 hit
PROSITEiView protein in PROSITE
PS00022 EGF_1, 1 hit
PS50853 FN3, 4 hits
PS00243 INTEGRIN_BETA, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A0G2K4V5_RAT
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A0G2K4V5
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 22, 2015
Last sequence update: July 22, 2015
Last modified: June 5, 2019
This is version 38 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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