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Protein
Submitted name:

Keratin, type I cytoskeletal 10

Gene

Krt10

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Keratin, type I cytoskeletal 10Imported
Gene namesi
Name:Krt10Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 10

Organism-specific databases

RGDi1359092 Krt10

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Intermediate filamentPROSITE-ProRule annotationSAAS annotation

Expressioni

Gene expression databases

BgeeiENSRNOG00000030170 Expressed in 10 organ(s), highest expression level in liver
ExpressionAtlasiA0A0G2K2V6 baseline and differential

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini145 – 459IF rodInterPro annotationAdd BLAST315

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili149 – 183Sequence analysisAdd BLAST35
Coiled coili251 – 296Sequence analysisAdd BLAST46
Coiled coili310 – 337Sequence analysisAdd BLAST28
Coiled coili357 – 391Sequence analysisAdd BLAST35
Coiled coili403 – 451Sequence analysisAdd BLAST49

Sequence similaritiesi

Belongs to the intermediate filament family.PROSITE-ProRule annotationSAAS annotation

Keywords - Domaini

Coiled coilPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00900000140820

Family and domain databases

InterProiView protein in InterPro
IPR001664 IF
IPR018039 IF_conserved
IPR039008 IF_rod_dom
IPR002957 Keratin_I
PANTHERiPTHR23239 PTHR23239, 2 hits
PfamiView protein in Pfam
PF00038 Filament, 1 hit
PRINTSiPR01248 TYPE1KERATIN
SMARTiView protein in SMART
SM01391 Filament, 1 hit
PROSITEiView protein in PROSITE
PS00226 IF_ROD_1, 1 hit
PS51842 IF_ROD_2, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

A0A0G2K2V6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSVRFSSNSR QYSSARSGGG GGGGGGGSSI RVSSTKSSLG GGYSSGGFSG
60 70 80 90 100
GSFSRGSSSG GCFGGSSGGY GGFGGGSFGG GYGGGSFGGG YGGGSFGGGY
110 120 130 140 150
GGGSFGGGYG GGSFGGGSFG GGSFGGGSFG GGLGGDGGGL LSGNEKVTMQ
160 170 180 190 200
NLNDRLASYM NKVRDLEESN YELEGKIKEW YEKHGNSSQR EPRDYSKYYK
210 220 230 240 250
TIEDLKGQIV NLTTDNANVL LQIDNARLAA DDFRLKYENE VALRQSVEAD
260 270 280 290 300
INGLRRVLDE LTLSKADLEM QIESLTEELA YLKKNHEEEM KDLQNVSTGD
310 320 330 340 350
VNVEMNAAPG VDLTQLLNNM RNQYEQLAEK NRKDAEAWFN EKSKELTTEI
360 370 380 390 400
DSNIEQMSSH KSEITELRRT VQGLEIELQS QLALKQSLEA SLAETEGRYC
410 420 430 440 450
VQLSQIQSQI SALEEQLQQI RAETECQNAE YQQLLDIKTR LENEIQTYRS
460 470 480 490 500
LLEGEGGSGG GSYGGGGRGG GGHGGSYGGG STGGGGGSGS YGGGSSGGGG
510 520 530 540 550
HGGSSGGGYG GGSSSGGGHG GSSGGGYGGG SSSGGQSGSG GFKTSGSGGG

DQSSKGPRY
Length:559
Mass (Da):56,813
Last modified:July 22, 2015 - v1
Checksum:iBFFCABBBD2286AEF
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q6IFW6K1C10_RAT
Keratin, type I cytoskeletal 10
Krt10 Ka10
526Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC096439 Genomic DNA No translation available.
RefSeqiXP_006247453.1, XM_006247391.3
UniGeneiRn.125065

Genome annotation databases

EnsembliENSRNOT00000081709; ENSRNOP00000072394; ENSRNOG00000030170
GeneIDi450225

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC096439 Genomic DNA No translation available.
RefSeqiXP_006247453.1, XM_006247391.3
UniGeneiRn.125065

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000081709; ENSRNOP00000072394; ENSRNOG00000030170
GeneIDi450225

Organism-specific databases

CTDi3858
RGDi1359092 Krt10

Phylogenomic databases

GeneTreeiENSGT00900000140820

Gene expression databases

BgeeiENSRNOG00000030170 Expressed in 10 organ(s), highest expression level in liver
ExpressionAtlasiA0A0G2K2V6 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR001664 IF
IPR018039 IF_conserved
IPR039008 IF_rod_dom
IPR002957 Keratin_I
PANTHERiPTHR23239 PTHR23239, 2 hits
PfamiView protein in Pfam
PF00038 Filament, 1 hit
PRINTSiPR01248 TYPE1KERATIN
SMARTiView protein in SMART
SM01391 Filament, 1 hit
PROSITEiView protein in PROSITE
PS00226 IF_ROD_1, 1 hit
PS51842 IF_ROD_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A0G2K2V6_RAT
AccessioniPrimary (citable) accession number: A0A0G2K2V6
Entry historyiIntegrated into UniProtKB/TrEMBL: July 22, 2015
Last sequence update: July 22, 2015
Last modified: September 12, 2018
This is version 22 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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