Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Propionyl-CoA carboxylase alpha chain, mitochondrial

Gene

Pcca

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Cofactori

biotinSAAS annotation

GO - Molecular functioni

Keywordsi

Molecular functionLigaseSAAS annotation
LigandATP-bindingPROSITE-ProRule annotationSAAS annotation, BiotinSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-RNO-196780 Biotin transport and metabolism
R-RNO-71032 Propionyl-CoA catabolism

Names & Taxonomyi

Protein namesi
Submitted name:
Propionyl-CoA carboxylase alpha chain, mitochondrialImported
Gene namesi
Name:PccaImported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 15

Organism-specific databases

RGDi3264 Pcca

Expressioni

Gene expression databases

BgeeiENSRNOG00000057042
ExpressionAtlasiA0A0G2K401 baseline and differential

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini57 – 504Biotin carboxylationInterPro annotationAdd BLAST448
Domaini175 – 373ATP-graspInterPro annotationAdd BLAST199
Domaini644 – 723Lipoyl-bindingInterPro annotationAdd BLAST80

Phylogenomic databases

GeneTreeiENSGT00550000074675

Family and domain databases

Gene3Di3.30.1490.20, 1 hit
InterProiView protein in InterPro
IPR011761 ATP-grasp
IPR013815 ATP_grasp_subdomain_1
IPR005481 BC-like_N
IPR001882 Biotin_BS
IPR011764 Biotin_carboxylation_dom
IPR005482 Biotin_COase_C
IPR000089 Biotin_lipoyl
IPR005479 CbamoylP_synth_lsu-like_ATP-bd
IPR016185 PreATP-grasp_dom_sf
IPR011054 Rudment_hybrid_motif
IPR011053 Single_hybrid_motif
PfamiView protein in Pfam
PF02785 Biotin_carb_C, 1 hit
PF00289 Biotin_carb_N, 1 hit
PF00364 Biotin_lipoyl, 1 hit
PF02786 CPSase_L_D2, 1 hit
SMARTiView protein in SMART
SM00878 Biotin_carb_C, 1 hit
SUPFAMiSSF51230 SSF51230, 1 hit
SSF51246 SSF51246, 1 hit
SSF52440 SSF52440, 1 hit
PROSITEiView protein in PROSITE
PS50975 ATP_GRASP, 1 hit
PS50979 BC, 1 hit
PS00188 BIOTIN, 1 hit
PS50968 BIOTINYL_LIPOYL, 1 hit
PS00866 CPSASE_1, 1 hit
PS00867 CPSASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

A0A0G2K401-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGLWVRTVA LLAARRHWRR SSQQLLWTLK RAPVYSQQCL VVSRSLSSVE
60 70 80 90 100
YEPKEKTFDK ILIANRGEIA CRVIKTCRKM GIRTVAIHSD VDASSVHVKM
110 120 130 140 150
ADEAVCVGPA PTSKSYLNMD AIMEAIKKTG AQAVHPGYGF LSENKEFAKC
160 170 180 190 200
LTADDKQFIS PDTHAIPSLG DIISSPLLRK KNKALSVAGF GGVYYDADEA
210 220 230 240 250
VRIAREIGYP VMIKASAGGG GKGMRIAWDD EETRDGFRFS SQEAASSFGD
260 270 280 290 300
DRLLIEKFID NPRHIEIQVL GDKHGNALWL NERECSIQRR NQKVVEEAPS
310 320 330 340 350
IFLDPETRRA MGEQAVALAK AVKYSSAGTV EFLVDSQKNF YFLEMNTRLQ
360 370 380 390 400
VEHPVTECIT GLDLVQEMIL VAKGYPLRHK QEDIPISGWA VECRVYAEDP
410 420 430 440 450
YKSFGLPSIG RLSQYQEPIH LPGVRVDSGI QPGCDFSVLI DPVITKLVTY
460 470 480 490 500
GSDRAEALKR MEDALDSYVI RGVTHNIPLL REVIINTRFV KGDISTKFLS
510 520 530 540 550
DVYPDGFKGH MLTPSERDQL LAIASSLFVA SQLRAQRFQE HSRVPVIRPD
560 570 580 590 600
VAKWELSVKL HDEDHTVVAS NNGPTFNVEV DGSKLNVTST WNLASPLLSV
610 620 630 640 650
NVDGTQRTVQ CLSRDAGGNM SIQFLGTVYK VHILTKLAAE LNKFMLEKVP
660 670 680 690 700
KDTSSTLCSP MPGVVVAVSV KPGDMVAEGQ EICVIEAMKM QNSMTAGKMG
710 720
KVKLVHCKAG DTVGEGDLLV ELE
Length:723
Mass (Da):79,812
Last modified:July 22, 2015 - v1
Checksum:i8BB61DCAAF156A05
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07019563 Genomic DNA No translation available.
AABR07019564 Genomic DNA No translation available.
AABR07019565 Genomic DNA No translation available.
AABR07019566 Genomic DNA No translation available.
AABR07019567 Genomic DNA No translation available.
AABR07019568 Genomic DNA No translation available.
AABR07019569 Genomic DNA No translation available.
AABR07019570 Genomic DNA No translation available.
AABR07072481 Genomic DNA No translation available.
AC123185 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSRNOT00000077482; ENSRNOP00000072844; ENSRNOG00000057042

Similar proteinsi

Entry informationi

Entry nameiA0A0G2K401_RAT
AccessioniPrimary (citable) accession number: A0A0G2K401
Entry historyiIntegrated into UniProtKB/TrEMBL: July 22, 2015
Last sequence update: July 22, 2015
Last modified: May 23, 2018
This is version 21 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health